optic nerve disorder
optic nerve disorder
Explore linked clinical trials. Standard reference: MONDO:0002135150 results · Page 1 of 6
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Hyperbaric Oxygen Therapy for Optic Neuropathies | cranial nerve neuropathy, eye disorder, glaucoma, nervous system disorder, ocular hypertension, optic nerve disorder | Recruiting | Not applicable | 2026-10-09 | NCT06128720 | |
| Natural History Study of Patients With Neurofibromatosis Type I | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Neoplasms, Fibrous Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, connective tissue neoplasm, cranial nerve neoplasm, cranial nerve neuropathy, epithelial neoplasm, eye disorder, fibrosarcoma, glioma, hereditary disease, hereditary neoplastic syndrome, inherited neurodegenerative disorder, neoplasm, nerve sheath neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neuroepithelial neoplasm, neurofibroma, neurofibromatosis, neurofibromatosis type 1, neurofibrosarcoma, neuromuscular disease, optic nerve disorder, optic nerve glioma, optic nerve neoplasm, peripheral nervous system disorder, peripheral nervous system neoplasm, plexiform neurofibroma, primitive neuroectodermal tumor, sarcoma | Active, not recruiting | Not stated | 2026-10-08 | NCT00924196 | |
| A Study to Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, and Pharmacodynamics of Satralizumab in Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD) | CNS demyelinating autoimmune disease, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, nervous system disorder, neuromyelitis optica, optic nerve disorder, optic neuritis | Recruiting | Phase 3 | 2026-10-01 | NCT05199688 | |
| NAION in Non-Diabetic Obese Patients Using GLP-1 Receptor Agonists: A Real-World Study | Body Weight, Nutritional and Metabolic Diseases, Optic Neuropathy, Ischemic, Overweight, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, cardiovascular disorder, cranial nerve neuropathy, eye disorder, nervous system disorder, nutritional disorder, obesity disorder, optic nerve disorder, overnutrition, vascular disorder | Not yet recruiting | Not stated | 2026-09-29 | NCT07846956 | |
| Prospective Evaluation of the 2022 Optic Neuritis Criteria When Optic Neuritis Is Suspected | Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, cranial nerve neuropathy, eye disorder, nervous system disorder, optic nerve disorder, optic neuritis, vision disorder | Recruiting | Not stated | 2026-09-25 | NCT07623252 | |
| Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX) | CNS demyelinating autoimmune disease, Infections, Neoplasms by Site, Neuroinflammatory Diseases, Paraneoplastic Syndromes, Nervous System, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, central nervous system disorder, central nervous system infectious disorder, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, myelitis, neoplasm, nervous system disorder, neurodegenerative disease, optic nerve disorder, optic neuritis, paraneoplastic syndrome, spinal cord disorder | Recruiting | Phase 3 | 2026-09-24 | NCT07100990 | |
| Effects of Different MAP Targets on Ocular Perfusion and Optic Nerve Microvasculature During Rhinoplasty | Optic Neuropathy, Ischemic, cardiovascular disorder, cranial nerve neuropathy, eye disorder, nervous system disorder, optic nerve disorder, vascular disorder | Recruiting | Not applicable | 2026-09-21 | NCT07832305 | |
| The Safety and Efficacy of NouvSoma001 in Neuromyelitis Optica Spectrum Disorders | CNS demyelinating autoimmune disease, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, nervous system disorder, neuromyelitis optica, optic nerve disorder, optic neuritis | Recruiting | Phase 1 | 2026-09-21 | NCT06620809 | |
| HANDLE-a Real World Study on Satralizumab in NMOSD | CNS demyelinating autoimmune disease, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, nervous system disorder, neuromyelitis optica, optic nerve disorder, optic neuritis | Recruiting | Not stated | 2026-09-18 | NCT06829524 | |
| SAD of IVT PYC-001 in OPA1 Mutation-Associated Autosomal Dominant Optic Atrophy (Sundew) | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Nutritional and Metabolic Diseases, Optic Atrophy, Autosomal Dominant, cranial nerve neuropathy, eye disorder, hereditary disease, hereditary optic atrophy, inborn mitochondrial metabolism disorder, inherited neurodegenerative disorder, metabolic disease, nervous system disorder, neurodegenerative disease, optic atrophy, optic nerve disorder | Active, not recruiting | Phase 1 | 2026-09-17 | NCT06461286 | |
