Immunoglobulin G4-Related Disease
Immunoglobulin G4-Related Disease
Explore linked clinical trials. Standard reference: MESH:M00064139237 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Study to Assess Safety, Efficacy and Persistence of ACE1831, in Subjects With IgG4-Related Disease | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Recruiting | Phase 1 / Phase 2 | 2026-10-02 | NCT07061938 | |
| Comparative Autoantibody and Immunologic Cell Marker Study | AIDS, Blood-Borne Infections, Chronic Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cytopenia, DNA Virus Infections, Digestive System Diseases, Disease Attributes, Epstein-Barr virus infection, Flaviviridae infectious disease, Genital Diseases, Guillain-Barre syndrome, HIV infectious disease, Hemic and Lymphatic Diseases, Hemorrhage, Herpesviridae infectious disease, Immunoglobulin G4-Related Disease, Infections, Inflammation, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Post-Infectious Disorders, Purpura, Thrombocytopenic, Idiopathic, RNA Virus Infections, Sepsis, Signs and Symptoms, Sjogren syndrome, Skin Manifestations, Skin and Connective Tissue Diseases, Slow Virus Diseases, Stomatognathic Diseases, Systemic Inflammatory Response Syndrome, Tumor Virus Infections, Undifferentiated Connective Tissue Diseases, Urogenital Diseases, Xerostomia, arthritic joint disease, arthropathy, autoimmune disease, autoimmune disorder of the nervous system, autoimmune lymphoproliferative syndrome, blood coagulation disease, blood platelet disease, connective tissue disorder, demyelinating disease, diffuse scleroderma, dry eye syndrome, eye disorder, graft versus host disease, hematologic disorder, hemorrhagic disease, hepatitis, hepatitis C virus infection, hereditary disease, immune system disorder, immunoproliferative disorder, inborn error of immunity, infectious disease, juvenile idiopathic arthritis, lacrimal apparatus disorder, lentivirus infection, liver disorder, lymphatic system disorder, lymphoproliferative syndrome, mouth disorder, muscle tissue disorder, musculoskeletal system disorder, myositis disease, nervous system disorder, neuromuscular disease, peripheral nervous system disorder, polyneuropathy, polyradiculoneuropathy, purpura, rheumatic disorder, rheumatoid arthritis, salivary gland disorder, sexually transmitted disease, skin disorder, systemic lupus erythematosus, systemic sclerosis, thrombocytopenia, thrombocytopenic purpura, thrombotic microangiopathy, uterine carcinosarcoma, viral hepatitis, viral infectious disease, viral sexually transmitted disease | Enrolling by invitation | Not stated | 2026-10-01 | NCT02422875 | |
| A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Recruiting | Phase 3 | 2026-09-23 | NCT07190196 | |
| the Safety and Efficacy of Targeted BCMA In Vivo LV Injection for Recurrent or Refractory Autoimmune Diseases | Disease Attributes, Immunoglobulin G4-Related Disease, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, Skin and Connective Tissue Diseases, anti-neutrophil cytoplasmic antibody-associated vasculitis, autoimmune disease, cardiovascular disorder, connective tissue disorder, immune system disorder, muscle tissue disorder, musculoskeletal system disorder, myositis disease, necrotizing vasculitis, nervous system disorder, neuromuscular disease, skin disorder, skin vascular disease, systemic lupus erythematosus, systemic sclerosis, vascular disorder, vasculitis | Active, not recruiting | Early phase 1 | 2026-09-17 | NCT07339540 | |
| Nebulized UC-EVs for Recurrent or Refractory IMIDs With Lung Involvement | Immunoglobulin G4-Related Disease, Skin and Connective Tissue Diseases, autoimmune disease, connective tissue disorder, immune system disorder, skin disorder, systemic sclerosis | Not yet recruiting | Early phase 1 | 2026-09-08 | NCT07806045 | |
| BCT301 in Treating Refractory/Recurrent IgG4-related Disease | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Not yet recruiting | Not applicable | 2026-08-31 | NCT07793903 | |
| Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Inebilizumab in Pediatric Participants With IgG4-RD | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Not yet recruiting | Phase 2 | 2026-08-27 | NCT07222553 | |
| A Study of Efgartigimod in Patients With IgG4-Related Disease | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Active, not recruiting | Phase 2 | 2026-07-23 | NCT07025330 | |
| Efficacy and Safety of Lenalidomide in Patients With IgG4-Related Disease | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Not yet recruiting | Phase 3 | 2026-07-22 | NCT07719543 | |
