Congenital Abnormalities
Congenital Abnormalities
Explore linked clinical trials. Standard reference: MESH:M00000132,006 results · Page 1 of 81
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Absorption, Distribution, Metabolism, and Excretion of 14C-VX-407 After a Single Oral Dose | Abnormalities, Multiple, Ciliopathies, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Urogenital Diseases, autosomal dominant polycystic kidney disease, cystic kidney disease, hereditary disease, kidney disorder, polycystic kidney disease, urinary system disorder | Not yet recruiting | Phase 1 | 2026-10-09 | NCT07868926 | |
| Treatment of Low-flow Vascular Malformations With Bleomycin Electrosclerotherapy (BEST) | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiovascular disorder, vascular malformation | Recruiting | Phase 2 | 2026-10-09 | NCT07579962 | |
| The Corrective Power of Subtalar Arthrodesis With Mini/Medial Bone Block (SAMBB) in Patients Affected by Progressive Collapsing Foot Deformity (PCFD): Analysis Using Weight-bearing Cone Beam CT. | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Foot Deformities, Foot Deformities, Acquired, Foot Deformities, Congenital, Limb Deformities, Congenital, Lower Extremity Deformities, Congenital, Musculoskeletal Abnormalities, clubfoot, flatfoot, musculoskeletal system disorder | Not yet recruiting | Not applicable | 2026-10-09 | NCT07515170 | |
| A Study to Investigate the Effects and Safety of Codabakalner for the Treatment of FXS in Male Participants and Adult Participants With ADS | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Neurobehavioral Manifestations, Neurologic Manifestations, Sex Chromosome Disorders, X-linked disease, autism, autism spectrum disorder, chromosomal disorder, fragile X syndrome, hereditary disease, inherited neurodegenerative disorder, intellectual disability, nervous system disorder, neurodevelopmental disorder, pervasive developmental disorder, psychiatric disorder | Not yet recruiting | Phase 2 / Phase 3 | 2026-10-09 | NCT07439510 | |
| Clinical Genetics Branch Eligibility Screening Survey | Abnormalities, Multiple, Bone Marrow Failure Disorders, Congenital Abnormalities, Congenital Bone Marrow Failure Syndromes, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Costello syndrome, Craniofacial Abnormalities, DNA repair disease, Fanconi anemia, Hemic and Lymphatic Diseases, Infant, Newborn, Diseases, Legius syndrome, Li-Fraumeni syndrome, Musculoskeletal Abnormalities, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Nutritional and Metabolic Diseases, Skin and Connective Tissue Diseases, Thoracic Neoplasms, anemia, aplastic anemia, bone marrow disorder, cardiofaciocutaneous syndrome, chordoma, hematologic disorder, hereditary disease, hereditary neoplastic syndrome, inherited aplastic anemia, lung neoplasm, melanocytic neoplasm, melanoma, metabolic disease, mixed neoplasm, musculoskeletal system disorder, neoplasm, neuroendocrine neoplasm, primitive neuroectodermal tumor, pulmonary blastoma, respiratory tract neoplasm, skin disorder, skin neoplasm, susceptibility to familial cutaneous melanoma | Not yet recruiting | Not stated | 2026-10-09 | NCT07005297 | |
| Effect of Sacubitril-Valsartan on Cardiac Structure and Function | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiovascular disorder, congenital heart disease, heart disorder | Recruiting | Phase 3 | 2026-10-09 | NCT06693674 | |
| Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With Critical CHD | Cardiovascular Abnormalities, Cognition Disorders, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiovascular disorder, cognitive disorder, congenital heart disease, heart disorder, psychiatric disorder | Active, not recruiting | Not applicable | 2026-10-09 | NCT06267430 | |
| A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment | Abnormalities, Multiple, Body Weight, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Froelich syndrome, Imprinting Disorders, Male Urogenital Diseases, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Overweight, Parkes Weber syndrome, Pathological Conditions, Signs and Symptoms, Prader-Willi syndrome, Signs and Symptoms, Urogenital Abnormalities, Urogenital Diseases, chromosomal disorder, disorder of sexual differentiation, endocrine system disorder, gonadal disorder, gonadal dysgenesis, hereditary disease, hypogonadism, intellectual disability, nervous system disorder, nutritional disorder, obesity disorder, overnutrition | Active, not recruiting | Phase 1 / Phase 2 | 2026-10-09 | NCT06239116 | |
| Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation. | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Lymphatic Abnormalities, Neoplasm, Lymphatic Tissue, Neoplasms by Histologic Type, cystic hygroma, lymphangioma, lymphatic system disorder, neoplasm | Recruiting | Phase 2 / Phase 3 | 2026-10-09 | NCT05948943 | |
| Merit WRAPSODY™ Endoprosthesis for Treatment of Stenosis or Occlusion (WRAP) | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Fistula, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Vascular Fistula, arteriovenous hemangioma/malformation, cardiovascular disorder, congenital arteriovenous fistula, vascular disorder, vascular malformation | Active, not recruiting | Not stated | 2026-10-09 | NCT05062291 | |
| Echocardiographic Assessment of Valvular Dysfunction in Children With CHD | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiovascular disorder, congenital heart disease, heart disorder, heart valve disorder | Not yet recruiting | Not stated | 2026-10-08 | NCT07866924 | |