| Dresden Glaucoma and Treatment Study (DGTS) | angle-closure glaucoma, eye disorder, glaucoma, low tension glaucoma, ocular hypertension, open-angle glaucoma, optic nerve disorder | Recruiting | Not stated | 2026-09-16 | NCT02959242 | |
| Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation | Diabetes Complications, cardiovascular disorder, diabetes mellitus, diabetic peripheral angiopathy, diabetic retinopathy, endocrine system disorder, eye disorder, glaucoma, low tension glaucoma, ocular hypertension, open-angle glaucoma, optic nerve disorder, retinal disorder, vascular disorder | Active, not recruiting | Phase 2 | 2026-09-14 | NCT07354477 | |
| A Study About the Safety of ASP2767 and Whether it Helps People With Glaucoma-Related Optic Nerve Damage | cranial nerve neuropathy, eye disorder, glaucoma, nervous system disorder, ocular hypertension, optic nerve disorder | Recruiting | Phase 1 / Phase 2 | 2026-09-11 | NCT07770685 | |
| Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity Study of Ravulizumab in Chinese Adults With Neuromyelitis Optica Spectrum Disorder (NMOSD) | CNS demyelinating autoimmune disease, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, nervous system disorder, neuromyelitis optica, optic nerve disorder, optic neuritis | Recruiting | Phase 3 | 2026-09-11 | NCT07557420 | |
| Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) | Optic Neuropathy, Ischemic, cardiovascular disorder, cranial nerve neuropathy, eye disorder, nervous system disorder, non-arteritic anterior ischemic optic neuropathy, optic nerve disorder, vascular disorder | Recruiting | Phase 3 | 2026-09-10 | NCT07453888 | |
| Efficacy and Safety of Low-Dose IL-2 in Neuromyelitis Optica Spectrum Disorder | CNS demyelinating autoimmune disease, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, nervous system disorder, neuromyelitis optica, optic nerve disorder, optic neuritis | Not yet recruiting | Phase 2 | 2026-09-09 | NCT07809724 | |
| A Safety and Efficacy Study Evaluating CTX112 in Subjects With Refractory Neurologic Autoimmune Disease | CNS demyelinating autoimmune disease, Chronic Disease, Disease Attributes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, autoimmune encephalitis, central nervous system disorder, chronic progressive multiple sclerosis, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, multiple sclerosis, myelin oligodendrocyte glycoprotein antibody-associated disease, nervous system disorder, neuromuscular disease, neuromyelitis optica, optic nerve disorder, optic neuritis, spinal cord disorder, stiff-person syndrome | Not yet recruiting | Phase 1 / Phase 2 | 2026-09-09 | NCT07804004 | |
| Emerging Indications for Hyperbaric Oxygen Treatment | Arterial Occlusive Diseases, Axonotmesis, Bacterial Infections and Mycoses, CNS demyelinating autoimmune disease, Clostridium Enterocolitis, Clostridium difficile colitis, Clostridium infectious disease, Cold Injury, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Conjunctival Diseases, Craniocerebral Trauma, Crohn disease, Crohn ileitis, Digestive System Diseases, Digestive System Fistula, Ear Diseases, Embolism and Thrombosis, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Fistula, Genital Diseases, Ileal Diseases, Infections, Invasive Fungal Infections, Male Urogenital Diseases, Necrosis, Neurologic Manifestations, Nonarteritic Anterior Ischemic Optic Neuropathy, Nutritional and Metabolic Diseases, Optic Neuropathy, Ischemic, Pathologic Processes, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Raynaud disease, Rectovaginal Fistula, Sensation Disorders, Signs and Symptoms, Skin Abnormalities, Skin Ulcer, Skin and Connective Tissue Diseases, Urogenital Abnormalities, Urogenital Diseases, Vaginal Fistula, Venous Thrombosis, anal fistula, autoimmune disease, autoimmune disorder of the nervous system, bacterial infectious disease, bone disorder, branch retinal artery occlusion, calcinosis, calciphylaxis, calcium metabolic disease, cardiovascular disorder, central retinal vein occlusion, colitis, colonic disorder, cranial nerve neuropathy, decubitus ulcer, demyelinating disease, digestive system disorder, enteritis, enterocolitis, epidermolysis bullosa, eye disorder, female reproductive system disorder, frostbite, fungal infectious disease, gastroenteritis, graft versus host disease, gram-positive bacterial infections, hearing disorder, hereditary disease, hereditary skin disorder, hypospadias, immune system disorder, inclusion body myositis, inflammatory bowel disease, injury, intestinal disorder, intestinal fistula, livedoid vasculopathy, male reproductive system disorder, malignant otitis externa, metabolic disease, multiple sclerosis, muscle tissue disorder, musculoskeletal system disorder, myositis disease, nervous system disorder, nervous system injury, neuromuscular disease, optic nerve disorder, osteonecrosis, otorhinolaryngologic disease, penile disorder, peripheral vascular disease, pouchitis, prosthesis-related infectious disease, pterygium, pyoderma, pyoderma gangrenosum, rectal disorder, retinal artery occlusion, retinal disorder, retinal vein occlusion, skin disorder, skin vascular disease, thrombotic disease, tinnitus, ulcerative colitis, vaginal disorder, vascular disorder, vesiculobullous skin disease | Not yet recruiting | Phase 4 | 2026-09-09 | NCT07240649 | |
| A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders | CNS demyelinating autoimmune disease, Chronic Disease, Disease Attributes, Neoplasms by Site, Paraneoplastic Syndromes, Nervous System, Pathologic Processes, Pathological Conditions, Signs and Symptoms, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, chronic inflammatory demyelinating polyradiculoneuropathy, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, multiple sclerosis, myasthenia gravis, neoplasm, nervous system disorder, neurodegenerative disease, neuromuscular disease, neuromuscular junction disease, neuromyelitis optica, optic nerve disorder, optic neuritis, paraneoplastic syndrome, peripheral nervous system disorder, polyneuropathy, polyradiculoneuropathy | Recruiting | Phase 1 | 2026-09-09 | NCT06680037 | |
| New Non-invasive Modalities for Assessing Retinal Structure and Function | Arterial Occlusive Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Hemianopsia, Leber hereditary optic neuropathy, Neurologic Manifestations, Nutritional and Metabolic Diseases, Optic Neuropathy, Ischemic, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, acute zonal occult outer retinopathy, blindness (disorder), branch retinal artery occlusion, cardiovascular disorder, cranial nerve neuropathy, eye disorder, hereditary disease, hereditary optic atrophy, inborn mitochondrial metabolism disorder, inherited neurodegenerative disorder, metabolic disease, nervous system disorder, neurodegenerative disease, optic atrophy, optic nerve disorder, retinal artery occlusion, retinal disorder, vascular disorder, vision disorder | Recruiting | Not applicable | 2026-09-08 | NCT03475173 | |
| Observational Safety Study in Women With Neuromyelitis Optica Spectrum Disorder (NMOSD) Exposed to UPLIZNA® During Pregnancy | CNS demyelinating autoimmune disease, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, nervous system disorder, neuromyelitis optica, optic nerve disorder, optic neuritis | Recruiting | Not stated | 2026-08-31 | NCT05909761 | |
| A Phase II Trial of G01 Eye Drops for Glaucomatous Optic Neuropathy | Cranial Nerve Injuries, Craniocerebral Trauma, cranial nerve neuropathy, eye disorder, glaucoma, injury, nervous system disorder, nervous system injury, ocular hypertension, open-angle glaucoma, optic nerve disorder, traumatic optic neuropathy | Recruiting | Phase 2 | 2026-08-24 | NCT07777861 | |
| Direct Selective Laser Trabeculoplasty in Ethnic Chinese Population | Glaucoma, Primary Open Angle, eye disorder, glaucoma, low tension glaucoma, ocular hypertension, open-angle glaucoma, optic nerve disorder | Active, not recruiting | Not applicable | 2026-08-17 | NCT05902871 | |
| Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation Research | CNS demyelinating autoimmune disease, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, autoimmune disease, autoimmune disorder of the nervous system, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, multiple sclerosis, nervous system disorder, optic nerve disorder, optic neuritis, vision disorder | Recruiting | Phase 3 | 2026-08-14 | NCT07623668 | |
| A Multicenter Prospective Real-World Effectiveness and Safety of Satralizumab in the Early Treatment of Attacks in NMOSD | CNS demyelinating autoimmune disease, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, nervous system disorder, neuromyelitis optica, optic nerve disorder, optic neuritis | Recruiting | Not stated | 2026-08-13 | NCT07762872 |