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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United StatesDeglutition Disorders, Digestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, Pharyngeal Diseases, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorder, otorhinolaryngologic diseaseRecruitingNot applicable2026-10-09NCT07027826
A Trial of Upadacitinib for Non-responsive Eosinophilic EsophagitisDigestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderRecruitingPhase 22026-10-06NCT07588568
Natural History and Genetics of Food Allergy and Related ConditionsAbnormalities, Multiple, Aneurysm, Bone Diseases, Developmental, Camurati-Engelmann disease, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Digestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, Loeys-Dietz syndrome, Musculoskeletal Abnormalities, Skin Diseases, Eczematous, Skin and Connective Tissue Diseases, aortic aneurysm, aortic disorder, atopic eczema, bone disorder, cardiovascular disorder, dermatitis, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, food allergy, gastroenteritis, hematologic disorder, hereditary disease, hereditary skin disorder, immune system disorder, leukocyte disorder, musculoskeletal system disorder, osteochondrodysplasia, skin disorder, vascular disorderRecruitingNot stated2026-10-02NCT02504853
Using Spectrally Encoded Confocal Microscopy (SECM) to Image the EsophagusDigestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderActive, not recruitingNot applicable2026-10-02NCT02202590
A Study Assessing Esophageal Function and Remodeling With Dupilumab Compared With Placebo for 24 Weeks Followed by 104 Weeks Open Label in Adult Participants With EoE (REMOdeling With Dupilumab in Eosinophilic Esophagitis Long-term Trial)Digestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderActive, not recruitingPhase 42026-09-30NCT06101095
A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic EsophagitisDigestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderRecruitingPhase 32026-09-29NCT07112378
PPI Dosing Per CYP2C19 GenotypeDigestive System Diseases, digestive system disorder, duodenal disorder, esophageal disorder, esophagitis, gastroenteritis, intestinal disorder, peptic esophagitis, peptic ulcer disease, stomach disorderNot yet recruitingPhase 42026-09-28NCT07843264
Domperidone in Treating Patients With Gastrointestinal DisordersDeglutition Disorders, Digestive System Diseases, Heartburn, Nausea, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Signs and Symptoms, Digestive, Vomiting, digestive system disorder, dyskinesia of esophagus, dyspepsia, esophageal disorder, esophagitis, gastroenteritis, gastroesophageal reflux disease, gastroparesis, palsy, stomach disorderActive, not recruitingPhase 32026-09-24NCT01696734
Patient-Centered Decision Support for Eosinophilic EsophagitisDigestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderRecruitingNot applicable2026-09-23NCT06817213
Preoperative Predictors of Symptom Improvement After Laparoscopic FundoplicationBarrett esophagus, Deglutition Disorders, Digestive System Diseases, Hernia, Hernia, Diaphragmatic, Internal Hernia, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, digestive system disorder, duodenal disorder, dyskinesia of esophagus, esophageal disorder, esophagitis, gastroenteritis, gastroesophageal reflux disease, hiatus hernia, intestinal disorder, neoplasm, peptic esophagitis, peptic ulcer disease, precancerous condition, stomach disorderRecruitingNot stated2026-09-22NCT07809620
Molecular Basis of Food AllergyDigestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, food allergy, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderEnrolling by invitationNot stated2026-09-21NCT01832324
A Non-interventional Observational Study to Assess Long-term Efficacy and Safety of Dupilumab for the Treatment of Patients (>= 12 Years) With Eosinophilic Esophagitis Under Real-world-conditions in GermanyDigestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderRecruitingNot stated2026-09-17NCT06695897
Sino-Russian Comparison of Outcomes After Proximal Gastrectomy With Double-Tract ReconstructionDigestive System Diseases, digestive system disorder, duodenal disorder, esophageal disorder, esophagitis, gastric adenocarcinoma, gastroenteritis, gastroesophageal junction adenocarcinoma, intestinal disorder, peptic esophagitis, peptic ulcer disease, stomach disorderNot yet recruitingNot stated2026-09-02NCT07800819
