Hyperpigmentation
Hyperpigmentation
Explore linked clinical trials. Standard reference: MESH:M002654648 results · Page 1 of 2
Clinical trials
Swipe the table sideways for more columns.
| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Foam Sclerotherapy With or Without Transdermal Laser for Reticular Veins and Telangiectasias | Hyperpigmentation, Skin and Connective Tissue Diseases, cardiovascular disorder, skin disorder, skin pigmentation disorder, telangiectasis, vascular disorder | Recruiting | Phase 4 | 2026-10-05 | NCT07793630 | |
| Treatment and Prevention of Melasma Relapses by Using 1064nm 650 Microsecond Laser | Chloasma, Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Active, not recruiting | Not applicable | 2026-10-01 | NCT06644157 | |
| Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color | Hyperpigmentation, Hypertrophy, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Recruiting | Not applicable | 2026-10-01 | NCT05362929 | |
| Efficacy Evaluation of a Cosmetic Product for Facial Hyperpigmentation | Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Recruiting | Not applicable | 2026-09-16 | NCT07769268 | |
| The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics | Chronic Disease, Colorectal Neoplasms, Hereditary Nonpolyposis, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cronkhite-Canada syndrome, Cysts, DNA repair disease, Digestive System Diseases, Digestive System Neoplasms, Disease Attributes, Dyskinesias, Familial Atypical Multiple Mole-Melanoma, Hyperpigmentation, Lynch syndrome, Melanosis, Neoplasms by Histologic Type, Neoplasms by Site, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pancreatic Cyst, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Peutz-Jeghers syndrome, Primary Immunodeficiency Diseases, Skin and Connective Tissue Diseases, Spinocerebellar Ataxias, atactic disorder, non-human animal, ataxia telangiectasia, brain disorder, cardiovascular disorder, central nervous system disorder, cerebellar ataxia, cerebellar disorder, chronic pancreatitis, classic familial adenomatous polyposis, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, hereditary disease, hereditary neoplastic syndrome, immune system disorder, inborn error of immunity, intestinal disorder, lentigo, melanocytic neoplasm, melanocytic nevus, melanoma, cutaneous malignant, susceptibility to, 2, metabolic disease, neoplasm, nervous system disorder, neurocutaneous syndrome, pancreas disorder, pancreatic ductal adenocarcinoma, pancreatitis, skin disorder, skin pigmentation disorder, telangiectasis, vascular disorder | Active, not recruiting | Not stated | 2026-09-15 | NCT05692596 | |
| Topical Metformin Versus Triple Regimen for Epidermal Melasma | Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Not yet recruiting | Phase 2 | 2026-08-21 | NCT07779811 | |
| Efficacy and Safety Of Fractional Carbon Dioxide Laser Plus Topical Metformin In Treatment Of Acanthosis Nigricans | Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, acanthosis nigricans, skin disorder, skin pigmentation disorder | Not yet recruiting | Phase 1 | 2026-08-12 | NCT07760181 | |
| Oral Tranexamic Acid Plus Triple Combination vs Triple Combination Alone in Melasma | Chloasma, Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Not yet recruiting | Phase 4 | 2026-07-28 | NCT07732192 | |
| Microneedling-Assisted Metformin, Tranexamic Acid, and Modified Kligman's Formula for Melasma | Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Enrolling by invitation | Phase 4 | 2026-07-28 | NCT07696806 | |
| A Clinical Study to Evaluate the Efficacy in Improving Dark Spots After 8 Weeks of Use of Facial Sunscreens in Adult Participants | Chloasma, Hyperpigmentation, Melanosis, Post-Inflammatory Hyperpigmentation, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Recruiting | Not applicable | 2026-07-01 | NCT07679945 | |
| A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Treatment of Melasma | Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Active, not recruiting | Not applicable | 2026-07-01 | NCT01976286 | |
| Microfocused Ultrasound for Facial Pigmentary Diseases and Rosacea | Chloasma, Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, lichen planus pigmentosus, rosacea, skin disorder, skin pigmentation disorder | Active, not recruiting | Not applicable | 2026-06-30 | NCT07667972 | |
