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Lethargy

Lethargy

Explore linked clinical trials. Standard reference: MESH:M0019969
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Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
The Volunteering-in-Place Program for Apathetic Assisted Living Residents With ADRDLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, psychiatric disorderRecruitingNot applicable2026-10-05NCT06735950
Motivational Intervention for Patients With SchizophreniaLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Psychotic Disorders, Schizophrenia Spectrum and Other Psychotic Disorders, Signs and Symptoms, nervous system disorder, psychiatric disorder, schizophreniaNot yet recruitingNot applicable2026-10-01NCT07853079
A Virtual Life Story Club Intervention to Improve Loneliness and Apathy in Community-Dwelling Older AdultsLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, nervous system disorderRecruitingNot applicable2026-09-25NCT06919094
Safety and Tolerability of IRL757 in Participants With Parkinson's Disease and ApathyLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, synucleinopathyRecruitingPhase 1 / Phase 22026-09-03NCT07461220
Accelerated rTMS for Apathy in Parkinson's DiseaseLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, synucleinopathyRecruitingNot applicable2026-08-27NCT07399496
Chronic Anergic Depression IDentification - Magnetic Resonance Imaging Exploration in the Elderly of Traits Related to OnsetLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, nervous system disorderRecruitingNot applicable2026-08-21NCT06663891
Multidimensional Apathy in Psychiatric Pathologies.Lethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, nervous system disorderRecruitingNot applicable2026-08-19NCT04757220
Study of the Effects of Atomoxetine on MotivationLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, nervous system disorderNot yet recruitingPhase 42026-08-18NCT07771595
Accelerated rTMS vs. Sham for Stroke ApathyLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, depressive disorder, ischemic disease, nervous system disorder, stroke disorder, vascular disorderRecruitingPhase 1 / Phase 22026-07-08NCT07113067
Apathy in Parkinson Disease TMS StudyLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, synucleinopathyRecruitingNot applicable2026-07-08NCT06087926
In Vivo Involvement of the Cholinergic and Dopaminergic Systems in the Pathophysiology of Apathy.Lethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, nervous system disorder, stroke disorder, vascular disorderRecruitingPhase 32026-06-10NCT03998852
SENS'REM - SENSoriality and Multi-Sensory Emotional Reminiscences: a Pilot StudyLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, psychiatric disorderNot yet recruitingNot applicable2026-05-26NCT07468305
Robotic Technologies for APATHy in Dementia: a Randomised Controlled Trial (RAPHAel)Lethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, psychiatric disorderRecruitingNot applicable2026-05-05NCT07404410
rTMS for Apathy Clinical TrialAlzheimer disease, Cognition Disorders, Cognitive Dysfunction, Lethargy, Mild Cognitive Impairment, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathyRecruitingNot applicable2026-04-13NCT05561205
Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant DepressionAnhedonia, Depressive Disorder, Treatment-Resistant, Lethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, anxiety, anxiety disorder, depressive disorder, mood disorder, nervous system disorder, psychiatric disorderRecruitingNot stated2026-03-31NCT07146503
Targeting Apathy With Music in Parkinson's DiseaseLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, synucleinopathyRecruitingNot applicable2026-03-23NCT05505019
Evaluation of Three Tests to Assess Social Cognition in Huntington DiseaseCognition Disorders, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyskinesias, Huntington disease, Lethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, choreatic disease, cognitive disorder, dementia, depressive disorder, hereditary disease, inherited neurodegenerative disorder, movement disorder, nervous system disorder, neurodegenerative disease, psychiatric disorderRecruitingNot stated2026-03-11NCT07253038
Effects of Personalized Digital Reminiscence Therapy on Patients With Neurocognitive DisordersCognition Disorders, Cognitive Dysfunction, Lethargy, Mild Cognitive Impairment, Mild Neurocognitive Disorder, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, psychiatric disorderRecruitingNot stated2026-03-09NCT07237009
Neural Bases of MotivationLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, nervous system disorderRecruitingNot applicable2026-01-22NCT07251816
A Randomized Double-Blind Active-Controlled Crossover Trial of Respiratory-Gated Versus Non-Gated Transcutaneous Auricular Vagus Nerve Stimulation for the Treatment of Motor and Non-Motor Symptoms in Parkinson's DiseaseLethargy, Motor Disorders, Neurobehavioral Manifestations, Neurologic Manifestations, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, mood disorder, movement disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, psychiatric disorder, sleep-wake disorder, synucleinopathyEnrolling by invitationNot applicable2025-12-19NCT06642454
Combined Brain Stimulation and Methylphenidate Treatment for Apathy in DementiaAlzheimer disease, Lethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathyRecruitingPhase 22025-12-12NCT07279740
Effects of t-DCS and Cognitive Training on Apathy in Elderly With Minor Neurocognitive ImpairmentLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, cognitive disorder, nervous system disorder, psychiatric disorderActive, not recruitingNot applicable2025-11-26NCT05232877
Respiratory-gated Transcutaneous Auricular Vagus Nerve Stimulation for Improving Apathy in Parkinson's DiseaseLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, synucleinopathyRecruitingNot applicable2025-11-19NCT07118956
Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital TherapeuticsLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, depressive disorder, major depressive disorder, mood disorder, nervous system disorder, psychiatric disorderRecruitingNot applicable2025-10-22NCT05877885
VC/VS for Apathy in PDLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, synucleinopathyNot yet recruitingNot applicable2025-05-31NCT06991335