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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of NIO752 in Primary TauopathiesFrontotemporal Lobar Degeneration, Neurologic Manifestations, Nutritional and Metabolic Diseases, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Pick disease, Signs and Symptoms, TDP-43 proteinopathy, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, corticobasal degeneration disorder, cranial nerve neuropathy, dementia, eye disorder, frontotemporal dementia, metabolic disease, movement disorder, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, progressive supranuclear palsy, proteostasis deficiencies, psychiatric disorder, tauopathyNot yet recruitingPhase 22026-10-09NCT07868328
The Progressive Supranuclear Palsy Clinical Trial PlatformNeurologic Manifestations, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, cranial nerve neuropathy, eye disorder, movement disorder, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, tauopathyRecruitingPhase 22026-10-09NCT07173803
Hyperbaric Oxygen Therapy for Optic Neuropathiescranial nerve neuropathy, eye disorder, glaucoma, nervous system disorder, ocular hypertension, optic nerve disorderRecruitingNot applicable2026-10-09NCT06128720
Natural History Study of Patients With Neurofibromatosis Type ICongenital, Hereditary, and Neonatal Diseases and Abnormalities, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Neoplasms, Fibrous Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, connective tissue neoplasm, cranial nerve neoplasm, cranial nerve neuropathy, epithelial neoplasm, eye disorder, fibrosarcoma, glioma, hereditary disease, hereditary neoplastic syndrome, inherited neurodegenerative disorder, neoplasm, nerve sheath neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neuroepithelial neoplasm, neurofibroma, neurofibromatosis, neurofibromatosis type 1, neurofibrosarcoma, neuromuscular disease, optic nerve disorder, optic nerve glioma, optic nerve neoplasm, peripheral nervous system disorder, peripheral nervous system neoplasm, plexiform neurofibroma, primitive neuroectodermal tumor, sarcomaActive, not recruitingNot stated2026-10-08NCT00924196
Tributyrin for Progressive Supranuclear Palsy (PSP): Virtual TrialNeurologic Manifestations, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cranial nerve neuropathy, eye disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, synucleinopathy, tauopathyRecruitingPhase 1 / Phase 22026-10-07NCT07863180
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)Frontotemporal Lobar Degeneration, Neurologic Manifestations, Nutritional and Metabolic Diseases, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, amyotrophic lateral sclerosis, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, corticobasal degeneration disorder, cranial nerve neuropathy, dementia, eye disorder, frontotemporal dementia, frontotemporal dementia with motor neuron disease, metabolic disease, motor neuron disorder, movement disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, ophthalmoplegia, palsy, proteostasis deficiencies, psychiatric disorder, spinal cord disorder, tauopathyRecruitingNot stated2026-10-07NCT04363684
Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing TumorsCarcinoma, Medullary, DNA Virus Infections, Esthesioneuroblastoma, Olfactory, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Infections, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Ductal, Lobular, and Medullary, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Skin and Connective Tissue Diseases, Thoracic Neoplasms, Tumor Virus Infections, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, adenocarcinoma, astrocytoma (excluding glioblastoma), benign urinary system neoplasm, bronchial neoplasm, bronchogenic carcinoma, carcinoma, cervix disorder, cranial nerve neuropathy, cutaneous neuroendocrine carcinoma, endocrine system disorder, epithelial neoplasm, female reproductive system disorder, female reproductive system neoplasm, glioblastoma, glioma, gonadal disorder, lung disorder, lung neoplasm, male reproductive organ cancer, male reproductive system disorder, malignant endocrine neoplasm, medullary thyroid gland carcinoma, melanocytic neoplasm, melanoma, neoplasm, nervous system disorder, neuroblastoma, neuroendocrine carcinoma, neuroendocrine neoplasm, neuroepithelial neoplasm, non-small cell lung carcinoma, olfactory nerve disorder, polyomavirus infectious disease, primitive neuroectodermal tumor, pulmonary large cell neuroendocrine carcinoma, respiratory system disorder, respiratory tract neoplasm, sinonasal undifferentiated carcinoma, skin disorder, skin neoplasm, testicular cancer, testicular disorder, urinary bladder cancer, urinary bladder disorder, urinary bladder neoplasm, urinary system disorder, uterine disorder, viral infectious diseaseRecruitingPhase 1 / Phase 22026-10-06NCT06814496
