Muscle Hypertonia
Muscle Hypertonia
Explore linked clinical trials. Standard reference: MESH:M0014236130 results · Page 1 of 6
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| At Home Use of Stimulation Suits for Managing MS Symptoms | Ataxia, Motor, CNS demyelinating autoimmune disease, Dyskinesias, Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, atactic disorder, non-human animal, autoimmune disease, autoimmune disorder of the nervous system, brain disorder, central nervous system disorder, cerebellar ataxia, cerebellar disorder, demyelinating disease, immune system disorder, multiple sclerosis, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder | Recruiting | Not applicable | 2026-10-08 | NCT07202195 | |
| Spinal Mobility, Rigidity, and Kinesiophobia in PD and TMD | Craniomandibular Disorders, Jaw Diseases, Mandibular Diseases, Muscle Hypertonia, Muscle Rigidity, Neurologic Manifestations, Neuromuscular Manifestations, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Stomatognathic Diseases, arthropathy, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, synucleinopathy, temporomandibular joint disorder | Recruiting | Not stated | 2026-10-05 | NCT07850674 | |
| Effect of Neural Constraints on Movement in Stroke | Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, stroke disorder, vascular disorder | Recruiting | Early phase 1 | 2026-10-05 | NCT06666673 | |
| Leg Stretching Using an Exoskeleton on Demand for People With Spasticity | Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, central nervous system disorder, injury, movement disorder, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, nervous system injury, spinal cord disorder, spinal cord injury | Recruiting | Not applicable | 2026-10-02 | NCT05926596 | |
| A Pilot Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368, a FAAH/MAGL Inhibitor, in Participants With Post-Stroke Spasticity (The STIPS Study) | Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, stroke disorder, vascular disorder | Recruiting | Phase 2 | 2026-10-01 | NCT07704840 | |
| A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity | CNS demyelinating autoimmune disease, Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autoimmune disease, autoimmune disorder of the nervous system, demyelinating disease, immune system disorder, multiple sclerosis, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder | Recruiting | Phase 2 | 2026-10-01 | NCT06782490 | |
| rTMS Treatment of Spasticity in Children With Cerebral Palsy/ Hemiplegia Due to ABI - a RCT | Brain Damage, Chronic, Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, cerebral palsy, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder | Recruiting | Not applicable | 2026-09-28 | NCT06128746 | |
| Spinal Cord Stimulation for Poststroke Spasticity | Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, stroke disorder, vascular disorder | Recruiting | Not applicable | 2026-09-21 | NCT07744659 | |
| First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD) | Cognition Disorders, Cognitive Dysfunction, Dyskinesias, Muscle Hypertonia, Muscle Rigidity, Neurologic Manifestations, Neuromuscular Manifestations, Parasomnias, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Tremor, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, mood disorder, movement disorder, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, primary dysautonomia, psychiatric disorder, sleep-wake disorder, synucleinopathy | Recruiting | Phase 1 | 2026-09-21 | NCT07216066 | |
| Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease | Atrophy, Muscle Cramp, Muscle Hypertonia, Muscle Spasticity, Muscle Weakness, Musculoskeletal Pain, Myalgia, Neurologic Manifestations, Neuromuscular Manifestations, Pain, Pathologic Processes, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, muscle tissue disorder, muscular atrophy, musculoskeletal system disorder, nervous system disorder, neuromuscular disease | Active, not recruiting | Not stated | 2026-09-21 | NCT03660969 | |
| Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning | Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, central nervous system disorder, injury, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, nervous system injury, palsy, spinal cord disorder, spinal cord injury | Recruiting | Not applicable | 2026-09-15 | NCT05094362 | |
| Outcomes of Neurosurgical Tone Management | Brain Damage, Chronic, Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, cerebral palsy, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder | Recruiting | Not stated | 2026-09-14 | NCT07817745 | |
| The Effect of Whole-Body Vibration Therapy Following Botulinum Toxin A Injection on Spasticity and Balance in Stroke Patients | Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, stroke disorder, vascular disorder | Recruiting | Not applicable | 2026-09-03 | NCT07286435 | |
