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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including MesotheliomaAdnexal Diseases, Digestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, Urogenital Diseases, Urogenital Neoplasms, adenoma, colonic disorder, colonic neoplasm, colorectal neoplasm, digestive system disorder, digestive system neoplasm, endocrine system disorder, epithelial neoplasm, female reproductive system disorder, female reproductive system neoplasm, gastric neoplasm, gonadal disorder, intestinal disorder, lung disorder, lung neoplasm, lymphatic system disorder, malignant endocrine neoplasm, mesothelial neoplasm, mesothelioma, mixed neoplasm, neoplasm, ovarian cancer, ovarian disorder, pancreas disorder, pancreatic neoplasm, respiratory system disorder, respiratory tract neoplasm, stomach disorder, thymomaRecruitingPhase 12026-10-06NCT06885697
A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based ChemotherapyHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, autosomal dominant Parkinson disease 4, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaActive, not recruitingPhase 22026-10-02NCT03076554
Tissue Procurement and Natural History Study of Patients With Malignant MesotheliomaAdnexal Diseases, Biliary Tract Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, Urogenital Diseases, Urogenital Neoplasms, adenoma, biliary tract disorder, digestive system disorder, digestive system neoplasm, endocrine system disorder, epithelial neoplasm, female reproductive system disorder, female reproductive system neoplasm, gastric neoplasm, gonadal disorder, lung disorder, lung neoplasm, lymphatic system disorder, malignant endocrine neoplasm, mesothelial neoplasm, mesothelioma, mixed neoplasm, neoplasm, ovarian cancer, ovarian disorder, pancreas disorder, pancreatic neoplasm, respiratory system disorder, respiratory tract neoplasm, stomach disorder, thymomaRecruitingNot stated2026-10-02NCT01950572
Incidence and Predictors of Early Clinical Relapse Within Six Months After Thymectomy in Patients With Myasthenia GravisDisease Attributes, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Paraneoplastic Syndromes, Nervous System, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, Thoracic Neoplasms, Thymus Neoplasms, autoimmune disease, autoimmune disorder of the nervous system, immune system disorder, lymphatic system disorder, mixed neoplasm, myasthenia gravis, neoplasm, nervous system disorder, neurodegenerative disease, neuromuscular disease, neuromuscular junction disease, paraneoplastic syndrome, thymomaNot yet recruitingNot stated2026-10-01NCT07853378
An Investigational Scan (MRI) in Imaging Patients With Newly-Diagnosed or Recurrent ThymomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaActive, not recruitingNot applicable2026-09-18NCT03968315
HEARTS Trial for Thoracic CancersDigestive System Diseases, Digestive System Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, bronchial neoplasm, bronchogenic carcinoma, digestive system disorder, digestive system neoplasm, esophageal disorder, lung disorder, lung neoplasm, lymphatic system disorder, mixed neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasm, thymomaRecruitingPhase 22026-09-15NCT07132918
SP Thoracic IDE StudyHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Paraneoplastic Syndromes, Nervous System, Thoracic Neoplasms, Thymus Neoplasms, autoimmune disease, autoimmune disorder of the nervous system, immune system disorder, lymphatic system disorder, mixed neoplasm, myasthenia gravis, neoplasm, nervous system disorder, neurodegenerative disease, neuromuscular disease, neuromuscular junction disease, paraneoplastic syndrome, thymomaActive, not recruitingNot applicable2026-09-14NCT05150210
A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial TumorsHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaRecruitingPhase 22026-09-11NCT06248515
PT-112 in Subjects With Thymoma and Thymic CarcinomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, nervous system disorder, neuromuscular disease, peripheral nervous system disorder, thymic epithelial neoplasm, thymoma, thymus cancerRecruitingPhase 22026-08-28NCT05104736
Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic CarcinomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymic epithelial neoplasm, thymoma, thymus cancerActive, not recruitingPhase 22026-08-28NCT04417660
Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic CarcinomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaRecruitingPhase 22026-08-12NCT07324629
A Phase II, Investigator-Initiated Exploratory Study of Sacituzumab Tirumotecan for Previously Treated Unresectable Thymic CarcinomasHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaNot yet recruitingPhase 22026-08-06NCT07750353
Pembrolizumab and Sunitinib Malate in Treating Participants With Refractory Metastatic or Unresectable Thymic CancerHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaActive, not recruitingPhase 22026-08-06NCT03463460
Chemotherapy Plus Cetuximab Followed by Surgical Resection in Patients With Locally Advanced or Recurrent Thymoma or Thymic CarcinomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaActive, not recruitingPhase 22026-07-29NCT01025089
Hypofractionated Adjuvant Radiotherapy for Thymic Epithelial TumorsHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymic epithelial neoplasm, thymomaNot yet recruitingNot applicable2026-07-16NCT07693855
Pembrolizumab in Treating Participants With Unresectable Thymoma or Thymic CancerHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaRecruitingPhase 12026-07-16NCT03295227
Prospective Data Collection Initiative on Thoracic MalignanciesHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, adenocarcinoma, adenoma, bronchial neoplasm, bronchogenic carcinoma, carcinoma, epithelial neoplasm, lung cancer, lung disorder, lung large cell carcinoma, lung neoplasm, lymphatic system disorder, mesothelial neoplasm, mesothelioma, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasm, squamous cell carcinoma, squamous cell neoplasm, thoracic cancer, thymus cancerRecruitingNot stated2026-07-07NCT06996249
Integrated Cancer Repository for Cancer ResearchAbdominal Neoplasms, Adenomatous Polyps, Adnexal Diseases, Anal Cancer, Biliary Tract Neoplasms, Blood Protein Disorders, Colorectal Neoplasms, Hereditary Nonpolyposis, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cronkhite-Canada syndrome, DNA repair disease, Digestive System Diseases, Digestive System Neoplasms, Duodenal Cancer, Esophageal Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Head and Neck Neoplasms, Hemic and Lymphatic Diseases, Liver Neoplasms, Lynch syndrome, Male Urogenital Diseases, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neoplasms, Unknown Primary, Neoplastic Processes, Nose Neoplasms, Nutritional and Metabolic Diseases, Otorhinolaryngologic Neoplasms, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Peritoneal Diseases, Peritoneal Surface Malignancy, Pharyngeal Diseases, Skin and Connective Tissue Diseases, Stomatognathic Diseases, Thoracic Neoplasms, Thymus Neoplasms, Thyroid Nodule, Unknown Primary Tumors, Urogenital Diseases, Urogenital Neoplasms, adenoma, anus disorder, anus neoplasm, benign urinary system neoplasm, bile duct cancer, bile duct disorder, bile duct neoplasm, biliary tract disorder, breast cancer, breast disorder, breast neoplasm, cardiovascular disorder, central nervous system cancer, classic familial adenomatous polyposis, colonic disorder, colonic neoplasm, colorectal neoplasm, connective tissue neoplasm, digestive system disorder, digestive system neoplasm, duodenal disorder, duodenum cancer, endocrine system disorder, endometrium neoplasm, epithelial neoplasm, esophageal cancer, esophageal disorder, female reproductive system disorder, female reproductive system neoplasm, gallbladder disorder, gallbladder neoplasm, gastric cancer, gastric neoplasm, gastrointestinal stromal tumor, gonadal disorder, hematologic disorder, hemorrhagic disease, hereditary disease, hereditary neoplastic syndrome, hypopharynx cancer, immune system disorder, immunoproliferative disorder, intestinal disorder, kidney cancer, kidney disorder, laryngeal disorder, laryngeal neoplasm, larynx cancer, leukemia, lip cancer, lip disorder, liver cancer, liver disorder, lung cancer, lung disorder, lung