| RVOT Stenting Versus Surgical RV-PA Conduit in Cyanotic Adults | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Ventricular Outflow Obstruction, Ventricular Outflow Obstruction, Right, cardiovascular disorder, congenital heart disease, heart disorder | Not yet recruiting | Not stated | 2026-10-08 | NCT07866911 | |
| UltraTrac for Cardiac Output Monitoring in Congenital Heart Disease | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiovascular disorder, congenital heart disease, heart disorder | Not yet recruiting | Not applicable | 2026-10-08 | NCT07866573 | |
| Migraine Headaches Elimination With Patent Foramen Ovale-Directed Therapy | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, congenital heart disease, headache disorder, heart disorder, heart septal defect, hypnic headache, migraine disorder, nervous system disorder, patent foramen ovale | Recruiting | Phase 3 | 2026-10-08 | NCT07629635 | |
| Observational Study of VYKAT™ XR in Patients With Prader-Willi Syndrome | Abnormalities, Multiple, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Imprinting Disorders, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Overweight, Prader-Willi syndrome, chromosomal disorder, hereditary disease, intellectual disability, nervous system disorder, nutritional disorder, obesity disorder, overnutrition | Enrolling by invitation | Not stated | 2026-10-08 | NCT07450664 | |
| Pediatric Evaluation and Registry for Liver Cholestasis in Canada | Abnormalities, Multiple, Alagille syndrome, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, bile duct disorder, biliary tract disorder, cardiovascular disorder, cholestasis, congenital heart disease, hereditary disease, intrahepatic cholestasis, liver disorder, progressive familial intrahepatic cholestasis type 1 | Recruiting | Not stated | 2026-10-08 | NCT07411716 | |
| A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY) | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiovascular disorder, central nervous system malformation, hereditary disease, hereditary sensory and autonomic neuropathy, hypertensive disorder, inherited neurodegenerative disorder, interstitial lung disease, lung disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, peripheral nervous system disorder, polyneuropathy, pulmonary arterial hypertension, pulmonary hypertension, respiratory system disorder, vascular disorder | Recruiting | Phase 2 | 2026-10-08 | NCT07175038 | |
| ES Catheter vs Cryoablation After Pectus Surgery | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Musculoskeletal Abnormalities, bone disorder, musculoskeletal system disorder, pectus excavatum | Recruiting | Not applicable | 2026-10-08 | NCT06682208 | |
| Long-Term SafEty and Clinical Outcomes of LivmArli in Patients in the United States (LEAP-US) | Abnormalities, Multiple, Alagille syndrome, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, bile duct disorder, biliary tract disorder, cardiovascular disorder, cholestasis, congenital heart disease, hereditary disease, intrahepatic cholestasis, liver disorder, progressive familial intrahepatic cholestasis type 1 | Recruiting | Not stated | 2026-10-08 | NCT06193928 | |
| Prospective Study for the Evaluation of the Cementless Anatomic Femoral Stem Minimax -Launay | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hip Dislocation, Congenital, Musculoskeletal Abnormalities, Necrosis, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, arthritic joint disease, arthropathy, autoimmune disease, avascular necrosis, bone disorder, bone fracture, connective tissue disorder, developmental dysplasia of the hip, immune system disorder, injury, musculoskeletal system disorder, osteonecrosis, rheumatic disorder, rheumatoid arthritis | Active, not recruiting | Not stated | 2026-10-08 | NCT06012656 | |
| French Registry of Children Treated With Norditropin® for Short Stature Associated With Noonan Syndrome | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Musculoskeletal Abnormalities, Noonan syndrome, Skin and Connective Tissue Diseases, cardiovascular disorder, congenital heart disease, connective tissue disorder, heart disorder, musculoskeletal system disorder | Enrolling by invitation | Not stated | 2026-10-08 | NCT05308927 | |
| Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Musculoskeletal Abnormalities, Neurologic Manifestations, Pain, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Postoperative Pain, Signs and Symptoms, Spinal Curvatures, bone disorder, musculoskeletal system disorder, pectus excavatum, scoliosis, vertebral column disorder | Active, not recruiting | Not applicable | 2026-10-08 | NCT04031716 | |
| Postoperative and Chronic Pain Genetic Spine and Pectus Surgery Study | Bone Diseases, Developmental, Chronic Pain, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Kyphosis, Musculoskeletal Abnormalities, Neurologic Manifestations, Pain, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Postoperative Pain, Signs and Symptoms, Spinal Curvatures, bone disorder, musculoskeletal system disorder, pectus excavatum, scoliosis, vertebral column disorder | Active, not recruiting | Not stated | 2026-10-08 | NCT02998138 | |
| Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma (MAC) | Anophthalmos, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Abnormalities, Eye Diseases, Hereditary, coloboma, eye disorder, microphthalmia | Recruiting | Not stated | 2026-10-08 | NCT01778543 | |
| MRI Study of Musculoskeletal Function | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, arthropathy, musculoskeletal system disorder, patellofemoral pain syndrome | Recruiting | Not stated | 2026-10-08 | NCT00051857 |