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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Biomechanical Characterization of Skin Properties Using Impact Based-Analysis Method (IBAM)Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, disease, melanocytic neoplasm, melanoma, neoplasm, neuroendocrine neoplasm, primitive neuroectodermal tumor, skin carcinoma, skin disorder, skin neoplasmNot yet recruitingNot stated2026-10-06NCT07861022
SPECTRA: Intraoperative Hyperspectral Imaging for Prostate CancerMargins of Excision, Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, Positive Surgical MarginsRecruitingNot applicable2026-09-17NCT07826858
Impact of Systematic Shaving on MarginsMargins of Excision, Morphological and Microscopic Findings, Negative Surgical Margins, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderRecruitingNot applicable2026-09-17NCT05782686
Defining the Ablative Dose for Y-90 TAREDigestive System Diseases, Digestive System Neoplasms, Liver Neoplasms, Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Histologic Type, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, adenocarcinoma, carcinoma, epithelial neoplasm, hepatocellular carcinoma, liver disorder, neoplasmRecruitingPhase 22026-09-15NCT07586046
Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin ReductionMargins of Excision, Morphological and Microscopic Findings, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, brain disorder, central nervous system cancer, central nervous system disorder, neoplasm, nervous system disorderRecruitingPhase 22026-09-08NCT07132190
Ultrasound-Guided Versus Standard Margin Selection in Ileocecal Resection of Terminal Ileal CDCrohn disease, Digestive System Diseases, Margins of Excision, Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, digestive system disorder, gastroenteritis, inflammatory bowel disease, intestinal disorderRecruitingNot applicable2026-08-27NCT07680283
Single Fraction Stereotactic Body Radiation Therapy After Surgery in Treating Patients With Non-small Cell Lung CancerMargins of Excision, Morphological and Microscopic Findings, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, Positive Surgical Margins, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmActive, not recruitingPhase 12026-08-24NCT04073745
Individualized Primary Clinical Target Volume Based on Margin Expansion for Nasopharyngeal CarcinomaMargins of Excision, Morphological and Microscopic Findings, Pathological Conditions, Signs and SymptomsRecruitingPhase 32026-08-19NCT07661771
Efficacy and Safety of Topical Timolol in Secondary Intention Surgical Wounds HealingMargins of Excision, Morphological and Microscopic Findings, Pathological Conditions, Signs and SymptomsNot yet recruitingPhase 22026-08-18NCT07384767
Intra-operative Detection of Positive Margins and Lymph Nodes in Breast SurgeryMargins of Excision, Morphological and Microscopic Findings, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, neoplasm, skin disorderRecruitingNot stated2026-07-30NCT06977698
Intraoperative Molecular Imaging Using ICG for Head and Neck TumorsHead and Neck Neoplasms, Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Histologic Type, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, carcinoma, epithelial neoplasm, head and neck squamous cell carcinoma, neoplasm, squamous cell carcinomaRecruitingPhase 22026-07-07NCT07149207
A Novel Intraoperative Fluorescence-guided System for Evaluating Margins During Breast-conserving Surgery for Breast CancerMargins of Excision, Morphological and Microscopic Findings, Pathological Conditions, Signs and SymptomsRecruitingNot applicable2026-06-29NCT07352930
Spectroscopic Analysis of Tongue Tumor Samples.Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Histologic Type, Pathological Conditions, Signs and Symptoms, carcinoma, epithelial neoplasm, neoplasm, squamous cell carcinoma, squamous cell neoplasmRecruitingNot stated2026-06-15NCT05104619
Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid TumorsAdnexal Diseases, Digestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Head and Neck Neoplasms, Liver Neoplasms, Male Urogenital Diseases, Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Histologic Type, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, Thoracic Neoplasms, Urogenital Diseases, Urogenital Neoplasms, adenocarcinoma, benign urinary system neoplasm, breast disorder, breast neoplasm, bronchial neoplasm, bronchogenic carcinoma, carcinoma, digestive system disorder, digestive system neoplasm, endocrine system disorder, epithelial neoplasm, female reproductive system disorder, female reproductive system neoplasm, gastric cancer, gastric neoplasm, gonadal disorder, head and neck squamous cell carcinoma, kidney cancer, kidney disorder, liver cancer, liver disorder, lung disorder, lung neoplasm, male reproductive organ cancer, male reproductive system disorder, malignant endocrine neoplasm, neoplasm, non-small cell lung carcinoma, ovarian cancer, ovarian disorder, prostate cancer, prostate disorder, renal cell carcinoma, respiratory system disorder, respiratory tract neoplasm, skin disorder, small cell lung carcinoma, squamous cell carcinoma, stomach disorder, triple-negative breast carcinoma, urinary system disorderRecruitingPhase 12026-06-10NCT07517198
