Chromosome Aberrations
Chromosome Aberrations
Explore linked clinical trials. Standard reference: MESH:M000440631 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies | B-cell neoplasm, Burkitt lymphoma, Chromosome Aberrations, DNA Virus Infections, Epstein-Barr virus infection, Hemic and Lymphatic Diseases, Herpesviridae infectious disease, Infections, Leukemia, B-Cell, Neoplasms by Histologic Type, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Philadelphia Chromosome, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Translocation, Genetic, Tumor Virus Infections, hematologic disorder, immune system disorder, immunoproliferative disorder, leukemia, lymphatic system disorder, lymphoid leukemia, lymphoma, lymphoproliferative syndrome, neoplasm, precursor B-cell acute lymphoblastic leukemia, viral infectious disease | Recruiting | Phase 1 / Phase 2 | 2026-09-30 | NCT05442515 | |
| Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy | Abnormalities, Multiple, Chromosome Aberrations, Chromosome Duplication, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Down syndrome, Neurobehavioral Manifestations, Neurologic Manifestations, Pathologic Processes, Pathological Conditions, Signs and Symptoms, aneuploidy, chromosomal disorder, hereditary disease, intellectual disability, nervous system disorder, trisomy | Recruiting | Not stated | 2026-09-09 | NCT01429389 | |
| A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP | Chromosome Aberrations, Chronic Disease, Disease Attributes, Hemic and Lymphatic Diseases, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Myeloproliferative Disorders, Neoplasms by Histologic Type, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Philadelphia Chromosome, Translocation, Genetic, bone marrow disorder, hematologic disorder, leukemia, myeloid leukemia, neoplasm | Active, not recruiting | Phase 3 | 2026-08-28 | NCT04971226 | |
| A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP) | Chromosome Aberrations, Chronic Disease, Disease Attributes, Hemic and Lymphatic Diseases, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Myeloproliferative Disorders, Neoplasms by Histologic Type, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Philadelphia Chromosome, Translocation, Genetic, bone marrow disorder, hematologic disorder, leukemia, myeloid leukemia, neoplasm | Active, not recruiting | Phase 3 | 2026-08-26 | NCT05456191 | |
| Study of Abnormally Fertilized Embryos | Chromosome Aberrations, Genital Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, infertility disorder, polyploidy, triploidy | Recruiting | Not stated | 2026-08-21 | NCT06940973 | |
| Non-Euploid Embryo Transfer (NEET) Registry | Chromosome Aberrations, Genital Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, aneuploidy, infertility disorder | Recruiting | Not stated | 2026-08-14 | NCT07036536 | |
| Biocollection in MyeloDysplastic Syndrome (P-MDS) | Chromosome Aberrations, Hemic and Lymphatic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, acute myeloid leukemia with multilineage dysplasia, bone marrow disorder, hematologic disorder, myelodysplastic syndrome, myelodysplastic syndrome associated with isolated del(5q), myelodysplastic syndrome with ring sideroblasts | Recruiting | Not applicable | 2026-06-25 | NCT04869683 | |
| The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment | 22q11.2 deletion syndrome, Abnormalities, Multiple, Cardiovascular Abnormalities, Chromosome Aberrations, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, DiGeorge syndrome, Down syndrome, Hemic and Lymphatic Diseases, Lymphatic Abnormalities, Musculoskeletal Abnormalities, Neurobehavioral Manifestations, Neurologic Manifestations, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Sex Chromosome Aberrations, Trisomy 18 Syndrome, aneuploidy, cardiovascular disorder, chromosomal disorder, congenital heart disease, endocrine system disorder, heart disorder, hereditary disease, hypoparathyroidism, intellectual disability, lymphatic system disorder, musculoskeletal system disorder, nervous system disorder, parathyroid gland disorder, trisomy 13, trisomy 18 | Recruiting | Not stated | 2026-06-12 | NCT07643896 | |
| Pregnancy and Developmental Outcomes After Transfer of Reportedly Aneuploid or Mosaic Embryos | Chromosome Aberrations, Pathologic Processes, Pathological Conditions, Signs and Symptoms, aneuploidy | Recruiting | Not applicable | 2026-04-24 | NCT04109846 | |
| MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies | Chromosome 7, monosomy, Chromosome Aberrations, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Infections, Neoplasm, Residual, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, RNA Virus Infections, acute leukemia, acute myeloid leukemia, anemia, beta thalassemia, bone marrow disorder, central nervous system leukemia, familial hemolytic anemia, hematologic disorder, hematopoietic and lymphoid system neoplasm, hemolytic anemia, hereditary disease, hereditary neoplastic syndrome, immune system disorder, immunoproliferative disorder, influenza, inherited hemoglobinopathy, inherited neurodegenerative disorder, juvenile myelomonocytic leukemia, leukemia, lymphatic system disorder, lymphoid leukemia, lymphoproliferative syndrome, myelodysplastic syndrome, myelodysplastic syndrome with excess blasts, myelodysplastic syndrome with single lineage dysplasia, myelodysplastic/myeloproliferative disease, myeloid leukemia, neoplasm, nerve sheath neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neurofibroma, neurofibromatosis, neurofibromatosis type 1, neuromuscular disease, peripheral nervous system disorder, respiratory system disorder, respiratory tract infectious disorder, thalassemia, viral infectious disease | Recruiting | Phase 2 | 2026-04-06 | NCT05735717 | |
| Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders | 22q11.2 deletion syndrome, Abnormalities, Multiple, Aortic Stenosis, Supravalvular, Brain Damage, Chronic, Brain Injuries, Traumatic, Cardiovascular Abnormalities, Cerebral Palsy, Athetoid, Chromosome Aberrations, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniocerebral Trauma, Craniofacial Abnormalities, DiGeorge syndrome, Down syndrome, Hemic and Lymphatic Diseases, Hypoxia, Hypoxia, Brain, Lymphatic Abnormalities, Musculoskeletal Abnormalities, Neurobehavioral Manifestations, Neurologic Manifestations, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Sex Chromosome Disorders, Signs and Symptoms, Signs and Symptoms, Respiratory, Williams syndrome, X-linked disease, aortic valve disorder, aortic valve stenosis, autism spectrum disorder, brain disorder, brain hypoxia - ischemia, brain injury, brain ischemia, cardiovascular disorder, central nervous system disorder, cerebral palsy, cerebral palsy spastic hemiplegic, cerebrovascular disorder, chromosomal disorder, congenital heart disease, developmental disability, endocrine system disorder, fragile X syndrome, heart disorder, heart valve disorder, hereditary disease, hypoparathyroidism, inherited neurodegenerative disorder, injury, intellectual disability, lymphatic system disorder, musculoskeletal system disorder, nervous system disorder, nervous system injury, neurodevelopmental disorder, parathyroid gland disorder, perinatal asphyxia, pervasive developmental disorder, psychiatric disorder, vascular disorder | Recruiting | Not stated | 2026-03-25 | NCT07493096 | |
| Pilot Study of Discarded Blastocysts | Chromosome Aberrations, Genital Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, aneuploidy, infertility disorder | Not yet recruiting | Not stated | 2026-02-24 | NCT07429097 | |
| Embryo Assessment Utilizing Timelapse Imaging in Conjunction With Preimplantation Genetic Testing for Aneuploidy With Next Generation Sequencing | Chromosome Aberrations, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Male Urogenital Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, aneuploidy, female infertility, female reproductive system disorder, infertility disorder, long QT syndrome 3, male infertility, male reproductive system disorder, paroxysmal familial ventricular fibrillation | Enrolling by invitation | Not stated | 2026-01-29 | NCT06419127 | |
| To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That Develop to the Point That They Are Able to be Transferred) in IVF Cycles. | Chromosome Aberrations, Genital Diseases, Male Urogenital Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, aneuploidy, infertility disorder, male infertility, male reproductive system disorder | Active, not recruiting | Not applicable | 2026-01-27 | NCT07369362 | |