| The BCMA/CD19 Dual Targeted CAR-T Cell in Participants With Autoimmune Kidney Diseases | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Immunoglobulin G4-Related Disease, Male Urogenital Diseases, Skin and Connective Tissue Diseases, Urogenital Diseases, anti-neutrophil cytoplasmic antibody-associated vasculitis, autoimmune disease, cardiovascular disorder, connective tissue disorder, glomerulonephritis, immune system disorder, kidney disorder, lupus nephritis, necrotizing vasculitis, nephritis, skin disorder, skin vascular disease, systemic lupus erythematosus, urinary system disorder, vascular disorder, vasculitis | Recruiting | Phase 1 | 2026-07-06 | NCT06285279 | |
| A Study of IMM0306 in IgG4-Related Disease | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Not yet recruiting | Phase 2 / Phase 3 | 2026-06-02 | NCT07621939 | |
| Validation of the Odesa Criteria 2026 for Autoimmune Pancreatitis | Chronic Disease, Digestive System Diseases, Digestive System Neoplasms, Disease Attributes, Immunoglobulin G4-Related Disease, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, autoimmune disease, autoimmune pancreatitis, chronic pancreatitis, endocrine system disorder, immune system disorder, malignant endocrine neoplasm, malignant pancreatic neoplasm, neoplasm, pancreas disorder, pancreatic neoplasm, pancreatitis | Recruiting | Not stated | 2026-05-28 | NCT07536841 | |
| A Study to Evaluate MTM-H-001 Injection in Adult Patients With B-Cell-Related Autoimmune Diseases | CNS demyelinating autoimmune disease, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Immunoglobulin G4-Related Disease, Male Urogenital Diseases, Neoplasms by Site, Paraneoplastic Syndromes, Nervous System, Skin and Connective Tissue Diseases, Urogenital Diseases, arthritic joint disease, arthropathy, autoimmune disease, autoimmune disorder of the nervous system, connective tissue disorder, demyelinating disease, glomerulonephritis, immune system disorder, kidney disorder, lupus nephritis, multiple sclerosis, musculoskeletal system disorder, myasthenia gravis, neoplasm, nephritis, nervous system disorder, neurodegenerative disease, neuromuscular disease, neuromuscular junction disease, paraneoplastic syndrome, rheumatic disorder, rheumatoid arthritis, systemic lupus erythematosus, urinary system disorder | Not yet recruiting | Not applicable | 2026-05-18 | NCT07593911 | |
| Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases | Behcet disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Immunoglobulin G4-Related Disease, Skin and Connective Tissue Diseases, Stomatognathic Diseases, acquired idiopathic inflammatory myopathy, anterior uveitis, autoimmune disease, cardiovascular disorder, eye disorder, hereditary disease, hereditary periodic fever syndrome, hereditary skin disorder, immune system disorder, mouth disorder, muscle tissue disorder, musculoskeletal system disorder, myositis disease, nervous system disorder, neuromuscular disease, panuveitis, skin disorder, skin vascular disease, uveal disorder, uveitis, vascular disorder, vasculitis | Recruiting | Phase 2 | 2026-05-12 | NCT06285539 | |
| The Investigators Will Evaluate the Diagnostic Performance of [18F]-AlF-FAPI-74 PET/CT in Inflammatory Disorders and Compare it With the Current Gold Standard for Inflammation, FDG PET/CT, in Three Patient Cohort: Patients Presenting With Fever of Unknown Origin, IgG4-RD and AxSpA. | Body Temperature Changes, Fever, Fever of Unknown Origin, Immunoglobulin G4-Related Disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autoimmune disease, immune system disorder | Recruiting | Phase 2 / Phase 3 | 2026-04-17 | NCT07535554 | |
| Treatment Strategies for IgG4-RD Patients With Superficial Organ Involvement | Disease Attributes, Immunoglobulin G4-Related Disease, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, autoimmune disease, immune system disorder | Recruiting | Not applicable | 2026-04-07 | NCT05789030 | |
| A Phase 3 Study of Obexelimab in Patients With IgG4-Related Disease | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Active, not recruiting | Phase 3 | 2026-02-04 | NCT05662241 | |
| Institutional Registry of Rare Diseases | Abnormalities, Multiple, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, Cardiovascular Abnormalities, Ciliopathies, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cushing syndrome, Digestive System Abnormalities, Digestive System Diseases, Disease Attributes, Eosinophilia, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Gaucher disease, Hemic and Lymphatic Diseases, Hereditary Complement Deficiency Diseases, Hirschsprung disease, Hypersensitivity, Delayed, Hypersensitivity, Immediate, Immunoglobulin G4-Related Disease, Imprinting Disorders, Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Lysosomal Storage Diseases, Nervous System, Male Urogenital Diseases, Mast Cell Activation Disorders, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Multiple Primary, Neoplasms, Nerve Tissue, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Overweight, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Prader-Willi