synostosis
synostosis
Explore linked clinical trials. Standard reference: MONDO:000141126 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Frontal Reconstruction Without Orbital Advancement for Moderate Metopic Craniosynostosis | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Metopic Synostosis, Musculoskeletal Abnormalities, Trigonocephaly, Nonsyndromic, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Not yet recruiting | Not applicable | 2026-09-23 | NCT07837453 | |
| Effects of Tummy Time Associated With Therapeutic Positioning in Premature Newborns With Cranial Asymmetry | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Female Urogenital Diseases and Pregnancy Complications, Musculoskeletal Abnormalities, Obstetric Labor Complications, Obstetric Labor, Premature, Plagiocephaly, Plagiocephaly, Nonsynostotic, Premature Birth, Urogenital Diseases, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, pregnancy disorder, synostosis | Not yet recruiting | Not applicable | 2026-09-18 | NCT07758426 | |
| Comparing Conservative to Surgical Treatment of Trigonocephaly Craniofacial Surgery in Children With Trigonocephaly: an Observational Cohort Study on Clinical Outcomes, Psychosocial Wellbeing, and Costs | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Metopic Synostosis, Musculoskeletal Abnormalities, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Recruiting | Not stated | 2026-09-11 | NCT06069479 | |
| ASO Treatment for Syndromic Craniosynostoses | Apert syndrome, Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Crouzon syndrome, Limb Deformities, Congenital, Muenke syndrome, Musculoskeletal Abnormalities, Pfeiffer syndrome, Saethre-Chotzen syndrome, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, syndactyly, synostosis | Recruiting | Not stated | 2026-09-08 | NCT07535372 | |
| Effectiveness of Repositioning and Cranial Remolding in Infants With Cranial Deformation | Bone Diseases, Developmental, Brachycephaly, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Dyskinesias, Musculoskeletal Abnormalities, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Plagiocephaly, Plagiocephaly, Nonsynostotic, Signs and Symptoms, bone disorder, craniosynostosis, dysostosis, dystonic disorder, inherited torticollis, musculoskeletal system disorder, synostosis | Recruiting | Not applicable | 2026-08-31 | NCT05917678 | |
| A Study of Erdafitinib Intravesical Delivery System in Japanese Participants With Bladder Cancer | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Limb Deformities, Congenital, Male Urogenital Diseases, Musculoskeletal Abnormalities, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, benign urinary system neoplasm, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, neoplasm, syndactyly, synostosis, urinary bladder disorder, urinary bladder neoplasm, urinary system disorder | Active, not recruiting | Phase 1 | 2026-08-28 | NCT05567185 | |
| Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Limb Deformities, Congenital, Musculoskeletal Abnormalities, Neoplasm Metastasis, Neoplasms by Histologic Type, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, adenocarcinoma, bone disorder, carcinoma, cholangiocarcinoma, craniosynostosis, dysostosis, epithelial neoplasm, intrahepatic cholangiocarcinoma, musculoskeletal system disorder, neoplasm, syndactyly, synostosis | Active, not recruiting | Phase 1 | 2026-08-05 | NCT06160752 | |
| Futibatinib (TAS-120) in Patients With Advanced Biliary Tract Cancer | Biliary Tract Neoplasms, Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Digestive System Diseases, Digestive System Neoplasms, Limb Deformities, Congenital, Musculoskeletal Abnormalities, Neoplasms by Site, autosomal dominant Parkinson disease 4, biliary tract cancer, biliary tract disorder, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, neoplasm, syndactyly, synostosis | Recruiting | Phase 3 | 2026-07-17 | NCT07710885 | |
| Pleth Variability Index Monitoring in Pediatric Craniosynostosis Surgery | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Musculoskeletal Abnormalities, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Recruiting | Not stated | 2026-06-18 | NCT07657598 | |
| Multimodal Mechanical, Tissue, Architectural, and Histological Evaluation of the Bone and Sutures of the Parietal Bone in an Infant With Craniosynostosis. | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Musculoskeletal Abnormalities, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Not yet recruiting | Not stated | 2026-06-16 | NCT07650981 | |