neoplasm, lymphatic system disorder, lymphoproliferative syndrome, male reproductive organ cancer, male reproductive system disorder, malignant colon neoplasm, malignant endocrine neoplasm, malignant pancreatic neoplasm, malignant tumor of nasopharynx, melanocytic neoplasm, melanoma, mesothelial neoplasm, mesothelioma, metabolic disease, monoclonal gammopathy, mouth disorder, nasal cavity cancer, nasal disorder, nasopharyngeal disorder, nasopharyngeal neoplasm, neoplasm, nervous system disorder, neuroendocrine neoplasm, oral cavity cancer, otorhinolaryngologic disease, ovarian cancer, ovarian disorder, pancreas disorder, pancreatic neoplasm, paranasal sinus cancer, paranasal sinus disorder, paranasal sinus neoplasm, penile cancer, penile disorder, penile neoplasm, peritoneal neoplasm, plasma cell neoplasm, primitive neuroectodermal tumor, prostate cancer, prostate disorder, rectal cancer, rectal disorder, rectal neoplasm, respiratory system disorder, respiratory tract neoplasm, salivary gland cancer, salivary gland disorder, sarcoma, skin disorder, skin neoplasm, small intestine cancer, stomach disorder, testicular cancer, testicular disorder, thymus cancer, thyroid gland disorder, thyroid tumor, ureter cancer, ureteral disorder, urethra neoplasm, urethral disorder, urinary bladder cancer, urinary bladder disorder, urinary bladder neoplasm, urinary system disorder, uterine disorder, vaginal cancer, vaginal disorder, vascular disorder, vascular hemostatic diseaseRecruitingNot stated2026-06-29NCT02012699
IMMUNORARE5: A National Platform of 5 Academic Phase II Trials Coordinated by Lyon University Hospital to Assess the Safety and the Efficacy of the IMMUNOtherapy With Domvanalimab + Zimberelimab Combination in Patients With Advanced RARE CancersFemale Urogenital Diseases and Pregnancy Complications, Gestational Trophoblastic Disease, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Pregnancy Complications, Neoplastic, Thoracic Neoplasms, Thymus Neoplasms, Urogenital Diseases, adenocarcinoma, carcinoid tumor, carcinoma, digestive system neuroendocrine neoplasm, epithelial neoplasm, gestational trophoblastic neoplasm, lymphatic system disorder, mixed neoplasm, neoplasm, neuroendocrine neoplasm, peritoneal mesothelioma, pregnancy disorder, primitive neuroectodermal tumor, thymoma, thyroid gland undifferentiated (anaplastic) carcinoma, trophoblastic neoplasmActive, not recruitingPhase 22026-06-25NCT06790706
Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete ResectionHemic and Lymphatic Diseases, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, neoplasmActive, not recruitingNot applicable2026-06-16NCT06189183
Target-Selected CAR-NK Cells (CD30, CD5, or Mesothelin) for Relapsed/Refractory B2 Thymoma or Thymic CarcinomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymic epithelial neoplasm, thymomaRecruitingPhase 1 / Phase 22026-05-20NCT07598955
Nivolumab in Patients With Type B3 Thymoma and Thymic Carcinoma (NIVOTHYM)Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymoma, thymoma type B3Active, not recruitingPhase 22026-05-15NCT03134118
Efficacy and Safety of Radiotherapy Compared to Everolimus in Somatostatin Receptor Positive Neuroendocrine Tumors of the Lung and Thymus.Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Thoracic Neoplasms, Thymus Neoplasms, lung neuroendocrine neoplasm, lymphatic system disorder, neoplasm, neuroendocrine neoplasm, primitive neuroectodermal tumorRecruitingPhase 32026-05-12NCT05918302
Neoadjuvant Treatment For Locally Advanced Thymic CancerHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaRecruitingPhase 22026-05-08NCT06019468
Thymic Disease, Autoimmunity, and Neuromuscular Junction Integrity in Myasthenia GravisHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Paraneoplastic Syndromes, Nervous System, Thoracic Neoplasms, Thymus Neoplasms, autoimmune disease, autoimmune disorder of the nervous system, immune system disorder, lymphatic system disorder, mixed neoplasm, myasthenia gravis, neoplasm, nervous system disorder, neurodegenerative disease, neuromuscular disease, neuromuscular junction disease, paraneoplastic syndrome, thymomaNot yet recruitingNot stated2026-05-06NCT07571525