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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Pre-Exposure Prophylaxis Study of Lenacapavir in Cisgender Men, Transgender Women, Transgender Men, and Gender Nonbinary People at Risk for HIV InfectionPre-Exposure Prophylaxis of HIV InfectionActive, not recruitingPhase 32026-10-06NCT04925752
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a New Formulation of Cabotegravir Long-Acting Administered Intramuscularly in a 4-month Dosing Interval (Q4M)Blood-Borne Infections, Genital Diseases, HIV infectious disease, Infections, RNA Virus Infections, Urogenital Diseases, immune system disorder, inborn error of immunity, infectious disease, lentivirus infection, sexually transmitted disease, uterine carcinosarcoma, viral infectious disease, viral sexually transmitted diseaseActive, not recruitingPhase 22026-10-05NCT06741397
DOR/ISL in HIV-1 Antiretroviral Treatment-naïve Participants (MK-8591A-053)HIV-1 InfectionActive, not recruitingPhase 32026-10-05NCT05705349
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV PreventionBlood-Borne Infections, Genital Diseases, HIV infectious disease, Infections, RNA Virus Infections, Urogenital Diseases, immune system disorder, inborn error of immunity, infectious disease, lentivirus infection, sexually transmitted disease, uterine carcinosarcoma, viral infectious disease, viral sexually transmitted diseaseRecruitingNot stated2026-10-01NCT07473778
A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1Blood-Borne Infections, Genital Diseases, HIV infectious disease, Infections, RNA Virus Infections, Urogenital Diseases, immune system disorder, inborn error of immunity, infectious disease, lentivirus infection, sexually transmitted disease, uterine carcinosarcoma, viral infectious disease, viral sexually transmitted diseaseActive, not recruitingPhase 32026-10-01NCT06694805
Study to Evaluate the Safety and Efficacy of Lenacapavir (GS-6207) in Combination With an Optimized Background Regimen (OBR) in Heavily Treatment Experienced Participants Living With HIV-1 Infection With Multidrug ResistanceHIV-1-infectionActive, not recruitingPhase 2 / Phase 32026-10-01NCT04150068
Study of Lenacapavir as a Once-Yearly Injection for HIV Pre-exposure Prophylaxis (PrEP)HIV Pre-exposure ProphylaxisActive, not recruitingPhase 32026-08-28NCT07047716
Study of Lenacapavir, Teropavimab, and Zinlirvimab Versus Cabotegravir and Rilpivirine in Virologically Suppressed Adults With HIV-1 on Oral Daily Antiretroviral TherapyBlood-Borne Infections, Genital Diseases, HIV infectious disease, Infections, RNA Virus Infections, Urogenital Diseases, immune system disorder, inborn error of immunity, infectious disease, lentivirus infection, sexually transmitted disease, uterine carcinosarcoma, viral infectious disease, viral sexually transmitted diseaseRecruitingPhase 32026-08-14NCT07682961
Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Standard of Care in Virologically Suppressed People With HIV-1HIV-1-InfectionActive, not recruitingPhase 32026-05-29NCT06630299
Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed People With HIV-1HIV-1-infectionActive, not recruitingPhase 32026-04-30NCT06630286
Study of Oral Weekly Lepetegravir (Formerly GS-1720) and Lenacapavir Pacfosacil (Formerly GS-4182) Versus Biktarvy in People With HIV-1 Who Are Virologically SuppressedHIV-1-InfectionActive, not recruitingPhase 2 / Phase 32026-04-17NCT06544733
Study Evaluating the Safety and Efficacy of Islatravir in Combination With Lenacapavir in Virologically Suppressed People With HIVHIV-1 InfectionActive, not recruitingPhase 22026-02-04NCT05052996
A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) (MK-8591A-052)HIV-1 InfectionActive, not recruitingPhase 32025-11-18NCT05630755
CaRi-Heart Assessment of Risk and Evaluation of Inflammation in Coronary CT Angiography (CARE-CCTA)Arterial Occlusive Diseases, arteriosclerosis disorder, atherosclerosis, cardiovascular disorder, coronary artery disorder, heart disorder, myocardial ischemia, vascular disorderNot yet recruitingNot applicable2025-10-23NCT07220304