| Clinical and Genetic Aspects in Fetuses and Children With Sex Chromosome Disorders | 47,XYY syndrome, Abnormal Karyotype, Cardiovascular Abnormalities, Chromosome Aberrations, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Klinefelter syndrome, Male Urogenital Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Sex Chromosome Aberrations, Sex Chromosome Disorders, Turner syndrome, Urogenital Abnormalities, Urogenital Diseases, cardiovascular disorder, chromosomal disorder, congenital heart disease, disorder of sexual differentiation, endocrine system disorder, gonadal disorder, gonadal dysgenesis, heart disorder, hereditary disease, hypogonadism, sex chromosome disorder of sex development, trisomy X | Enrolling by invitation | Not stated | 2026-01-14 | NCT07341412 | |
| Chromosome 18 Clinical Research Center | Bone Diseases, Developmental, Bone Diseases, Endocrine, Chromosome Aberrations, Dwarfism, Pathologic Processes, Pathological Conditions, Signs and Symptoms, bone disorder, brain disorder, central nervous system disorder, endocrine system disorder, hypopituitarism, hypothalamic disorder, musculoskeletal system disorder, nervous system disorder, pituitary dwarfism, pituitary gland disorder | Recruiting | Not stated | 2026-01-06 | NCT00227253 | |
| Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos | Chromosome Aberrations, Pathologic Processes, Pathological Conditions, Signs and Symptoms, aneuploidy | Recruiting | Not stated | 2025-11-12 | NCT07227116 | |
| A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer | Chromosomal Instability, Chromosome Aberrations, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Genomic Instability, Head and Neck Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, Urogenital Diseases, Urogenital Neoplasms, breast disorder, breast neoplasm, carcinoma, endometrium neoplasm, epithelial neoplasm, female reproductive system disorder, female reproductive system neoplasm, head and neck squamous cell carcinoma, neoplasm, ovarian carcinosarcoma, skin disorder, squamous cell carcinoma, triple-negative breast carcinoma, uterine carcinosarcoma, uterine disorder | Recruiting | Phase 1 / Phase 2 | 2025-11-04 | NCT05902988 | |
| Detection of Genetic Markers of Lung Cancer | Carcinogenesis, Chromosome Aberrations, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Thoracic Neoplasms, lung cancer, lung disorder, lung neoplasm, neoplasm, respiratory system disorder, respiratory tract neoplasm | Recruiting | Not stated | 2025-10-24 | NCT00280202 | |
| A Study of Sovilnesib in Subjects With Ovarian Cancer | Adnexal Diseases, Chromosomal Instability, Chromosome Aberrations, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Genomic Instability, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, Urogenital Neoplasms, fallopian tube cancer, fallopian tube disorder, fallopian tube neoplasm, female reproductive system disorder, female reproductive system neoplasm, neoplasm, primary peritoneal carcinoma | Active, not recruiting | Phase 1 | 2025-10-20 | NCT06084416 | |
| Chromosomal Abnormalities in Patients With Congenital Heart Disease at Assiut University Children's Hospital | Cardiovascular Abnormalities, Chromosome Aberrations, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Pathologic Processes, Pathological Conditions, Signs and Symptoms, cardiovascular disorder, congenital heart disease, heart disorder | Not yet recruiting | Not stated | 2025-10-02 | NCT07204509 | |
| GEM: Impact of a Video Education Tool on Decisional Conflict Among Prenatal Patients | Chromosome Aberrations, Pathologic Processes, Pathological Conditions, Signs and Symptoms, aneuploidy | Active, not recruiting | Not applicable | 2025-09-18 | NCT06771453 | |
| Prevalence of Translocation Phenotyping in Children With Down Syndrome and Their Parents | Abnormalities, Multiple, Chromosome Aberrations, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Down syndrome, Neurobehavioral Manifestations, Neurologic Manifestations, Pathologic Processes, Pathological Conditions, Signs and Symptoms, chromosomal disorder, hereditary disease, intellectual disability, nervous system disorder, translocation Down syndrome | Not yet recruiting | Not stated | 2025-09-16 | NCT07175168 | |
| Structural Chromosome Rearrangements and Brain Disorders | Chromosome Aberrations, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Disease Attributes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Rare Diseases, hereditary disease | Enrolling by invitation | Not stated | 2025-09-04 | NCT06072079 | |
| Prenatal Genetics Chatbot Trial: Prenatal GENEie | Chromosome Aberrations, Pathologic Processes, Pathological Conditions, Signs and Symptoms, aneuploidy | Not yet recruiting | Not applicable | 2025-07-28 | NCT07077707 |