PIRe 2.0: A Stepped-Care Model for Involving Relatives Across SectorsBrain Injuries, Traumatic, Craniocerebral Trauma, Injuries, Acute Brain, Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, astrocytoma (excluding glioblastoma), brain disorder, brain injury, cardiovascular disorder, central nervous system cancer, central nervous system disorder, cerebrovascular disorder, epithelial neoplasm, glioblastoma, glioma, injury, neoplasm, nervous system disorder, nervous system injury, neuroepithelial neoplasm, primitive neuroectodermal tumor, stroke disorder, vascular disorderNot yet recruitingNot applicable2026-05-19NCT07590726
A Study to Evaluate the Performance of Confocal Microscopy to Detect Positive Margins During Radical ProstatectomyGenital Diseases, Male Urogenital Diseases, Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Histologic Type, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, Urogenital Neoplasms, adenocarcinoma, carcinoma, epithelial neoplasm, male reproductive organ cancer, male reproductive system disorder, neoplasm, prostate cancer, prostate disorderRecruitingNot applicable2026-05-18NCT07541911
Infiltration Pattern of Locally Advanced ESCCDigestive System Diseases, Digestive System Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Histologic Type, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, carcinoma, digestive system disorder, digestive system neoplasm, epithelial neoplasm, esophageal disorder, esophageal squamous cell carcinoma, neoplasm, squamous cell carcinoma, squamous cell neoplasmEnrolling by invitationNot stated2026-05-05NCT07567716
Margin Intraoperative CT Feedback Feedback StudyMargins of Excision, Morphological and Microscopic Findings, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Thoracic Neoplasms, disease, lung disorder, lung neoplasm, neoplasm, respiratory system disorder, respiratory tract neoplasmActive, not recruitingNot applicable2026-04-28NCT07242053
HISMAR: Intraoperative Margin Assessment Using the Histolog® Scanner to Reduce Reoperation in Breast-Conserving SurgeryCarcinoma, Lobular, Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Ductal, Lobular, and Medullary, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, adenocarcinoma, breast cancer, breast carcinoma in situ, breast disorder, breast neoplasm, carcinoma, ductal breast carcinoma in situ, epithelial neoplasm, in situ carcinoma, invasive lobular breast carcinoma, neoplasm, skin disorderNot yet recruitingNot applicable2026-04-14NCT07527468
Intraoperative Use of I.V. Sodium Fluorescein in Suspected CNS TumorsMargins of Excision, Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, neoplasmRecruitingNot stated2026-02-11NCT07233954
Impact of Preoperative High-Frequency Ultrasound Cutaneous Lesion Extent Assessment on Excision Margin Positivity in Head and Neck Skin Cancer, and the Relationship Between Preoperative Assessment Methods, Inadequate Excision Margins, and Tumor RecurrenceDisease Attributes, Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Histologic Type, Neoplasms by Site, Non-Melanoma Skin Neoplasms, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, Skin and Connective Tissue Diseases, basal cell carcinoma, basal cell neoplasm, carcinoma, epithelial neoplasm, neoplasm, skin basal cell carcinoma, skin disorder, skin neoplasm, squamous cell carcinoma, squamous cell neoplasmNot yet recruitingNot stated2026-01-23NCT07361666
A Prospective Clinical Study Investigating the Use of the Histolog Scanner for Intraoperative Assessment of Surgical Margins in Patients Undergoing Breast-conserving Surgery for Histologically Confirmed Breast Cancer. The Histolog Scanner Operates on the Principle of Confocal MicroscopMargins of Excision, Morphological and Microscopic Findings, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderNot yet recruitingNot stated2026-01-14NCT07341542
Performance of 18F-FDG Micro-PET-CT in the Assessment of Surgical Margins in Head and Neck CancerHead and Neck Neoplasms, Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, neoplasmRecruitingNot applicable2025-12-16NCT07285564
Feasibility of Timesaving When Using Histolog Confocal Laser Endomicroscopy for Margin Assessment in Prostatectomy SpecimenGenital Diseases, Male Urogenital Diseases, Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, Urogenital Neoplasms, male reproductive organ cancer, male reproductive system disorder, neoplasm, prostate cancer, prostate disorderRecruitingNot applicable2025-10-07NCT07141121
Comparative Research on the Accuracy of Margin Interpretation in Breast-Conserving Surgery for Breast Cancer: Cell Microscopic Imaging and Standard Frozen PathologyMargins of Excision, Morphological and Microscopic Findings, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, breast carcinoma, breast disorder, breast neoplasm, neoplasm, skin disorderNot yet recruitingNot applicable2025-06-19NCT07029646