| Familial Investigations of Childhood Cancer Predisposition | Abnormalities, Multiple, Adenomatous Polyps, Adnexal Diseases, Bone Diseases, Developmental, Bone Marrow Failure Disorders, Cardiovascular Abnormalities, Carney complex, Ciliopathies, Colorectal Neoplasms, Hereditary Nonpolyposis, Congenital Abnormalities, Congenital Bone Marrow Failure Syndromes, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cowden disease, Craniofacial Abnormalities, Cronkhite-Canada syndrome, Cysts, DICER1-related tumor predisposition, DNA repair disease, Diamond-Blackfan anemia, Digestive System Diseases, Digestive System Neoplasms, Disease Attributes, Ear Diseases, Eye Diseases, Hereditary, Fanconi anemia, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, GATA2 deficiency with susceptibility to MDS/AML, Genital Diseases, Hemic and Lymphatic Diseases, Hodgkins lymphoma, Hyperpigmentation, Infant, Newborn, Diseases, Jaw Cysts, Jaw Diseases, Li-Fraumeni syndrome, Lynch syndrome, Malformations of Cortical Development, Group I, Melanosis, Musculoskeletal Abnormalities, Myosarcoma, NF2-related schwannomatosis, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Multiple Primary, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Noonan syndrome, Nutritional and Metabolic Diseases, Otorhinolaryngologic Neoplasms, PTEN hamartoma tumor syndrome, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Peutz-Jeghers syndrome, Rothmund-Thomson syndrome, Skin Abnormalities, Skin and Connective Tissue Diseases, Stomatognathic Diseases, Thoracic Neoplasms, Urogenital Diseases, Urogenital Neoplasms, X-linked disease, acoustic neuroma, acute leukemia, acute myeloid leukemia, adenocarcinoma, adenoma, adrenal cortex disorder, adrenal cortex neoplasm, adrenal gland cancer, adrenal gland disorder, anemia, angiomatosis, aplastic anemia, basal cell carcinoma, basal cell neoplasm, bone disorder, bone marrow disorder, breast disorder, breast neoplasm, carcinoma, cardiovascular disorder, central nervous system malformation, cerebral cortical dysplasia, choroid plexus carcinoma, classic familial adenomatous polyposis, colonic disorder, colorectal neoplasm, congenital heart disease, connective tissue disorder, connective tissue neoplasm, cranial nerve neoplasm, cranial nerve neuropathy, deafness-lymphedema-leukemia syndrome, digestive system disorder, digestive system neoplasm, disease susceptibility, dyskeratosis congenita, endocrine system disorder, epithelial neoplasm, eye disorder, familial rhabdoid tumor, female reproductive system disorder, female reproductive system neoplasm, gastrointestinal stromal tumor, gonadal disorder, hamartoma, heart cancer, heart disorder, hematologic disorder, hereditary Wilms tumor, hereditary breast ovarian cancer syndrome, hereditary disease, hereditary neoplastic syndrome, hereditary pheochromocytoma-paraganglioma, hereditary skin disorder, immune system disorder, immunoproliferative disorder, inherited aplastic anemia, inherited disease susceptibility, inherited neurodegenerative disorder, intestinal disorder, juvenile polyposis syndrome, lentigo, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, malignant endocrine neoplasm, malignant pancreatic neoplasm, melanocytic neoplasm, melanoma, metabolic disease, mismatch repair cancer syndrome, mismatch repair cancer syndrome 1, multiple endocrine neoplasia, multiple endocrine neoplasia type 1, multiple endocrine neoplasia type 2A, musculoskeletal system disorder, myelodysplastic syndrome, myomatous neoplasm, myxoma, neoplasm, nerve sheath neoplasm, nervous system disorder, neuroblastoma, neurocutaneous syndrome, neurodegenerative disease, neuroendocrine neoplasm, neuroepithelial neoplasm, neurofibroma, neurofibromatosis, neurofibromatosis type 1, neuroma, neuromuscular disease, nevoid basal cell carcinoma syndrome, non-Hodgkin lymphoma, ocular cancer, odontogenic cyst, otorhinolaryngologic disease, ovarian cancer, ovarian disorder, pancreas disorder, pancreatic neoplasm, paraganglioma, peripheral nervous system disorder, pheochromocytoma, pheochromocytoma-paraganglioma, primitive neuroectodermal tumor, pure red-cell aplasia, retinal cancer, retinal disorder, retinoblastoma, retrocochlear disease, rhabdomyosarcoma, sarcoma, schwannoma, skin disorder, skin neoplasm, skin pigmentation disorder, solitary bone cyst, tuberous sclerosis, vascular disorder, vestibulocochlear nerve disorder, von Hippel-Lindau disease | Recruiting | Not stated | 2026-06-17 | NCT03050268 | |
