Mitochondrial encephalopathy

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Trial	Conditions	Status	Phase	Updated	More info	NCT ID
An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)	Acid-Base Imbalance, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, Cerebral Small Vessel Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, MELAS syndrome, Mitochondrial encephalopathy, Nutritional and Metabolic Diseases, acidosis disorder, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, hereditary disease, inborn errors of metabolism, inborn mitochondrial metabolism disorder, inborn mitochondrial myopathy, lactic acidosis, metabolic disease, mitochondrial encephalomyopathy, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neuromuscular disease, vascular disorder	Active, not recruiting	Phase 2	2026-07-07		NCT06961344
Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome	Brain Diseases, Metabolic, Mitochondrial encephalopathy, Nutritional and Metabolic Diseases, brain disorder, central nervous system disorder, inborn mitochondrial metabolism disorder, inborn mitochondrial myopathy, metabolic disease, mitochondrial encephalomyopathy, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neuromuscular disease	Recruiting	Phase 2	2025-05-31		NCT04802707

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