Genetic Risk Score
Genetic Risk Score
Explore linked clinical trials. Standard reference: MESH:M00076222737 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Polygenic Risk Score Implementation and Stratification for Managing Blood Pressure | Arterial Occlusive Diseases, Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, arteriosclerosis disorder, atherosclerosis, atherosclerotic cardiovascular disease, cardiovascular disorder, disease susceptibility, hypertensive disorder, inherited disease susceptibility, vascular disorder | Recruiting | Not applicable | 2026-10-09 | NCT06962488 | |
| The Genomic Medicine at VA Study | Arrhythmias, Cardiac, Arterial Occlusive Diseases, Digestive System Diseases, Digestive System Neoplasms, Disease Attributes, Genetic Risk Score, Genital Diseases, Male Urogenital Diseases, Neoplasms by Site, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, Urogenital Diseases, Urogenital Neoplasms, arteriosclerosis disorder, atrial fibrillation, breast cancer, breast disorder, breast neoplasm, cardiovascular disorder, colonic disorder, colorectal cancer, colorectal neoplasm, coronary artery disorder, diabetes mellitus, digestive system disorder, digestive system neoplasm, disease susceptibility, endocrine system disorder, glucose metabolism disease, heart disorder, inherited disease susceptibility, intestinal disorder, male reproductive organ cancer, male reproductive system disorder, metabolic disease, myocardial ischemia, neoplasm, prostate cancer, prostate disorder, rectal disorder, skin disorder, type 2 diabetes mellitus, vascular disorder | Active, not recruiting | Not applicable | 2026-10-02 | NCT04331535 | |
| Predicting Pre-dementia | Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, brain disorder, central nervous system disorder, cognitive disorder, dementia, disease susceptibility, inherited disease susceptibility, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Not stated | 2026-09-22 | NCT07516119 | |
| Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score | Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, disease susceptibility, inherited disease susceptibility | Recruiting | Phase 4 | 2026-09-01 | NCT07490067 | |
| Measuring Athlete's Risk of Cardiovascular Events 3 (MARC-3) | Arterial Occlusive Diseases, Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Plaque, Atherosclerotic, arteriosclerosis disorder, atherosclerosis, cardiovascular disorder, coronary artery disorder, disease susceptibility, heart disorder, inherited disease susceptibility, myocardial ischemia, vascular disorder | Enrolling by invitation | Not stated | 2026-08-13 | NCT07625488 | |
| Implementing Polygenic Risk Scores for Breast Cancer Prevention: a Feasibility Study | Disease Attributes, Genetic Risk Score, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, disease susceptibility, inherited disease susceptibility, neoplasm, skin disorder | Recruiting | Not applicable | 2026-08-03 | NCT06922708 | |
| Non-Invasive Diagnostic Panel for MASLD in Children With Obesity | Body Weight, Digestive System Diseases, Disease Attributes, Genetic Risk Score, Insulin Resistance, Nutritional and Metabolic Diseases, Overweight, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Pediatric Obesity, Signs and Symptoms, disease susceptibility, fatty liver disease, glucose metabolism disease, hyperinsulinism, inherited disease susceptibility, liver disorder, metabolic disease, metabolic dysfunction-associated steatotic liver disease, nutritional disorder, obesity disorder, overnutrition | Not yet recruiting | Not stated | 2026-07-30 | NCT07731360 | |
| Early Prediction of Outcomes Following Optic Neuritis: Development and Acceptability of a Prognostic Tool | CNS demyelinating autoimmune disease, Disease Attributes, Genetic Risk Score, Hemic and Lymphatic Diseases, Hypersensitivity, Delayed, Pathologic Processes, Pathological Conditions, Signs and Symptoms, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, cranial nerve neuropathy, demyelinating disease, disease susceptibility, eye disorder, immune system disorder, inherited disease susceptibility, lymphatic system disorder, lymphoproliferative syndrome, multiple sclerosis, nervous system disorder, neuromyelitis optica, optic nerve disorder, optic neuritis, sarcoidosis | Not yet recruiting | Not stated | 2026-07-15 | NCT07704294 | |
| Precision Obesity Medicine: Genetic Prediction of Response to GLP-1/GIP Agonists. | Body Weight, Disease Attributes, Genetic Risk Score, Nutritional and Metabolic Diseases, Overweight, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, disease susceptibility, inherited disease susceptibility, nutritional disorder, obesity disorder, overnutrition | Recruiting | Not stated | 2026-07-10 | NCT07653412 | |
| Polygenic Risk Score for Optimizing Primary Prevention in Intermediate-Risk Populations | Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, cardiovascular disorder, disease susceptibility, inherited disease susceptibility | Active, not recruiting | Not applicable | 2026-06-30 | NCT07039123 | |
| Exocrine-Endocrine Pancreatic Crosstalk: Precision Pathways to Reframe Diabetes Pathophysiology | Chronic Disease, Digestive System Diseases, Digestive System Neoplasms, Disease Attributes, Genetic Risk Score, Insulin Resistance, Neoplasms by Site, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, chronic pancreatitis, diabetes mellitus, disease susceptibility, endocrine system disorder, glucose metabolism disease, hyperinsulinism, inherited disease susceptibility, malignant endocrine neoplasm, metabolic disease, neoplasm, pancreas disorder, pancreatic neoplasm, pancreatitis, prediabetes syndrome, type 2 diabetes mellitus | Not yet recruiting | Not stated | 2026-06-26 | NCT07670871 | |
| Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Change in Cardiovascular Health | Arterial Occlusive Diseases, Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, arteriosclerosis disorder, atherosclerosis, cardiovascular disorder, coronary artery disorder, disease susceptibility, heart disorder, inherited disease susceptibility, myocardial ischemia, vascular disorder | Active, not recruiting | Not applicable | 2026-06-12 | NCT05819814 | |
| Prediction of Atrial Fibrillation Using Polygenic Risk Score | Arrhythmias, Cardiac, Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, atrial fibrillation, cardiovascular disorder, disease susceptibility, heart disorder, inherited disease susceptibility | Recruiting | Not applicable | 2026-06-11 | NCT07641582 | |
| Genetic Risk Score of Type 1 Diabetes Mellitus for Progression to Insulin in Diabetic Patients Lack of Predictive Value: a Multicenter Nested Case-control Study | Disease Attributes, Genetic Risk Score, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, autoimmune disease, diabetes mellitus, disease susceptibility, endocrine system disorder, glucose metabolism disease, immune system disorder, inherited disease susceptibility, metabolic disease, type 1 diabetes mellitus | Recruiting | Not stated | 2026-06-02 | NCT07621445 | |
| Polygenic Risk Driven Pragmatic Statin Trial for Heart Disease Prevention | Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, disease susceptibility, inherited disease susceptibility | Active, not recruiting | Phase 4 | 2026-05-13 | NCT06820086 | |
| Rapid Engagement for Solutions to Population and Outcomes Through Networked Dialogue for Coronary Heart Disease | Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, cardiovascular disorder, coronary artery disorder, disease susceptibility, heart disorder, inherited disease susceptibility, myocardial ischemia, vascular disorder | Not yet recruiting | Not stated | 2026-05-04 | NCT07260552 | |
| Diagnostic Value of Exome/ Genome Sequencing, Conventional Methods in Rare Diseases and Familial Tumor Syndromes | Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Rare Diseases, disease susceptibility, inherited disease susceptibility | Recruiting | Not stated | 2026-05-04 | NCT04731857 | |
| Pharmacogenomic Informed Statin Prescribing | Arterial Occlusive Diseases, Disease Attributes, Dyslipidemias, Genetic Risk Score, Hypercholesterolemia, Lipid Metabolism Disorders, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, arteriosclerosis disorder, atherosclerosis, cardiovascular disorder, disease susceptibility, hyperlipidemia, inherited disease susceptibility, metabolic disease, vascular disorder | Recruiting | Not applicable | 2026-04-13 | NCT06568601 | |
| Study of a Polygenic Risk Score to Predict the Risk of Pancreatic Ductal Adenocarcinoma | Digestive System Diseases, Digestive System Neoplasms, Disease Attributes, Genetic Risk Score, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, disease susceptibility, endocrine system disorder, inherited disease susceptibility, malignant endocrine neoplasm, neoplasm, pancreas disorder, pancreatic neoplasm | Not yet recruiting | Not applicable | 2026-04-08 | NCT07516392 | |
| Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health | Arterial Occlusive Diseases, Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, arteriosclerosis disorder, atherosclerosis, cardiovascular disorder, coronary artery disorder, disease susceptibility, heart disorder, inherited disease susceptibility, myocardial ischemia, vascular disorder | Recruiting | Not applicable | 2026-03-23 | NCT07087431 | |
| Genetic Architecture of Natriuretic Peptides and Blood Pressure Response | Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, cardiovascular disorder, disease susceptibility, hypertensive disorder, inherited disease susceptibility, vascular disorder | Not yet recruiting | Not applicable | 2026-03-10 | NCT07118592 | |
| Evaluation of Polygenic Risk Score for Epithelial OVarian cancEr Risk Prediction: the PROVE Study | Adnexal Diseases, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genetic Risk Score, Genital Diseases, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, Urogenital Neoplasms, disease susceptibility, endocrine system disorder, female reproductive system disorder, female reproductive system neoplasm, gonadal disorder, inherited disease susceptibility, malignant endocrine neoplasm, neoplasm, ovarian cancer, ovarian disorder | Recruiting | Not stated | 2026-03-03 | NCT06935344 | |
| General Population Level Estimation for Type 1 Diabetes Risk in Children During Routine Care Delivery | Acid-Base Imbalance, Diabetes Complications, Digestive System Diseases, Disease Attributes, Genetic Risk Score, Ketosis, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, acidosis disorder, autoimmune disease, celiac disease, diabetes mellitus, diabetic ketoacidosis, digestive system disorder, disease susceptibility, endocrine system disorder, glucose metabolism disease, immune system disorder, inherited disease susceptibility, intestinal disorder, malabsorption syndrome, metabolic disease, type 1 diabetes mellitus | Recruiting | Not stated | 2026-03-02 | NCT04477928 | |
| Personalised HeartCare: Poligenic Risk Scores Disclosure for Cardiovascular Prevention | Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, cardiovascular disorder, disease susceptibility, inherited disease susceptibility | Recruiting | Not applicable | 2026-02-20 | NCT06888466 | |
| The i4i PRODICT® Study: Evaluation of the i4i PRODICT® Test in Different Ethnic Groups (The i4i PRODICT® Study). | Disease Attributes, Genetic Risk Score, Genital Diseases, Male Urogenital Diseases, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, Urogenital Neoplasms, disease susceptibility, inherited disease susceptibility, male reproductive organ cancer, male reproductive system disorder, neoplasm, prostate cancer, prostate disorder | Recruiting | Not stated | 2026-02-04 | NCT06636526 |