| Burosumab and 1-25 (OH) Vitamin D on Human Osteoblasts | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Musculoskeletal Abnormalities, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Recruiting | Not stated | 2026-04-16 | NCT04159675 | |
| Efficacy of Amicar for Children Having Craniofacial Surgery | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Musculoskeletal Abnormalities, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Active, not recruiting | Phase 2 | 2026-04-07 | NCT02229968 | |
| Ocular Characteristics in Patients With Craniosynostosis | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Musculoskeletal Abnormalities, Neurologic Manifestations, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, amblyopia, bone disorder, brain disorder, central nervous system disorder, cranial nerve neuropathy, craniosynostosis, dysostosis, eye disorder, intracranial hypertension, musculoskeletal system disorder, nervous system disorder, strabismus, synostosis, vision disorder | Recruiting | Not stated | 2026-02-12 | NCT06928727 | |
| A Phase 1b/2 Study of the Safety and Efficacy of the Monoclonal Antibody OM-RCA-01 in Patients With Metastatic Tumors Expressing Fibroblast Growth Factor Receptor 1 | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Head and Neck Neoplasms, Limb Deformities, Congenital, Male Urogenital Diseases, Musculoskeletal Abnormalities, Neoplasm Metastasis, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, Thoracic Neoplasms, Urogenital Diseases, Urogenital Neoplasms, benign urinary system neoplasm, bone disorder, breast disorder, breast neoplasm, craniosynostosis, dysostosis, kidney cancer, kidney disorder, lung disorder, lung neoplasm, male reproductive organ cancer, male reproductive system disorder, metastatic prostate carcinoma, musculoskeletal system disorder, neoplasm, prostate cancer, prostate disorder, respiratory system disorder, respiratory tract neoplasm, skin disorder, syndactyly, synostosis, urinary system disorder | Recruiting | Phase 1 / Phase 2 | 2026-01-21 | NCT07292168 | |
| Motiva Flora® Aesthetic Breast Recon® Clinical Study | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Limb Deformities, Congenital, Musculoskeletal Abnormalities, Neoplasms by Site, Poland syndrome, Skin and Connective Tissue Diseases, bone disorder, breast cancer, breast disorder, breast neoplasm, dysostosis, musculoskeletal system disorder, neoplasm, skin disorder, syndactyly, synostosis | Recruiting | Not applicable | 2025-11-26 | NCT06146231 | |
| Hemodynamic Monitoring During Craniosynostosis Surgery: Comparing Traditional and Newer Technology Monitors (CRASY-PRAM) | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Hemorrhage, Hypovolemia, Musculoskeletal Abnormalities, Pathologic Processes, Pathological Conditions, Signs and Symptoms, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Recruiting | Not stated | 2025-10-03 | NCT06263075 | |
| NCCH2006/MK010 Trial (FORTUNE Trial) | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Limb Deformities, Congenital, Musculoskeletal Abnormalities, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, syndactyly, synostosis | Recruiting | Phase 2 | 2025-10-03 | NCT04962867 | |
| Effects of Corrective Helmet Therapy on Cervical Motion and Thermoregulation in Children With Positional Deformities | Bone Diseases, Developmental, Brachycephaly, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Musculoskeletal Abnormalities, Plagiocephaly, Plagiocephaly, Nonsynostotic, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Not yet recruiting | Not stated | 2025-10-01 | NCT07201324 | |
| Early Genetic Identification of Obesity | Abnormalities, Multiple, Bardet-Biedl syndrome, Body Weight, Bone Diseases, Developmental, Ciliopathies, Cognition Disorders, Cognitive Dysfunction, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Hyperphagia, Limb Deformities, Congenital, Musculoskeletal Abnormalities, Nutritional and Metabolic Diseases, Overweight, Pathological Conditions, Signs and Symptoms, Pediatric Obesity, Signs and Symptoms, Signs and Symptoms, Digestive, bone disorder, brain disorder, central nervous system disorder, cognitive disorder, dysostosis, eye disorder, hereditary disease, hypothalamic disorder, musculoskeletal system disorder, nervous system disorder, nutritional disorder, obesity disorder, obesity due to pro-opiomelanocortin deficiency, overnutrition, polydactyly, psychiatric disorder, retinal disorder, retinitis pigmentosa, syndactyly, synostosis | Active, not recruiting | Not stated | 2025-09-29 | NCT06239064 | |
