28 results · Page 1 of 2

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
A Study to Evaluate Efficacy, Safety & Pharmacokinetics of the Port Delivery System (PDS) With Ranibizumab in Participants With Diabetic Macular Edema (DME) Compared With Intravitreal Ranibizumab; A Substudy to Evaluate the Safety of Re-implanting the PDS With Ranibizumab in Participants With DMEdiabetic macular edemaActive, not recruitingPhase 32026-10-08NCT04108156
CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DMEdiabetic macular edemaActive, not recruitingPhase 32026-10-02NCT07449923
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology ProductsBranch Vein Occlusion, Embolism and Thrombosis, Venous Thrombosis, cardiovascular disorder, central retinal vein occlusion, diabetic macular edema, eye disorder, retinal disorder, retinal vein occlusion, thrombotic disease, vascular disorderActive, not recruitingNot stated2026-10-02NCT05476926
A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)Neovascular Age-related Macular DegenerationRecruitingPhase 42026-10-02NCT04853251
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)Geographic Atrophy, eye disorder, macular degeneration, retinal degeneration, retinal disorderRecruitingPhase 2 / Phase 32026-09-30NCT06635148
A Study to Evaluate the Efficacy and Safety of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DMEDiabetic Macular Edema (DME)Active, not recruitingPhase 2 / Phase 32026-09-30NCT06571045
ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent StudyEye Diseases, Hereditary, Geographic Atrophy, Skin Abnormalities, Skin and Connective Tissue Diseases, connective tissue disorder, eye disorder, macular degeneration, primary anetoderma, retinal degeneration, retinal disorder, skin disorderEnrolling by invitationPhase 22026-09-28NCT05481827
A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)Geographic Atrophy, eye disorder, macular degeneration, retinal degeneration, retinal disorderRecruitingPhase 22026-09-23NCT06557460
A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular DegenerationGeographic Atrophy, eye disorder, macular degeneration, retinal degeneration, retinal disorderRecruitingPhase 1 / Phase 22026-09-22NCT07215234
A Study in Adults With Geographic AtrophyGeographic Atrophy, eye disorder, macular degeneration, retinal degeneration, retinal disorderRecruitingPhase 22026-09-21NCT07606365
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic AtrophyGeographic Atrophy, eye disorder, macular degeneration, retinal degeneration, retinal disorderRecruitingPhase 32026-09-18NCT06541704
A Phase 3b, Single-Arm Study of Aflibercept 8 mg Dosed Every 4 Weeks in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) or Diabetic Macular Edema (DME)diabetic macular edemaActive, not recruitingPhase 32026-09-18NCT06491914
A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVOEmbolism and Thrombosis, Venous Thrombosis, cardiovascular disorder, eye disorder, retinal disorder, retinal vein occlusion, thrombotic disease, vascular disorderRecruitingPhase 22026-09-04NCT07205887
A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUGANO) Primary Efficacy Will be Determined at Week 56wet macular degenerationActive, not recruitingPhase 32026-09-03NCT06668064
Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular DegenerationGeographic Atrophy, age-related macular degeneration, eye disorder, macular degeneration, retinal degeneration, retinal disorderRecruitingNot applicable2026-08-26NCT06662162
A Study of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DMEDiabetic Macular Edema (DME)Active, not recruitingPhase 2 / Phase 32026-08-20NCT06957080
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)Metaplasia, Neovascularization, Pathologic, Pathologic Processes, Pathological Conditions, Signs and Symptoms, age-related macular degeneration, choroidal neovascularization, eye disorder, macular degeneration, optic choroid disorder, retinal degeneration, retinal disorder, uveal disorder, wet macular degenerationRecruitingPhase 2 / Phase 32026-08-06NCT07496567
Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular DegenerationNeurologic Manifestations, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, blindness (disorder), eye disorder, macular degeneration, nervous system disorder, retinal degeneration, retinal disorder, vision disorderRecruitingPhase 22026-08-05NCT07630649
Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMDEye Diseases, Hereditary, Metaplasia, Neovascularization, Pathologic, Pathologic Processes, Pathological Conditions, Signs and Symptoms, age-related macular degeneration, choroidal neovascularization, eye disorder, macular degeneration, optic choroid disorder, retinal degeneration, retinal disorder, uveal disorder, wet macular degenerationActive, not recruitingPhase 32026-08-03NCT05407636
A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants With Neovascular Age-Related Macular DegenerationNeovascular Age-related Macular Degeneration (nAMD)Active, not recruitingPhase 42026-07-31NCT06795048
A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular DegenerationNeovascular Age-related Macular DegenerationActive, not recruitingPhase 1 / Phase 22026-07-16NCT06660667
4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degenerationeye disorder, macular degeneration, retinal degeneration, retinal disorder, wet macular degenerationActive, not recruitingPhase 32026-06-01NCT06864988
A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic AtrophyGeographic Atrophy, age-related macular degeneration, eye disorder, macular degeneration, retinal degeneration, retinal disorderActive, not recruitingPhase 22026-05-14NCT06722157
Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMDEye Diseases, Hereditary, Metaplasia, Neovascularization, Pathologic, Pathologic Processes, Pathological Conditions, Signs and Symptoms, age-related macular degeneration, choroidal neovascularization, eye disorder, macular degeneration, optic choroid disorder, retinal degeneration, retinal disorder, uveal disorder, wet macular degenerationActive, not recruitingPhase 2 / Phase 32026-04-28NCT04704921
A Phase I, Open-label, Multicenter, Dose-Escalating Study to Evaluate the Safety and Tolerability of KH658 Gene Therapy in Participants With Neovascular Age-related Macular Degenerationage-related macular degeneration, eye disorder, macular degeneration, retinal degeneration, retinal disorderActive, not recruitingPhase 12026-01-08NCT06825858