[212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck CancersEsthesioneuroblastoma, Olfactory, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Head and Neck Neoplasms, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Otorhinolaryngologic Neoplasms, Pharyngeal Diseases, Stomatognathic Diseases, Urogenital Diseases, Urogenital Neoplasms, benign urinary system neoplasm, carcinoma, cranial nerve neuropathy, epithelial neoplasm, kidney cancer, kidney disorder, nasopharyngeal carcinoma, nasopharyngeal disorder, nasopharyngeal neoplasm, neoplasm, nervous system disorder, neuroblastoma, neuroendocrine neoplasm, neuroepithelial neoplasm, olfactory nerve disorder, otorhinolaryngologic disease, paraganglioma, pheochromocytoma, primitive neuroectodermal tumor, urinary system disorderRecruitingPhase 12026-10-06NCT06479811
A Phase 2 Study Of Zanzalintinib For Patients With Recurrent Or Metastatic Olfactory NeuroblastomaEsthesioneuroblastoma, Olfactory, Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, cranial nerve neuropathy, epithelial neoplasm, neoplasm, nervous system disorder, neuroblastoma, neuroepithelial neoplasm, olfactory nerve disorder, primitive neuroectodermal tumorNot yet recruitingPhase 22026-10-05NCT07527169
Art Therapy in Progressive Supranuclear PalsyNeurologic Manifestations, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, cranial nerve neuropathy, eye disorder, movement disorder, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, progressive supranuclear palsy, tauopathyActive, not recruitingNot applicable2026-10-05NCT06588673
Natural History Study of Patients With Neurofibromatosis Type 2Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Ear Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Otorhinolaryngologic Neoplasms, acoustic neuroma, central nervous system cancer, central nervous system disorder, cranial nerve neoplasm, cranial nerve neuropathy, ependymoma, epithelial neoplasm, glioma, hereditary disease, hereditary neoplastic syndrome, inherited neurodegenerative disorder, meningioma, neoplasm, nerve sheath neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neuroendocrine neoplasm, neuroepithelial neoplasm, neurofibroma, neurofibromatosis, neuroma, otorhinolaryngologic disease, peripheral nervous system neoplasm, primitive neuroectodermal tumor, retrocochlear disease, schwannoma, spinal cord disorder, spinal cord neoplasm, tumor of meninges, vascular cancer, vestibulocochlear nerve disorderRecruitingNot stated2026-10-02NCT00598351
A Study to Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, and Pharmacodynamics of Satralizumab in Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)CNS demyelinating autoimmune disease, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, nervous system disorder, neuromyelitis optica, optic nerve disorder, optic neuritisRecruitingPhase 32026-10-01NCT05199688
NAION in Non-Diabetic Obese Patients Using GLP-1 Receptor Agonists: A Real-World StudyBody Weight, Nutritional and Metabolic Diseases, Optic Neuropathy, Ischemic, Overweight, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, cardiovascular disorder, cranial nerve neuropathy, eye disorder, nervous system disorder, nutritional disorder, obesity disorder, optic nerve disorder, overnutrition, vascular disorderNot yet recruitingNot stated2026-09-29NCT07846956
Wellness in PSP and CBDNeurologic Manifestations, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, corticobasal degeneration disorder, cranial nerve neuropathy, eye disorder, movement disorder, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, progressive supranuclear palsy, tauopathyRecruitingNot applicable2026-09-28NCT07844655
3D MRE-Based Evaluation of Vestibular Schwannoma Mechanical Properties and Histological FeaturesEar Diseases, Fibrosis, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Otorhinolaryngologic Neoplasms, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Tissue Adhesions, acoustic neuroma, cranial nerve neoplasm, cranial nerve neuropathy, neoplasm, nerve sheath neoplasm, nervous system disorder, neuroendocrine neoplasm, neuroma, otorhinolaryngologic disease, peripheral nervous system neoplasm, primitive neuroectodermal tumor, retrocochlear disease, schwannoma, severe cutaneous adverse reaction, vestibulocochlear nerve disorderEnrolling by invitationNot stated2026-09-28NCT07844460