The Potential Role of Compounds Derived From Ultra-processed Foods in Pathogenesis of Eosinophilic EsophagitisDigestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderRecruitingNot stated2026-09-01NCT06093204
Once Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoEDigestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderActive, not recruitingPhase 32026-08-28NCT06596252
The Johns Hopkins Heartburn Center RegistryBarrett esophagus, Deglutition Disorders, Digestive System Diseases, Laryngopharyngeal Reflux, digestive system disorder, dyskinesia of esophagus, esophageal disorder, esophagitis, gastroenteritis, gastroesophageal reflux disease, laryngeal disorder, neoplasm, precancerous condition, respiratory system disorderEnrolling by invitationNot stated2026-08-26NCT03853772
Impact of Body Positioning on EndoFLIP Measurements: A Comparative Study of Supine and Left Lateral Decubitus PositionsCongenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Deglutition Disorders, Digestive System Diseases, Eosinophilia, Esophageal Stenosis, Esophageal Stricture, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, Pharyngeal Diseases, Skin Abnormalities, Skin and Connective Tissue Diseases, achalasia, digestive system disorder, dyskinesia of esophagus, eosinophilic esophagitis, epidermolysis bullosa, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, hereditary disease, hereditary skin disorder, immune system disorder, leukocyte disorder, otorhinolaryngologic disease, skin disorder, vesiculobullous skin diseaseRecruitingNot applicable2026-08-24NCT07780981
Elimination Diet Strategies and Histologic Remission in Children With Eosinophilic Gastrointestinal DisordersDigestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderRecruitingNot stated2026-08-21NCT07779772
A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of CareDigestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderActive, not recruitingNot stated2026-08-12NCT06693531
A Prospective Cohort Study on Endoscopic Features of Upper Gastrointestinal Tract at High Altitude (Zaduo County)Digestive System Diseases, Hypoxia, Pathological Conditions, Signs and Symptoms, Respiration Disorders, Signs and Symptoms, Signs and Symptoms, Respiratory, altitude sickness, chronic atrophic gastritis, digestive system disorder, duodenal disorder, esophageal disorder, esophagitis, gastritis, gastroenteritis, intestinal disorder, peptic esophagitis, peptic ulcer disease, respiratory system disorder, stomach disorderRecruitingNot stated2026-08-10NCT07755384
Efficacy and Safety of Tezepelumab in Patients With Eosinophilic EsophagitisDigestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderActive, not recruitingPhase 32026-07-30NCT05583227
The DiNAM-EoE-C Study: Esophageal Distensibility and Novel Assessment of Motility in Eosinophilic EsophagitisDeglutition Disorders, Digestive System Diseases, Dilatation, Pathologic, Eosinophilia, Esophageal Dysphagia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Pharyngeal Diseases, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorder, otorhinolaryngologic diseaseEnrolling by invitationNot stated2026-07-29NCT07708467
PULSO Trial: Pulsed Low-Dose-Rate (PLDR) Radiation Chemoradiation (CRT) vs. Standard CRT for Esophageal CancerDigestive System Diseases, Digestive System Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Neoplasms by Site, digestive system disorder, digestive system neoplasm, esophageal cancer, esophageal disorder, esophagitis, gastroenteritis, gastroesophageal cancer, neoplasmRecruitingPhase 22026-07-28NCT06906887
Utility of Mucosal Impedance Device in Chronic Esophageal Disorders:Deglutition Disorders, Digestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, dyskinesia of esophagus, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, gastroesophageal reflux disease, hematologic disorder, immune system disorder, leukocyte disorderRecruitingNot stated2026-07-27NCT07227506
Surface EMG Testing on Swallowing in EoE PatientsDigestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorderActive, not recruitingNot stated2026-07-17NCT07156357