Alzheimer Disease, Early Onset
Alzheimer Disease, Early Onset
Explore linked clinical trials. Standard reference: MESH:M033393131 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Study of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's Disease | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Phase 1 / Phase 2 | 2026-09-18 | NCT07221344 | |
| A Study of Donanemab, RG6289, or the Combination of Donanemab and RG6289 in Presenilin 1 (PSEN1) E280A Mutation Carriers for the Treatment of Autosomal-Dominant Alzheimer's Disease | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Phase 2 / Phase 3 | 2026-09-02 | NCT06996730 | |
| Cholinergic Deep Brain Stimulation for Alzheimer's Disease | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Enrolling by invitation | Not applicable | 2026-09-01 | NCT05882344 | |
| MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, posterior cortical atrophy, psychiatric disorder, tauopathy | Recruiting | Not applicable | 2026-08-20 | NCT04150198 | |
| Longitudinal Early-onset Alzheimer's Disease Study Protocol | Alzheimer Disease, Early Onset, Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Frontotemporal Lobar Degeneration, Mild Cognitive Impairment, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Pick disease, Plaque, Amyloid, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Active, not recruiting | Not stated | 2026-07-29 | NCT03507257 | |
| Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study | Alzheimer Disease, Early Onset, Alzheimer disease, amnestic disorder, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Not applicable | 2026-07-17 | NCT02740634 | |
| Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, logopenic progressive aphasia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Active, not recruiting | Not applicable | 2026-07-15 | NCT04122001 | |
| PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD) | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Active, not recruiting | Phase 1 | 2026-07-13 | NCT06750432 | |
| A Study to Assess THN391 in Subjects With Alzheimer's Disease | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Active, not recruiting | Phase 1 | 2026-07-08 | NCT06814730 | |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants With Early Alzheimer's Disease | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Phase 1 | 2026-07-01 | NCT07328451 | |
| MIMA Pilot Study: MIcrostructure of the Medial Temporal Lobe in Early Alzheimer's Disease | Alzheimer Disease, Early Onset, Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Not applicable | 2026-06-17 | NCT06099587 | |
| Neuronavigation-guided FUS-induced BBB Opening in Alzheimer's Disease Patients and Its Effects on Brain Amyloid and Tau | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Not yet recruiting | Phase 1 | 2026-05-13 | NCT06600880 | |
| Transcranial Magnetic Stimulation to Slow Down Cognitive Decline in Alzheimer's Disease | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Not applicable | 2026-05-12 | NCT07036328 | |
| Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Not applicable | 2026-05-06 | NCT05573490 | |
| A Study Testing Whether Low-Dose Radiation Could Help the Immune System and Possibly Improve Early-Onset Alzheimer's Disease. | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Not yet recruiting | Not applicable | 2026-05-04 | NCT07564700 | |
| Individualized Brain Stimulation to Improve Mobility in Alzheimer's Disease | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Active, not recruiting | Not applicable | 2026-04-27 | NCT04289402 | |
| A Multifocal tDCS-EEG Protocol for Improving Symptoms of Mild Cognitive Impairment and Early Dementia | Alzheimer Disease, Early Onset, Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Not applicable | 2026-04-22 | NCT06668610 | |
| Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Study | Alzheimer Disease, Early Onset, Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Mild Cognitive Impairment, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Active, not recruiting | Phase 2 | 2026-04-01 | NCT04685590 | |
| Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy | Alzheimer Disease, Early Onset, Alzheimer Disease, Late Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Not applicable | 2026-03-30 | NCT05655195 | |
| Theta-burst Stimulation on Cognitive Function in the Patients With Young-onset Alzheimer's Disease Dementia | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Enrolling by invitation | Not applicable | 2026-03-23 | NCT04042532 | |
| 48-hour Ambulatory EEG Monitoring in Early Onset Alzheimer's Disease | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Active, not recruiting | Not applicable | 2026-03-05 | NCT04002583 | |
| Donepezil Versus Non-drug Treatment in Alzheimer's Disease. | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Phase 3 | 2026-02-18 | NCT04661280 | |
| Network-based biOmarker Discovery of Neurodegenerative Diseases Using Multimodal Connectivity | Alzheimer Disease, Early Onset, Alzheimer disease, Parkinson disease, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, dementia, movement disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, psychiatric disorder, synucleinopathy, tauopathy | Recruiting | Not applicable | 2026-01-05 | NCT06080659 | |
| Effects of a Widely Used Vaccine Adjuvant in Subjects With Early Alzheimer's Disease Double-blind Study to Assess the Safety and Efficacy of AD04 in Patients With Early Alzheimer's Disease - ADVANCE | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Active, not recruiting | Phase 2 | 2025-08-06 | NCT07107074 | |
| Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease | Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Active, not recruiting | Phase 2 | 2025-07-24 | NCT06268886 |