syndrome, Primary Immunodeficiency Diseases, Rare Diseases, Skin Abnormalities, Skin and Connective Tissue Diseases, Urogenital Abnormalities, Urogenital Diseases, Wilson disease, adrenal gland disorder, adrenal gland hyperfunction, adrenogenital syndrome, amyloidosis, angioedema, angiomatosis, aortic valve disorder, aortic valve stenosis, autoimmune disease, basal ganglia disorder, brain disorder, cardiomyopathy, cardiovascular disorder, central nervous system disorder, chromosomal disorder, colonic disorder, congenital adrenal hyperplasia, connective tissue neoplasm, demyelinating disease, digestive system disorder, disorder of sexual differentiation, ectodermal dysplasia syndrome, endocrine system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, gonadal disorder, heart disorder, heart valve disorder, hematologic disorder, hemorrhagic disease, hereditary angioedema, hereditary disease, hereditary hemorrhagic telangiectasia, hereditary neoplastic syndrome, hereditary skin disorder, hypertensive disorder, hypertrophic cardiomyopathy, immune system disorder, inborn error of immunity, inborn errors of metabolism, inborn metal metabolism disorder, inflammatory bowel disease, inherited neurodegenerative disorder, intellectual disability, intestinal disorder, leukocyte disorder, liver disorder, lung disorder, lymphatic system disorder, lymphoproliferative syndrome, lysosomal lipid storage disorder, lysosomal storage disease, malignant endocrine neoplasm, mastocytosis, megacolon, metabolic disease, movement disorder, multiple endocrine neoplasia, neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neuroendocrine neoplasm, nutritional disorder, obesity disorder, overnutrition, paraganglioma, pheochromocytoma, primitive neuroectodermal tumor, proteostasis deficiencies, pulmonary hypertension, respiratory system disorder, sarcoidosis, skin disorder, skin vascular disease, sphingolipidosis, steroid inherited metabolic disorder, subvalvular aortic stenosis, telangiectasis, urticaria, vascular disorder, vascular hemostatic disease, vascular malformation, von Hippel-Lindau disease | Recruiting | Not stated | 2026-01-14 | NCT06573723 | |
| A Randomized Controlled Study of the Efficacy and Safety of Lenalidomide in the Treatment of Active IgG4-related Disease | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Recruiting | Phase 2 / Phase 3 | 2025-12-30 | NCT07068165 | |
| An Exploratory Clinical Study on the Safety and Efficacy of CD19/BCMA CAR-NK in the Treatment of Relapsed and Refractory IgG4-related Disease | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Not yet recruiting | Early phase 1 | 2025-12-23 | NCT07298590 | |
| A Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Active, not recruiting | Phase 3 | 2025-12-11 | NCT04540497 | |
| Exploratory Study of Anti-BCMA-CD19 CAR-T Cell Therapy in Relapsed or Refractory IgG4-Related Disease | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Recruiting | Phase 2 | 2025-09-03 | NCT07148791 | |
| A Study on the Effect of MRD Detected by FAPI PET / CT on the Recurrence of IgG4-RD | Immunoglobulin G4-Related Disease, autoimmune disease, immune system disorder | Recruiting | Not applicable | 2025-08-05 | NCT07104058 | |
| A Clinical Study of YTS109 Cell in R/R Autoimmune Diseases | Immunoglobulin G4-Related Disease, Skin and Connective Tissue Diseases, anti-neutrophil cytoplasmic antibody-associated vasculitis, antiphospholipid syndrome, arthritic joint disease, arthropathy, autoimmune disease, cardiovascular disorder, connective tissue disorder, immune system disorder, muscle tissue disorder, musculoskeletal system disorder, myositis disease, necrotizing vasculitis, nervous system disorder, neuromuscular disease, rheumatic disorder, rheumatoid arthritis, skin disorder, skin vascular disease, systemic lupus erythematosus, systemic sclerosis, vascular disorder, vasculitis | Recruiting | Phase 1 | 2025-07-14 | NCT06978647 | |
| UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases | Hemic and Lymphatic Diseases, Immunoglobulin G4-Related Disease, Neoplasms by Site, Paraneoplastic Syndromes, Nervous System, Skin and Connective Tissue Diseases, anemia, anti-neutrophil cytoplasmic antibody-associated vasculitis, autoimmune disease, autoimmune disorder of the nervous system, autoimmune hemolytic anemia, cardiovascular disorder, connective tissue disorder, hematologic disorder, hemolytic anemia, immune system disorder, muscle tissue disorder, musculoskeletal system disorder, myasthenia gravis, myositis disease, necrotizing vasculitis, neoplasm, nervous system disorder, neurodegenerative disease, neuromuscular disease, neuromuscular junction disease, paraneoplastic syndrome, skin disorder, skin vascular disease, systemic lupus erythematosus, systemic sclerosis, vascular disorder, vasculitis | Not yet recruiting | Phase 1 | 2025-05-18 | NCT06978738 |