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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer PatientsDigestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal carcinoma, rectal disorder, rectal neoplasmRecruitingNot applicable2026-10-06NCT06424522
Transanal Irrigation for the Management of Early Low Anterior Resection Syndrome (LARS)Digestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal cancer, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal disorderNot yet recruitingNot applicable2026-08-18NCT07219745
Early Implementation of Sacral Neuromodulation in Patients With Low Anterior Resection Syndrome.Digestive System Diseases, Low Anterior Resection Syndrome, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, digestive system disorder, intestinal disorder, rectal disorderNot yet recruitingNot applicable2026-08-12NCT07761884
Aerobic Exercise and Guided Imagery in Low Anterior Resection SyndromeDigestive System Diseases, Digestive System Neoplasms, Fecal Incontinence, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Signs and Symptoms, Signs and Symptoms, Digestive, colonic disorder, colorectal neoplasm, constipation disorder, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal cancer, rectal disorder, rectal neoplasmRecruitingNot applicable2026-07-29NCT07732894
Autologous Fecal Microbiota Transplantation for Anal Function Recovery After Ileostomy Reversal in Rectal CancerDigestive System Diseases, Digestive System Neoplasms, Fecal Incontinence, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, diversion colitis, intestinal disorder, neoplasm, rectal cancer, rectal disorder, rectal neoplasmActive, not recruitingNot applicable2026-07-17NCT07711509
Evaluating the Optimal Timing of Trans-Anal Irrigation for Low Anterior Resection Syndrome Post-rectal Cancer SurgeryDigestive System Diseases, Digestive System Neoplasms, Fecal Incontinence, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Signs and Symptoms, Signs and Symptoms, Digestive, colonic disorder, colorectal neoplasm, constipation disorder, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal disorder, rectal neoplasmNot yet recruitingNot applicable2026-07-10NCT07696689
Efficacy and Safety of Transcutaneous Posterior Tibial Nerve Stimulation on Fecal Continence in Patients Undergoing Surgery for Rectal NeoplasiaDigestive System Diseases, Digestive System Neoplasms, Ejaculatory Dysfunction, Fecal Incontinence, Genital Diseases, Low Anterior Resection Syndrome, Male Urogenital Diseases, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Urogenital Diseases, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, male reproductive system disorder, neoplasm, physiological sexual disorder, rectal disorder, rectal neoplasmRecruitingNot applicable2026-06-08NCT07632196
Transanal Irrigation for the Management of LARSDigestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal cancer, rectal disorder, rectal neoplasmActive, not recruitingNot applicable2026-06-02NCT05007015
The Effects of Kegel Exercise Combined With Biofeedback Therapy on Bowel Function Recovery, Emotional Distress, and Quality of Life in Patients Following Low Anterior Resection for Rectal CancerDigestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal cancer, rectal disorder, rectal neoplasmEnrolling by invitationNot applicable2026-05-11NCT07253298
Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.Digestive System Diseases, Digestive System Neoplasms, Fatigue, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Signs and Symptoms, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, injury, intestinal disorder, neoplasm, radiation injury, rectal cancer, rectal disorder, rectal neoplasmRecruitingPhase 2 / Phase 32026-05-11NCT06758830
Understanding and Tailored Treatment of Low Anterior Resection SyndromeDigestive System Diseases, Elimination Disorders, Encopresis, Low Anterior Resection Syndrome, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Signs and Symptoms, Signs and Symptoms, Digestive, colonic disorder, digestive system disorder, intestinal disorder, psychiatric disorder, rectal disorderRecruitingNot stated2026-05-07NCT07573371
Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & SurveillanceDigestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal cancer, rectal disorder, rectal neoplasmRecruitingPhase 32026-05-06NCT06936774
Antegrade Intestinal Fluid Reinfusion for Prevention of Low Anterior Resection Syndrome After Low Anterior Resection: a Single-Center, Prospective Randomized Controlled Trial.Digestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal cancer, rectal disorder, rectal neoplasmRecruitingPhase 2 / Phase 32026-04-17NCT07537998
Personalized Care Pathways for Bowel Symptoms in Rectal Cancer patients_development of E-diaryDigestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal cancer, rectal disorder, rectal neoplasmRecruitingNot applicable2026-04-15NCT06274190
Personalized Care Pathways for Bowel Symptoms in Rectal Cancer Patients_contributing Factors (Treatable)Digestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal cancer, rectal disorder, rectal neoplasmRecruitingNot applicable2026-01-23NCT06914245
ProLARS Trial: Prospective Longitudinal Follow-up of Low Anterior Resection Syndrome (LARS) and COREFO Score After Rectum Surgery in Patients Undergoing Upfront Surgery or Different Neo-adjuvant Treatment RegimensDigestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal disorder, rectal neoplasm, rectum adenocarcinomaRecruitingNot applicable2026-01-14NCT07339904
Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal CancerAnastomotic Leak, Digestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal disorder, rectal neoplasmRecruitingNot applicable2025-12-18NCT05943444
Transanal Irrigation for Low Anterior Resection Syndrome.Digestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal disorder, rectal neoplasmActive, not recruitingNot applicable2025-09-16NCT05245331
The Efficacy of Antegrade and Retrograde Enemas Management in Low Anterior Resection Syndrome and Improving the Rate of Ileostomy ReversalDigestive System Diseases, Low Anterior Resection Syndrome, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, digestive system disorder, intestinal disorder, rectal disorderNot yet recruitingNot applicable2025-07-24NCT07082699
Effect of Thread Embedding Acupuncture on Postoperative Ileus Recovery After Colorectal Cancer Surgery: A Multicenter Randomized Controlled TrialDigestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal cancer, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal disorderRecruitingNot applicable2025-07-18NCT07071987
Knowledge-enhanced Digital Intervention to Prevent Low Anterior Resection SyndromeDigestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal disorder, rectal neoplasmNot yet recruitingNot applicable2025-06-27NCT07041515
A Randomised Clinical Investigation to Assess Efficacy of Low Volume Transanal Irrigation by Qufora® IrriSedo MiniGo Versus Conservative Treatment for Low Anterior Resection Syndrome PatientsDigestive System Diseases, Digestive System Neoplasms, Low Anterior Resection Syndrome, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal cancer, rectal disorder, rectal neoplasmRecruitingNot stated2025-04-11NCT06923150
Retrograde and Antegrade Enema for Prevention of LARS After LAR: a Randomized Controlled TrialDigestive System Diseases, Low Anterior Resection Syndrome, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, digestive system disorder, intestinal disorder, rectal disorderNot yet recruitingNot applicable2025-03-30NCT06717854
Transanal Irrigation for Low Anterior Resection SyndromeDigestive System Diseases, Dyssomnias, Low Anterior Resection Syndrome, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Sleep Disorders, Intrinsic, colonic disorder, digestive system disorder, insomnia, intestinal disorder, nervous system disorder, psychiatric disorder, rectal disorder, sleep-wake disorderNot yet recruitingNot applicable2025-01-28NCT06796296
Fecal Microbiota Transplantation in the Treatment of Major LARSDigestive System Diseases, Low Anterior Resection Syndrome, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, colonic disorder, digestive system disorder, intestinal disorder, rectal disorderNot yet recruitingNot applicable2024-06-26NCT06475430