| Surgical Corection of Congenital Proximal Radioulnar Synostosis Using Double Osteotomy Technique. | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Musculoskeletal Abnormalities, bone disorder, dysostosis, musculoskeletal system disorder, synostosis | Not yet recruiting | Not applicable | 2025-09-09 | NCT07162233 | |
| Cranial Remolding Orthosis Registry | Bone Diseases, Developmental, Brachycephaly, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Musculoskeletal Abnormalities, Plagiocephaly, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Not yet recruiting | Not stated | 2025-01-07 | NCT06762691 | |
| Network Of Clinical Research Studies On Craniosynostosis, Skull Malformations With Premature Fusion Of Skull Bones | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Musculoskeletal Abnormalities, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Active, not recruiting | Not stated | 2025-01-02 | NCT03025763 | |
| EPBONF : Evaluation of the Safety and Effectiveness of a Medical Device Aimed at Guiding Orbito-naso-frontal Band Surgery, for the Treatment of Craniostenoses | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Musculoskeletal Abnormalities, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Not yet recruiting | Not applicable | 2024-04-15 | NCT06366178 | |
| Driving Pressure-guided Tidal Volume Ventilation in the Acute Respiratory Distress Syndrome | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Limb Deformities, Congenital, Lung Injury, Musculoskeletal Abnormalities, Respiration Disorders, Ventilator-Induced Lung Injury, adult acute respiratory distress syndrome, bone disorder, craniosynostosis, dysostosis, lung disorder, musculoskeletal system disorder, respiratory system disorder, syndactyly, synostosis | Not yet recruiting | Not applicable | 2024-03-26 | NCT06322758 | |
| GROWing Up With Rare GENEtic Syndromes | 22q11.2 deletion syndrome, 46 XY differences of sex development, 48,XXYY syndrome, Abnormalities, Multiple, Allan-Herndon-Dudley syndrome, Aortic Stenosis, Supravalvular, Bardet-Biedl syndrome, Blepharophimosis syndrome Ohdo type, Bone Diseases, Developmental, CHARGE syndrome, Cardiovascular Abnormalities, Ciliopathies, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Cytopenia, De Lange Syndrome, Deaf-Blind Disorders, Deafness, DiGeorge syndrome, Ear Diseases, Eye Diseases, Hereditary, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Hemic and Lymphatic Diseases, Imprinting Disorders, Jacobsen Distal 11q Deletion Syndrome, Kallmann syndrome, Klinefelter syndrome, Limb Deformities, Congenital, Lymphatic Abnormalities, Male Urogenital Diseases, Malformations of Cortical Development, Group I, Musculoskeletal Abnormalities, Neoplasms by Histologic Type, Neoplasms, Multiple Primary, Neoplasms, Nerve Tissue, Neurobehavioral Manifestations, Neurologic Manifestations, Noonan syndrome, Nutritional and Metabolic Diseases, Overweight, Pathological Conditions, Signs and Symptoms, Prader-Willi syndrome, Rett syndrome, Saethre-Chotzen syndrome, Sensation Disorders, Sex Chromosome Disorders, Signs and Symptoms, Skin and Connective Tissue Diseases, Turner syndrome, Urogenital Abnormalities, Urogenital Diseases, Williams syndrome, X-linked disease, adrenal gland disorder, adrenogenital syndrome, aortic valve disorder, aortic valve stenosis, blepharophimosis - intellectual disability syndrome, Ohdo type, blindness (disorder), blood platelet disease, bone disorder, brain disorder, cardiovascular disorder, central nervous system disorder, central nervous system malformation, cerebral cortical dysplasia, chromosomal disorder, coloboma, congenital adrenal hyperplasia, congenital heart disease, connective tissue disorder, craniosynostosis, disorder of sexual differentiation, dysostosis, endocrine system disorder, eye disorder, gonadal disorder, gonadal dysgenesis, hamartoma, hearing disorder, hearing loss disorder, heart disorder, heart valve disorder, hematologic disorder, hereditary disease, hereditary neoplastic syndrome, hypogonadism, hypoparathyroidism, hypothalamic disorder, inborn errors of metabolism, inherited neurodegenerative disorder, intellectual disability, lymphatic system disorder, metabolic disease, musculoskeletal system disorder, neoplasm, nerve sheath neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neurofibroma, neurofibromatosis, non-acquired combined pituitary hormone deficiency, nutritional disorder, obesity disorder, otorhinolaryngologic disease, overnutrition, parathyroid gland disorder, retinitis pigmentosa, sex chromosome disorder of sex development, steroid inherited metabolic disorder, syndactyly, synostosis, tetrasomy X, thrombocytopenia, tuberous sclerosis, velocardiofacial syndrome, vision disorder | Recruiting | Not stated | 2023-09-06 | NCT04463316 |