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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Lymphatic Abnormalities, Neoplasm, Lymphatic Tissue, Neoplasms by Histologic Type, cystic hygroma, lymphangioma, lymphatic system disorder, neoplasmRecruitingPhase 2 / Phase 32026-10-09NCT05948943
Radiological Diagnosis of Pediatric Neck SwellingsBranchial Cleft Anomalies, Branchioma, Cysts, Hemic and Lymphatic Diseases, Myosarcoma, Neoplasm, Lymphatic Tissue, Neoplasms by Histologic Type, Neoplasms, Adipose Tissue, Neoplasms, Connective and Soft Tissue, cystic hygroma, extraskeletal myxoid chondrosarcoma, hemangioma, lipoma, lymphadenitis, lymphangioma, lymphatic system disorder, myomatous neoplasm, myxoid chondrosarcoma, neoplasm, rhabdomyosarcoma, sarcoma, thyroglossal duct cyst, vascular cancerActive, not recruitingNot stated2026-07-30NCT07734805
A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular MalformationsCardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Lymphatic Abnormalities, Neoplasm, Lymphatic Tissue, Neoplasms by Histologic Type, PIK3CA-related overgrowth spectrum, Skin and Connective Tissue Diseases, arteriovenous hemangioma/malformation, cardiovascular disorder, cystic hygroma, lymphangioma, lymphatic malformation, lymphatic system disorder, neoplasm, skin disorder, skin vascular disease, vascular disorder, vascular malformation, venous hemangiomaRecruitingPhase 22026-05-05NCT05983159
SELVA: A Phase 3 Study Evaluating QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic MalformationsCardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Lymphatic Abnormalities, Neoplasm, Lymphatic Tissue, Neoplasms by Histologic Type, cardiovascular disorder, lymphangioma, lymphatic system disorder, microcystic lymphatic malformation, neoplasm, vascular malformationActive, not recruitingPhase 32026-03-27NCT06239480
A Study to Evaluate the Efficacy and Safety of Everolimus in Patients With Teratment-refractory Vascular AnomaliesCardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Neoplasm, Lymphatic Tissue, Neoplasms by Histologic Type, arteriovenous hemangioma/malformation, cardiovascular disorder, hemangioendothelioma, hemangioma, lymphangioma, melanocytic neoplasm, melanocytic nevus, neoplasm, vascular cancer, vascular disorder, vascular malformation, venous hemangiomaNot yet recruitingPhase 22026-03-17NCT07477548
Institution of an Italian Registry and Biobank for Biological Sample CollectionCongenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Lymphatic Abnormalities, Neoplasm, Lymphatic Tissue, Neoplasms by Histologic Type, lymphangioma, lymphatic malformation, lymphatic system disorder, neoplasmRecruitingNot applicable2025-03-25NCT06892964