| The Use of Photobiomodulation in the Treatment of Spasticity After Stroke. | Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, stroke disorder, vascular disorder | Recruiting | Phase 1 / Phase 2 | 2026-09-01 | NCT07784231 | |
| Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spasticity | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, cone-rod dystrophy, eye disorder, hereditary disease, inherited retinal dystrophy, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, retinal degeneration, retinal disorder | Active, not recruiting | Not applicable | 2026-09-01 | NCT05429736 | |
| Robot Aided Rehabilitation - Multi-joint Evaluations | Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, hemiplegia, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, palsy, stroke disorder, vascular disorder | Recruiting | Not stated | 2026-09-01 | NCT02359812 | |
| Robot Aided Rehabilitation - Intervention | Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, stroke disorder, vascular disorder | Recruiting | Not applicable | 2026-09-01 | NCT02359253 | |
| Electrical Neuromodulation for Modifying Spinal Network Involved in Spasticity | Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Spasm, central nervous system disorder, injury, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, nervous system injury, spinal cord disorder, spinal cord injury | Active, not recruiting | Not applicable | 2026-08-28 | NCT07792616 | |
| Intermittent Theta-Burst Stimulation for Lower-Limb Spasticity and Pain in Multiple Sclerosis | CNS demyelinating autoimmune disease, Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pain, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autoimmune disease, autoimmune disorder of the nervous system, demyelinating disease, immune system disorder, multiple sclerosis, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neuralgia, neuromuscular disease, peripheral nervous system disorder | Not yet recruiting | Not applicable | 2026-08-26 | NCT07786506 | |
| Task Practice and Spinal Cord Stimulation | Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Spastic, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder | Active, not recruiting | Not applicable | 2026-08-26 | NCT06494020 | |
| Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain | Cervical Spondylosis, Chronic Pain, Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pain, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, arthritic joint disease, arthropathy, autonomic nervous system disorder, bone disorder, chronic pain syndrome, complex regional pain syndrome, complex regional pain syndrome type 2, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neuralgia, neuromuscular disease, osteoarthritis, osteoarthritis, hip, osteoarthritis, knee, peripheral nervous system disorder, rheumatic disorder, spondylosis, vertebral column disorder | Recruiting | Not stated | 2026-08-21 | NCT07639060 | |
| Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia | Abnormalities, Multiple, Airway Obstruction, Apnea, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Down syndrome, Dyssomnias, Muscle Hypertonia, Nasal Obstruction, Neurobehavioral Manifestations, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Respiration Disorders, Signs and Symptoms, Signs and Symptoms, Respiratory, Sleep Disorders, Intrinsic, chromosomal disorder, hereditary disease, intellectual disability, nasal disorder, nervous system disorder, obstructive sleep apnea syndrome, otorhinolaryngologic disease, psychiatric disorder, respiratory failure, respiratory system disorder, sleep apnea syndrome, sleep-wake disorder | Recruiting | Not applicable | 2026-08-19 | NCT05527652 | |
| Efficacy of Focused Shock Wave Therapy Before and After Botulinum Toxin Injection in Patients With Post-Stroke Spastic Equinus/Equinovarus Foot: A Randomized Clinical Trial | Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, stroke disorder, vascular disorder | Active, not recruiting | Not applicable | 2026-08-11 | NCT07758322 | |
| Dorsal Root Electrical Stimulation in Children With Cerebral Palsy | Brain Damage, Chronic, Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, cerebral palsy, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder | Recruiting | Not applicable | 2026-08-11 | NCT07715006 | |
| A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity. | Brain Injuries, Traumatic, Craniocerebral Trauma, Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, brain injury, central nervous system disorder, injury, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, nervous system injury | Recruiting | Phase 1 / Phase 2 | 2026-07-28 | NCT04752774 |