Cirrhosis, Familial, with Pulmonary Hypertension
Cirrhosis, Familial, with Pulmonary Hypertension
Explore linked clinical trials. Standard reference: MESH:M056288029 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Perioperative Retlirafusp Alfa(Anti-PD-L1/TGF-β Bifunctional Fusion Protein) Plus Famitinib and GEMOX-Based Hepatic Arterial Infusion Chemotherapy for Locally Advanced Intrahepatic Cholangiocarcinoma: A Multicenter, Single-Arm, Exploratory Phase II Trial | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Recruiting | Phase 2 | 2026-10-09 | NCT07847710 | |
| PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma | Biliary Tract Neoplasms, Cirrhosis, Familial, with Pulmonary Hypertension, Digestive System Diseases, Digestive System Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, adenocarcinoma, adrenal cortex disorder, adrenal cortex neoplasm, adrenal gland cancer, adrenal gland disorder, bile duct cancer, bile duct disorder, bile duct neoplasm, biliary tract disorder, carcinoma, cholangiocarcinoma, colonic disorder, colorectal cancer, colorectal neoplasm, digestive system disorder, digestive system neoplasm, endocrine system disorder, epithelial neoplasm, intestinal disorder, intrahepatic bile duct cancer, malignant endocrine neoplasm, neoplasm, rectal disorder | Recruiting | Phase 2 | 2026-10-01 | NCT05286814 | |
| Additional Chemotherapy Administered Directly Into the Liver Using a Chemo Pump in Patients With Bile Duct Cancer Inside the Liver Treatable by Surgery | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, intrahepatic bile duct cancer, intrahepatic cholangiocarcinoma, neoplasm | Recruiting | Phase 2 | 2026-09-23 | NCT06888063 | |
| Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma (POELH-III) | Biliary Tract Neoplasms, Cirrhosis, Familial, with Pulmonary Hypertension, Digestive System Diseases, Digestive System Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, adenocarcinoma, bile duct disorder, bile duct neoplasm, biliary tract disorder, carcinoma, cholangiocarcinoma, common bile duct disorder, common bile duct neoplasm, epithelial neoplasm, hilar cholangiocarcinoma, neoplasm | Recruiting | Not stated | 2026-09-10 | NCT07161869 | |
| Phase 2 Study of Daraxonrasib in Recurrent KRAS-Mutant Biliary Tract Cancer | Biliary Tract Neoplasms, Cirrhosis, Familial, with Pulmonary Hypertension, Digestive System Diseases, Digestive System Neoplasms, Extrahepatic Cholangiocarcinoma, Liver Neoplasms, Neoplasm Metastasis, Neoplasms by Histologic Type, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, adenocarcinoma, biliary tract cancer, biliary tract disorder, carcinoma, carcinoma of the ampulla of vater, cholangiocarcinoma, digestive system disorder, digestive system neoplasm, epithelial neoplasm, gallbladder carcinoma, gallbladder disorder, gallbladder neoplasm, liver disorder, neoplasm | Not yet recruiting | Phase 2 | 2026-08-28 | NCT07793253 | |
| A Multicenter, Prospective, Randomized, Open-label Phase Ib/II Study of Celecoxib Plus Pembrolizumab and Gemcitabine/Cisplatin Versus Pembrolizumab and Gemcitabine/Cisplatin in Patients With CK5/6-High Unresectable Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Not yet recruiting | Phase 1 / Phase 2 | 2026-08-28 | NCT07632235 | |
| Pragmatic RCT of AI-Assisted Reading for Malignant Hepatic Lesions on CE-CT | Cirrhosis, Familial, with Pulmonary Hypertension, Cysts, Digestive System Diseases, Digestive System Neoplasms, Liver Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, focal nodular hyperplasia, hepatocellular carcinoma, liver disorder, neoplasm | Not yet recruiting | Not applicable | 2026-08-17 | NCT07768085 | |
| Protective Mechanisms of Phycocyanin in Partial Hepatectomy-Associated Liver Injury | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Recruiting | Not applicable | 2026-08-12 | NCT07760038 | |
| Intraarterial Therapies Plus Tislelizumab Plus Lenvatinib Versus Tislelizumab Plus Gemcitabine-Cisplatin in Unresectable Intrahepatic Cholangiocarcinoma | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Not yet recruiting | Phase 3 | 2026-07-14 | NCT07691515 | |
| AI Multimodal Model for Liver Cancer Diagnosis and Prognosis | Cirrhosis, Familial, with Pulmonary Hypertension, Digestive System Diseases, Digestive System Neoplasms, Liver Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, hepatocellular carcinoma, liver cancer, liver disorder, neoplasm | Active, not recruiting | Not stated | 2026-07-01 | NCT07658586 | |
| A Trial of Apatinib and Adebrelimab in Combination With Chemotherapy in Patients With Unresectable ICC | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Recruiting | Phase 2 | 2026-06-17 | NCT06925516 | |
| Efficacy and Safety of HAIC Combined With Lenvatinib and PD-1 Inhibitors for Advanced Intrahepatic Cholangiocarcinoma | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Active, not recruiting | Phase 2 | 2026-06-15 | NCT07646717 | |
| Adjuvant Therapy for High-Risk Intrahepatic Cholangiocarcinoma: A Real-World Study | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Recruiting | Not stated | 2026-06-10 | NCT07640048 | |
| Study Assessing PET Imaging With Zirconium-labelled Girentuximab in Patients With HCC, BTC or NEN | Cirrhosis, Familial, with Pulmonary Hypertension, Digestive System Diseases, Digestive System Neoplasms, Liver Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, hepatocellular carcinoma, liver disorder, neoplasm, neuroendocrine neoplasm, primitive neuroectodermal tumor | Recruiting | Not applicable | 2026-05-13 | NCT06735560 | |
| A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Active, not recruiting | Phase 1 / Phase 2 | 2026-04-17 | NCT06777316 | |
| Hepatic Arterial Infusion Chemotherapy (HAIC) Combined With Durvalumab and Lenvatinib in Patients With Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma: a Phase 2 Study(HAIC-quad Trial) | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Recruiting | Phase 2 | 2026-03-09 | NCT06859684 | |
| FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Not yet recruiting | Phase 2 | 2026-01-20 | NCT07353827 | |
| Prospective Evaluation of 68Ga-FAPI PET in Biliary Cancers | Biliary Tract Neoplasms, Cirrhosis, Familial, with Pulmonary Hypertension, Digestive System Diseases, Digestive System Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, adenocarcinoma, biliary tract disorder, carcinoma, cholangiocarcinoma, epithelial neoplasm, gallbladder disorder, gallbladder neoplasm, neoplasm | Recruiting | Not stated | 2026-01-13 | NCT07337850 | |
| Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or Mutations | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Not yet recruiting | Phase 3 | 2026-01-09 | NCT07328919 | |
| A Randomized Trial of Surgical Decision-Making Guided by TDTP-RECIST | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Not yet recruiting | Not applicable | 2025-10-06 | NCT07208526 | |
| A Cell-free DNA Methylation Blood-Based Test for Biliary Tract Cancers Screening | Biliary Tract Neoplasms, Cirrhosis, Familial, with Pulmonary Hypertension, Digestive System Diseases, Digestive System Neoplasms, Extrahepatic Cholangiocarcinoma, Neoplasms by Histologic Type, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, adenocarcinoma, biliary tract disorder, carcinoma, cholangiocarcinoma, disease, epithelial neoplasm, gallbladder disorder, gallbladder neoplasm, hilar cholangiocarcinoma, neoplasm | Recruiting | Not stated | 2025-09-16 | NCT07176962 | |
| PErioperative CISGEM + Rilvegostomig in High-Risk Resectable Intra Hepatic CholangioCarcinoma | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Not yet recruiting | Phase 2 | 2025-08-17 | NCT07128290 | |
| Cryoablation Combined With Lenvatinib Plus QL1706 (Iparomlimab/Tuvonralimab) in Patients With Advanced Intrahepatic Cholangiocarcinoma | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Recruiting | Phase 2 | 2025-08-12 | NCT07070700 | |
| A Prospective Phase II Study of Postoperative Concurrent Chemoradiotherapy in Patients With Intrahepatic Cholangiocarcinoma | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Recruiting | Phase 2 | 2025-07-14 | NCT07063888 | |
| Second-line Regimen Combined With Radiotherapy Versus Without Radiotherapy in Patients With Locally Advanced/Oligometastatic ICC After Failure of First-line Treatment：an Open-label, Randomized, Controlled Phase II Clinical Study | Cirrhosis, Familial, with Pulmonary Hypertension, Neoplasms by Histologic Type, adenocarcinoma, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Not yet recruiting | Phase 2 | 2025-04-27 | NCT06946849 |