| Study on the Functional Impact of Cosmetics on Improving Self-Esteem and Quality of Life in Black Women | Hyperpigmentation, Post-Inflammatory Hyperpigmentation, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Recruiting | Not applicable | 2026-06-04 | NCT07618572 | |
| Comparative Efficacy of Intralesional Tranexamic Acid Versus Mandelic Acid Peel in the Treatment of Melasma | Chloasma, Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Not yet recruiting | Not applicable | 2026-05-28 | NCT07604844 | |
| Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser | Chloasma, Hyperpigmentation, Hypertrophy, Melanosis, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Active, not recruiting | Not applicable | 2026-05-19 | NCT07036302 | |
| Injectable Platelet-Rich Fibrin Versus Intradermal Tranexamic Acid for Melasma | Chloasma, Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Recruiting | Not applicable | 2026-04-22 | NCT07540702 | |
| Clinical Efficacy and Mechanisms of a Topical Azone-Tranexamic Acid-Aloe Polysaccharide Gel in the Treatment of Melasma | Chloasma, Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Not yet recruiting | Not applicable | 2026-04-14 | NCT07530016 | |
| Comparison Between Efficacy of Topical Tranexamic Acid Vs Topical Ethyl Ascorbic Acid In Treatment Of Melasma | Chloasma, Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Not yet recruiting | Phase 4 | 2026-04-13 | NCT07522788 | |
| Comparative Evaluation of Topical Metformin and Topical Tranexamic Acid in Melasma | Chloasma, Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Not yet recruiting | Not applicable | 2026-03-27 | NCT07495748 | |
| Comparative Evaluation of Topical 30% Metformin and Kligman's Regimen in Women With Melasma | Chloasma, Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Not yet recruiting | Not applicable | 2026-03-20 | NCT07485777 | |
| Evaluation of the Efficacy of Oral Tranexamic Acid and Glutathione-assisted Microneedling in Treatment of Melasma | Chloasma, Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Not yet recruiting | Phase 2 / Phase 3 | 2026-03-04 | NCT07448415 | |
| Evaluation of Efficacy and Tolerabilty of MelaB3 Serum in Combination of 35% Glycolic Acid Peeling Compared to 35% Glycolic Acid Peeling Alone in Various Hyperpigmentation Conditions | Chloasma, Hyperpigmentation, Melanosis, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Not yet recruiting | Not applicable | 2026-02-24 | NCT07429786 | |
| Pancreas Registry and High Risk Registry | Chronic Disease, Colorectal Neoplasms, Hereditary Nonpolyposis, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cronkhite-Canada syndrome, Cysts, DNA repair disease, Digestive System Diseases, Digestive System Neoplasms, Disease Attributes, Hyperpigmentation, Melanosis, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Nutritional and Metabolic Diseases, Pancreatic Cyst, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Peutz-Jeghers syndrome, Skin and Connective Tissue Diseases, chronic pancreatitis, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, endocrine system disorder, hereditary disease, hereditary neoplastic syndrome, intestinal disorder, lentigo, malignant endocrine neoplasm, malignant pancreatic neoplasm, melanocytic neoplasm, melanoma, metabolic disease, neoplasm, neuroendocrine neoplasm, pancreas disorder, pancreatic neoplasm, pancreatitis, primitive neuroectodermal tumor, skin disorder, skin neoplasm, skin pigmentation disorder, susceptibility to familial cutaneous melanoma | Recruiting | Not stated | 2026-02-11 | NCT02775461 | |
| Clinical Study to Assess Safety, Effectiveness and In-Use Tolerability of Saffron Extract Capsules for Improving Skin Health and Reducing Signs of Aging on Healthy Adult Male and Female Subjects. | Hyperpigmentation, Skin and Connective Tissue Diseases, skin disorder, skin pigmentation disorder | Not yet recruiting | Not applicable | 2026-01-07 | NCT07324759 |