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primary central nervous system lymphoma

primary central nervous system lymphoma

Explore linked clinical trials. Standard reference: MONDO:0002571
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Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Phase I Study Evaluating Tolerability, Safety, Pharmacokinetics, and Efficacy of Combined ONO-4059 and R-MPV Therapy for PCNSLprimary central nervous system lymphomaActive, not recruitingPhase 12026-10-06NCT06541665
Rapid Diagnosis and Treatment Response Monitoring of Primary CNS Lymphoma Using CSF ctDNA Liquid Biopsyprimary central nervous system lymphomaRecruitingNot stated2026-10-01NCT07851363
T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)B-cell neoplasm, B-cell non-Hodgkin lymphoma, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, high grade B-cell lymphoma, immune system disorder, immunoproliferative disorder, large B-cell lymphoma, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, neoplasm, non-Hodgkin lymphoma, primary central nervous system lymphoma, primary effusion lymphomaRecruitingPhase 1 / Phase 22026-10-01NCT06343311
Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (TEDDI-R) in Primary CNS Lymphomaprimary central nervous system lymphomaActive, not recruitingPhase 12026-09-30NCT02203526
Maintenance Obinutuzumab in Treating Patients With Central Nervous System Lymphoma Who Have Achieved a Complete or Partial Responseprimary central nervous system lymphomaRecruitingPhase 22026-09-23NCT06175000
Acalabrutinib and Durvalumab in Primary and Secondary Central Nervous System Lymphomaprimary central nervous system lymphomaActive, not recruitingPhase 12026-09-16NCT04462328
Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas With Secondary Involvement of the Central Nervous System (CNS)primary central nervous system lymphomaActive, not recruitingPhase 22026-09-04NCT03964090
19(T2)28z1xx Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell CancersB-cell chronic lymphocytic leukemia, B-cell neoplasm, Blood Protein Disorders, Burkitt lymphoma, Chronic Disease, DNA Virus Infections, Disease Attributes, Epstein-Barr virus infection, Hemic and Lymphatic Diseases, Herpesviridae infectious disease, Infections, Leukemia, B-Cell, Lymphoma, B-Cell, Marginal Zone, Neoplasms by Histologic Type, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Tumor Virus Infections, Waldenstrom macroglobulinemia, cardiovascular disorder, diffuse large B-cell lymphoma, hematologic disorder, hemorrhagic disease, immune system disorder, immunoproliferative disorder, leukemia, lymphatic system disorder, lymphoid leukemia, lymphoma, lymphoproliferative syndrome, marginal zone lymphoma, monoclonal gammopathy, neoplasm, plasma cell neoplasm, primary central nervous system lymphoma, vascular disorder, vascular hemostatic disease, viral infectious diseaseActive, not recruitingPhase 12026-08-27NCT04464200
Golcadomide With Pemetrexed, Rituximab, and Dexamethasone for Relapsed and Refractory CNS Lymphomaslarge B-cell lymphoma, primary central nervous system lymphomaNot yet recruitingPhase 12026-08-21NCT07608731
Orelabrutinib Combined With Teniposide, Rituximab and Methotrexate for Newly Diagnosed PCNSLprimary central nervous system lymphomaRecruitingPhase 2 / Phase 32026-08-19NCT07185373
R-MA-PD-1 Versus R-MA in Treatment-naive Primary CNS LymphomaB-cell neoplasm, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, diffuse large B-cell lymphoma, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, neoplasm, primary central nervous system lymphomaNot yet recruitingNot applicable2026-08-14NCT07764601
MIDNOR-STROKE- a Long Term Follow-up Study of Patients With First Ever Ischemic Stroke in Central NorwayPathologic Processes, Pathological Conditions, Signs and Symptoms, brain disorder, brain ischemia, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, depressive disorder, nervous system disorder, primary central nervous system lymphoma, stroke disorder, vascular disorderActive, not recruitingNot stated2026-08-13NCT03962127
Immunotherapy Using CAR T-cells to Target CD19 for Relapsed/Refractory CD19+ Primary CNS Lymphomaprimary central nervous system lymphomaActive, not recruitingPhase 12026-08-11NCT04443829
Loncastuximab Tesirine and Rituximab Following Stereotactic Radiosurgery in Patients With Central Nervous System Lymphomas (SOLAR)primary central nervous system lymphomaRecruitingPhase 12026-08-10NCT06607549
Tirabrutinib Maintenance Versus Placebo in Patients With Primary CNS Lymphoma in Complete Remission (JCOG2104)primary central nervous system lymphomaRecruitingPhase 22026-08-05NCT06940791
Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFUB-cell neoplasm, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, diffuse large B-cell lymphoma, high grade B-cell lymphoma, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, neoplasm, non-Hodgkin lymphoma, primary central nervous system lymphomaRecruitingNot stated2026-08-05NCT06116110
Paxalisib (GDC-0084) In Recurrent Or Refractory PCNSLprimary central nervous system lymphomaRecruitingPhase 22026-08-05NCT04906096
Neurocognitive Assessment CNSL and LGGCognition Disorders, Cognitive Dysfunction, Neoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, cognitive disorder, low grade glioma, neoplasm, nervous system disorder, primary central nervous system lymphoma, psychiatric disorderNot yet recruitingNot applicable2026-07-17NCT07710131
A Study of Epcoritamab and Ibrutinib in People With Central Nervous System Lymphoma (CNSL)primary central nervous system lymphomaRecruitingPhase 12026-07-14NCT07082868
Tafasitamab Plus Lenalidomide in Relapsed CNS Lymphomaprimary central nervous system lymphomaRecruitingPhase 1 / Phase 22026-07-14NCT05351593
Feasibility of Acquiring Hyperpolarized Imaging in Patients With Primary CNS Lymphomaprimary central nervous system lymphomaRecruitingPhase 12026-07-14NCT04656431
DALY II USA/ MB-CART2019.1 for DLBCLB-cell neoplasm, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Richter transformation, central nervous system cancer, diffuse large B-cell lymphoma, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, mantle cell lymphoma, neoplasm, nervous system disorder, primary central nervous system lymphomaRecruitingPhase 22026-07-13NCT04792489
Preliminary Safety and Tolerability of CD19x22 CAR T Cells in Adolescent and Adult R/R B-NHL PatientsB-cell neoplasm, Disease Attributes, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, mantle cell lymphoma, neoplasm, non-Hodgkin lymphoma, primary central nervous system lymphomaRecruitingPhase 12026-07-09NCT05098613
Acalabrutinib in CNSLprimary central nervous system lymphomaActive, not recruitingPhase 1 / Phase 22026-06-17NCT04906902
A Pilot Study of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS Lymphomasprimary central nervous system lymphomaActive, not recruitingPhase 22026-06-10NCT04548648