27 results · Page 1 of 2

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)Neovascular Age-related Macular DegenerationRecruitingPhase 32026-10-08NCT07007065
A Study to Evaluate Efficacy, Safety & Pharmacokinetics of the Port Delivery System (PDS) With Ranibizumab in Participants With Diabetic Macular Edema (DME) Compared With Intravitreal Ranibizumab; A Substudy to Evaluate the Safety of Re-implanting the PDS With Ranibizumab in Participants With DMEdiabetic macular edemaActive, not recruitingPhase 32026-10-08NCT04108156
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Functioncardiovascular disorder, heart disorder, heart failureRecruitingPhase 32026-10-02NCT06307652
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic RetinopathyDiabetes Complications, cardiovascular disorder, diabetes mellitus, diabetic peripheral angiopathy, diabetic retinopathy, endocrine system disorder, eye disorder, retinal disorder, vascular disorderActive, not recruitingPhase 22026-10-01NCT06321302
A Study to Evaluate the Efficacy and Safety of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DMEDiabetic Macular Edema (DME)Active, not recruitingPhase 2 / Phase 32026-09-30NCT06571045
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Studybone disorder, lumbar spinal stenosis, musculoskeletal system disorder, spinal stenosis, vertebral column disorderRecruitingNot stated2026-09-30NCT03072927
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular DegenerationNeovascular Age-related Macular Degeneration; nAMDRecruitingPhase 32026-09-29NCT07614776
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, blindness (disorder), eye disorder, nervous system disorder, vision disorder, wet macular degenerationRecruitingPhase 32026-09-24NCT07482176
AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunctioncorneal disorder, corneal edema, eye disorderActive, not recruitingPhase 32026-09-24NCT07368959
A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular DegenerationGeographic Atrophy, eye disorder, macular degeneration, retinal degeneration, retinal disorderRecruitingPhase 1 / Phase 22026-09-22NCT07215234
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic AtrophyGeographic Atrophy, eye disorder, macular degeneration, retinal degeneration, retinal disorderRecruitingPhase 32026-09-18NCT06541704
A Phase 3b, Single-Arm Study of Aflibercept 8 mg Dosed Every 4 Weeks in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) or Diabetic Macular Edema (DME)diabetic macular edemaActive, not recruitingPhase 32026-09-18NCT06491914
A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.Arterial Occlusive Diseases, Dyslipidemias, Hypercholesterolemia, Infarction, Lipid Metabolism Disorders, Necrosis, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, arteriosclerosis disorder, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, coronary artery disorder, coronary stenosis, heart disorder, hyperlipidemia, ischemic disease, metabolic disease, myocardial infarction, myocardial ischemia, nervous system disorder, stroke disorder, vascular disorderActive, not recruitingPhase 32026-09-04NCT05739383
Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular DiseaseArterial Occlusive Diseases, Dyslipidemias, Hypercholesterolemia, Lipid Metabolism Disorders, Nutritional and Metabolic Diseases, arteriosclerosis disorder, atherosclerosis, atherosclerotic cardiovascular disease, cardiovascular disorder, hyperlipidemia, metabolic disease, vascular disorderActive, not recruitingPhase 32026-08-25NCT05030428
A Study to Evaluate the Efficacy and Safety of Tabirafusp Tedromer Compared to Aflibercept in Participants With DME - ALTODiabetic Macular Edema (DME)RecruitingPhase 32026-08-21NCT07734844
A Study of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DMEDiabetic Macular Edema (DME)Active, not recruitingPhase 2 / Phase 32026-08-20NCT06957080
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)Metaplasia, Neovascularization, Pathologic, Pathologic Processes, Pathological Conditions, Signs and Symptoms, age-related macular degeneration, choroidal neovascularization, eye disorder, macular degeneration, optic choroid disorder, retinal degeneration, retinal disorder, uveal disorder, wet macular degenerationRecruitingPhase 2 / Phase 32026-08-06NCT07496567
Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMDEye Diseases, Hereditary, Metaplasia, Neovascularization, Pathologic, Pathologic Processes, Pathological Conditions, Signs and Symptoms, age-related macular degeneration, choroidal neovascularization, eye disorder, macular degeneration, optic choroid disorder, retinal degeneration, retinal disorder, uveal disorder, wet macular degenerationActive, not recruitingPhase 32026-08-03NCT05407636
A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular DegenerationNeovascular Age-related Macular DegenerationActive, not recruitingPhase 1 / Phase 22026-07-16NCT06660667
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular DegeneratioGeographic Atrophy Secondary to Age-related Macular DegenerationRecruitingPhase 22026-06-24NCT07215390
4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degenerationeye disorder, macular degeneration, retinal degeneration, retinal disorder, wet macular degenerationActive, not recruitingPhase 32026-06-01NCT06864988
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular DegenerationNeurologic Manifestations, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, blindness (disorder), eye disorder, nervous system disorder, vision disorder, wet macular degenerationActive, not recruitingPhase 32026-05-22NCT06856577
A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAKWet Age-related Macular DegenerationActive, not recruitingPhase 32026-04-29NCT06556368
Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMDEye Diseases, Hereditary, Metaplasia, Neovascularization, Pathologic, Pathologic Processes, Pathological Conditions, Signs and Symptoms, age-related macular degeneration, choroidal neovascularization, eye disorder, macular degeneration, optic choroid disorder, retinal degeneration, retinal disorder, uveal disorder, wet macular degenerationActive, not recruitingPhase 2 / Phase 32026-04-28NCT04704921
Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular EdemaDiabetic Macular Edema (DME)Active, not recruitingPhase 22025-10-30NCT06116916