diffuse scleroderma
diffuse scleroderma
Explore linked clinical trials. Standard reference: MONDO:000501975 results · Page 1 of 3
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| A Phase 1/2 Study of PRO-203 in Healthy Volunteers and Participants With Systemic Sclerosis. | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, scleroderma, skin disorder, systemic sclerosis | Recruiting | Phase 1 / Phase 2 | 2026-10-09 | NCT07641634 | |
| The Effect of Progressive Muscle Relaxation Exercises on Fatigue, Dyspnea, and Respiratory Function in Patients With Systemic Sclerosis | Dyspnea, Fatigue, Pathological Conditions, Signs and Symptoms, Respiration Disorders, Signs and Symptoms, Signs and Symptoms, Respiratory, Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, respiratory system disorder, skin disorder, systemic sclerosis | Recruiting | Not applicable | 2026-10-08 | NCT07842133 | |
| EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc) | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, skin disorder, systemic sclerosis | Recruiting | Phase 2 | 2026-10-05 | NCT07287670 | |
| A Phase 1b Study of C-CAR168 in Participants With Systemic Sclerosis (SSc) | Skin and Connective Tissue Diseases, autoimmune disease, connective tissue disorder, diffuse scleroderma, immune system disorder, skin disorder, systemic sclerosis | Not yet recruiting | Phase 1 | 2026-10-02 | NCT07854483 | |
| Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, skin disorder, systemic sclerosis | Recruiting | Phase 2 | 2026-10-01 | NCT04986605 | |
| Comparative Autoantibody and Immunologic Cell Marker Study | AIDS, Blood-Borne Infections, Chronic Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cytopenia, DNA Virus Infections, Digestive System Diseases, Disease Attributes, Epstein-Barr virus infection, