Squamous Intraepithelial Lesions
Squamous Intraepithelial Lesions
Explore linked clinical trials. Standard reference: MESH:M058911926 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Papilozumib Vaginal Gel for Exocervical Mucosal Restoration in Women With Human Papillomavirus (HPV) | Atypical Squamous Cells of the Cervix, DNA Virus Infections, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Infections, Morphological and Microscopic Findings, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, Tumor Virus Infections, Urogenital Diseases, cervix disorder, dysplasia of cervix, female reproductive system disorder, human papilloma virus infection, infectious disease, neoplasm, precancerous condition, sexually transmitted disease, uterine disorder, viral infectious disease, viral sexually transmitted disease | Not yet recruiting | Not applicable | 2026-10-05 | NCT07762209 | |
| Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Head and Neck Neoplasms, Morphological and Microscopic Findings, Neoplasms by Site, Otorhinolaryngologic Neoplasms, Pathological Conditions, Signs and Symptoms, Pharyngeal Diseases, Squamous Intraepithelial Lesions, Stomatognathic Diseases, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, cervical squamous intraepithelial neoplasia, cervix disorder, dysplasia of cervix, female reproductive system disorder, female reproductive system neoplasm, neoplasm, otorhinolaryngologic disease, precancerous condition, uterine disorder | Enrolling by invitation | Not stated | 2026-10-02 | NCT04266093 | |
| CASCADE 2002: PROTECT Study, "PRObiotics to TrEat Anal preCancer Trial | High-Grade Squamous Intraepithelial Lesions, Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, human papillomavirus-related squamous cell carcinoma | Recruiting | Phase 2 | 2026-09-15 | NCT06949800 | |
| Hair Regrowth Following Partial Thickness Removal of SSCIS | Morphological and Microscopic Findings, Neoplasms by Histologic Type, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, Squamous Intraepithelial Lesions, alopecia, carcinoma, disorder of pilosebaceous unit, epithelial neoplasm, hypotrichosis, neoplasm, skin disorder, squamous cell carcinoma, squamous cell neoplasm | Not yet recruiting | Not applicable | 2026-09-09 | NCT07809191 | |
| Anal High-risk HPV, HSIL, and Microbiome Among Hispanic Peoples Living With HIV (PLWH) | AIDS, Blood-Borne Infections, Genital Diseases, HIV infectious disease, High-Grade Squamous Intraepithelial Lesions, Infections, Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, RNA Virus Infections, Slow Virus Diseases, Squamous Intraepithelial Lesions, Urogenital Diseases, immune system disorder, inborn error of immunity, infectious disease, lentivirus infection, sexually transmitted disease, uterine carcinosarcoma, viral infectious disease, viral sexually transmitted disease | Active, not recruiting | Not stated | 2026-08-20 | NCT06651957 | |
| Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV | AIDS, Blood-Borne Infections, Genital Diseases, HIV infectious disease, High-Grade Squamous Intraepithelial Lesions, Infections, Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, RNA Virus Infections, Slow Virus Diseases, Squamous Intraepithelial Lesions, Urogenital Diseases, immune system disorder, inborn error of immunity, infectious disease, lentivirus infection, sexually transmitted disease, uterine carcinosarcoma, viral infectious disease, viral sexually transmitted disease | Not yet recruiting | Phase 1 | 2026-08-18 | NCT06233331 | |
| Dual-Modality Immunotherapy for HPV Clearance (DUAL-HPV) | Atypical Squamous Cells of the Cervix, DNA Virus Infections, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Infections, Low-Grade Squamous Intraepithelial Lesions, Morphological and Microscopic Findings, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, Tumor Virus Infections, Urogenital Diseases, cervix disorder, dysplasia of cervix, female reproductive system disorder, human papilloma virus infection, infectious disease, neoplasm, precancerous condition, sexually transmitted disease, uterine disorder, viral infectious disease, viral sexually transmitted disease | Active, not recruiting | Not applicable | 2026-07-29 | NCT07735039 | |
| Evaluation of NWRD09 for HPV-16 Related Cervical HSIL | Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions | Not yet recruiting | Phase 2 | 2026-07-17 | NCT07712692 | |
| Hexaminolevulinate Photodynamic Therapy (HAL-PDT) With Deferred Surgery Versus Surgery for High-grade Squamous Intraepithelial Lesions (HSIL) | DNA Virus Infections, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Infections, Morphological and Microscopic Findings, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, Tumor Virus Infections, Urogenital Diseases, cervix disorder, dysplasia of cervix, female reproductive system disorder, human papilloma virus infection, infectious disease, neoplasm, precancerous condition, sexually transmitted disease, uterine disorder, viral infectious disease, viral sexually transmitted disease | Not yet recruiting | Phase 2 | 2026-07-09 | NCT07669363 | |
| Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women. | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Morphological and Microscopic Findings, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, cervix disorder, female reproductive system disorder, female reproductive system neoplasm, neoplasm, uterine disorder | Recruiting | Not stated | 2026-07-07 | NCT02956031 | |
| Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities | Atypical Squamous Cells of Undetermined Significance, Atypical Squamous Cells of the Cervix, DNA Virus Infections, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Infections, Low-Grade Squamous Intraepithelial Lesions, Morphological and Microscopic Findings, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, Tumor Virus Infections, Urogenital Diseases, cervix disorder, dysplasia of cervix, female reproductive system disorder, human papilloma virus infection, infectious disease, neoplasm, precancerous condition, sexually transmitted disease, uterine disorder, viral infectious disease, viral sexually transmitted disease | Recruiting | Phase 2 | 2026-05-14 | NCT07572396 | |
| Screening for Anal Cancer in Men Who Have Sex With Men Using Pre-Exposure Prophylaxis | Anal Cancer, Digestive System Diseases, Digestive System Neoplasms, High-Grade Squamous Intraepithelial Lesions, Low-Grade Squamous Intraepithelial Lesions, Morphological and Microscopic Findings, Neoplasms by Histologic Type, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, anus disorder, anus neoplasm, carcinoma, colorectal neoplasm, digestive system disorder, digestive system neoplasm, epithelial neoplasm, intestinal disorder, neoplasm, rectal disorder, rectal neoplasm, squamous cell carcinoma, squamous cell neoplasm | Recruiting | Not applicable | 2026-05-01 | NCT07029152 | |
| Comparison Between Liquid-Based Cytology And Molecular Screening For Detecting Precursor Lesions and Cervical Cancer | Atypical Squamous Cells of the Cervix, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Morphological and Microscopic Findings, Neoplasms by Site, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, cervix disorder, dysplasia of cervix, female reproductive system disorder, female reproductive system neoplasm, neoplasm, precancerous condition, uterine disorder | Recruiting | Not applicable | 2026-03-18 | NCT07480902 | |
| Trial to Evaluate Nonavalent HPV Vaccine as a Secondary Prevention in Patients Treated for Human Papilloma Virus Related High-grade Squamous Intraepithelial Lesions | Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions | Not yet recruiting | Phase 3 | 2026-02-27 | NCT07431502 | |
| A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV) | DNA Virus Infections, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Infections, Morphological and Microscopic Findings, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, Tumor Virus Infections, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, cervical squamous intraepithelial neoplasia, cervix disorder, dysplasia of cervix, female reproductive system disorder, female reproductive system neoplasm, human papilloma virus infection, infectious disease, neoplasm, precancerous condition, sexually transmitted disease, uterine disorder, viral infectious disease, viral sexually transmitted disease | Recruiting | Phase 4 | 2026-02-23 | NCT05334706 | |
| Evaluation of NWRD08 for HPV-16 and/or HPV-18 Related Cervical HSIL | Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions | Recruiting | Phase 2 | 2026-02-17 | NCT07175662 | |
| Study Assessing Reduced HPV Infectivity and Transmission in HPV-Positive Women Following Vaccination With 9vHPV | DNA Virus Infections, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Infections, Morphological and Microscopic Findings, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, Tumor Virus Infections, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, cervical squamous intraepithelial neoplasia, cervix disorder, dysplasia of cervix, female reproductive system disorder, female reproductive system neoplasm, human papilloma virus infection, infectious disease, neoplasm, precancerous condition, sexually transmitted disease, uterine disorder, viral infectious disease, viral sexually transmitted disease | Not yet recruiting | Phase 2 | 2026-02-11 | NCT07303751 | |
| Multicenter Prospective Non-randomized Controlled Study of Ella Photodynamic Therapy for Cervical HSIL/CIN2 | DNA Virus Infections, Disease Attributes, Genital Diseases, High-Grade Squamous Intraepithelial Lesions, Infections, Morphological and Microscopic Findings, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, Tumor Virus Infections, Urogenital Diseases, human papilloma virus infection, infectious disease, sexually transmitted disease, viral infectious disease, viral sexually transmitted disease | Not yet recruiting | Not applicable | 2025-12-29 | NCT07306260 | |
| Multicenter Prospective Non-randomized Controlled Study of ALA-PDT for LSIL With HPV16/18 Infection | Low-Grade Squamous Intraepithelial Lesions, Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions | Not yet recruiting | Not applicable | 2025-12-29 | NCT07306247 | |
| 5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer | Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions | Recruiting | Phase 2 / Phase 3 | 2025-11-28 | NCT05381597 | |
| NWRD09 for HPV-16 Related Cervical HSIL | Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions | Recruiting | Phase 1 | 2025-07-02 | NCT07047989 | |
| Comparison of 5-ALA Photodynamic Therapy and CO2 Laser for Treating Persistent Low-Grade Cervical Lesions With High-Risk HPV Infection | DNA Virus Infections, Disease Attributes, Genital Diseases, Infections, Low-Grade Squamous Intraepithelial Lesions, Morphological and Microscopic Findings, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, Tumor Virus Infections, Urogenital Diseases, human papilloma virus infection, infectious disease, sexually transmitted disease, viral infectious disease, viral sexually transmitted disease | Recruiting | Not applicable | 2025-05-13 | NCT06052033 | |
| Clinical Outcome and Biomarkers for Predicting Immunological Response in Patients Treated with Imiquimod | High-Grade Squamous Intraepithelial Lesions, Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions | Recruiting | Phase 4 | 2025-02-05 | NCT06356012 | |
| Predicting Treatment Failure in HSIL Patients with Positive Margins After Conization Via Detection of PAX1 Methylation | Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Margins of Excision, Morphological and Microscopic Findings, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, Squamous Intraepithelial Lesions, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, cervix disorder, dysplasia of cervix, female reproductive system disorder, female reproductive system neoplasm, neoplasm, precancerous condition, uterine disorder | Not yet recruiting | Not stated | 2024-12-06 | NCT06713655 | |
| Primary Cervical Cancer Screening by Self-sampling HPV Test | Atypical Squamous Cells of Undetermined Significance, Atypical Squamous Cells of the Cervix, Cervical Intraepithelial Neoplasia, Grade III, DNA Virus Infections, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, High-Grade Squamous Intraepithelial Lesions, Infections, Low-Grade Squamous Intraepithelial Lesions, Morphological and Microscopic Findings, Neoplasms by Histologic Type, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, Tumor Virus Infections, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, adenocarcinoma, adenocarcinoma in situ, carcinoma, cervical adenocarcinoma, cervical squamous cell carcinoma, cervical squamous intraepithelial neoplasia, cervix disorder, dysplasia of cervix, epithelial neoplasm, female reproductive system disorder, female reproductive system neoplasm, human papilloma virus infection, in situ carcinoma, infectious disease, neoplasm, precancerous condition, sexually transmitted disease, uterine disorder, viral infectious disease, viral sexually transmitted disease | Active, not recruiting | Not stated | 2023-12-21 | NCT05613283 |