Treatment for "Asymmetric Crying Facies"Bell's palsy, Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Crouzon syndrome, DNA Virus Infections, Herpesviridae infectious disease, Infections, Musculoskeletal Abnormalities, Stomatognathic Diseases, bone disorder, cranial nerve neuropathy, craniofacial microsomia, dysostosis, facial nerve disorder, mandibulofacial dysostosis, mouth disorder, musculoskeletal system disorder, nervous system disorder, viral infectious diseaseRecruitingNot applicable2026-09-28NCT07802639
Prospective Evaluation of the 2022 Optic Neuritis Criteria When Optic Neuritis Is SuspectedNeurologic Manifestations, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, cranial nerve neuropathy, eye disorder, nervous system disorder, optic nerve disorder, optic neuritis, vision disorderRecruitingNot stated2026-09-25NCT07623252
Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)CNS demyelinating autoimmune disease, Infections, Neoplasms by Site, Neuroinflammatory Diseases, Paraneoplastic Syndromes, Nervous System, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, central nervous system disorder, central nervous system infectious disorder, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, myelitis, neoplasm, nervous system disorder, neurodegenerative disease, optic nerve disorder, optic neuritis, paraneoplastic syndrome, spinal cord disorderRecruitingPhase 32026-09-24NCT07100990
A Feedback-enabled Magnetic Device for Temporary Management of BlepharoptosisOcular Motility Disorders, cranial nerve neuropathy, eye disorder, eyelid disorder, nervous system disorder, ptosis, third cranial nerve disorderRecruitingNot applicable2026-09-23NCT03812016
Single Dose 4-Aminopyridine for Diagnosing Recurrent Laryngeal Nerve Paralysis Continuity After TraumaLaryngeal Nerve Palsy, Recurrent, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Vocal Cord Paralysis, cranial nerve neuropathy, laryngeal disorder, nervous system disorder, otorhinolaryngologic disease, palsy, respiratory system disorder, vagus nerve disorderNot yet recruitingPhase 12026-09-21NCT07832331
Effects of Different MAP Targets on Ocular Perfusion and Optic Nerve Microvasculature During RhinoplastyOptic Neuropathy, Ischemic, cardiovascular disorder, cranial nerve neuropathy, eye disorder, nervous system disorder, optic nerve disorder, vascular disorderRecruitingNot applicable2026-09-21NCT07832305
Proactively Intervening On Early Cranial Nerve Injury As A Delayed Sequela Of Oropharyngeal Cancer: A Randomized Feasibility Clinical Trial For Pro-Habilitation (proNERVE RCT)Cranial Nerve Injuries, Craniocerebral Trauma, Head and Neck Neoplasms, Neoplasms by Site, Otorhinolaryngologic Neoplasms, Pharyngeal Diseases, Stomatognathic Diseases, cranial nerve neuropathy, injury, neoplasm, nervous system disorder, nervous system injury, otorhinolaryngologic diseaseNot yet recruitingPhase 12026-09-21NCT07832266
The Safety and Efficacy of NouvSoma001 in Neuromyelitis Optica Spectrum DisordersCNS demyelinating autoimmune disease, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, nervous system disorder, neuromyelitis optica, optic nerve disorder, optic neuritisRecruitingPhase 12026-09-21NCT06620809
Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base TumorsEsthesioneuroblastoma, Olfactory, Neoplasms by Histologic Type, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, chondrosarcoma, connective tissue neoplasm, cranial nerve neuropathy, epithelial neoplasm, neoplasm, nervous system disorder, neuroblastoma, neuroepithelial neoplasm, olfactory nerve disorder, primitive neuroectodermal tumor, sarcoma, sinonasal undifferentiated carcinomaRecruitingPhase 22026-09-21NCT06176989
VisMemoPD Protocol: an Observational Pilot Study on Spatial and Topographical Memory in Patients With Parkinson's Disease and ParkinsonismCognition Disorders, Cognitive Dysfunction, Mild Cognitive Impairment, Neurologic Manifestations, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, cranial nerve neuropathy, eye disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, progressive supranuclear palsy, psychiatric disorder, synucleinopathy, tauopathyNot yet recruitingNot stated2026-09-18NCT07827963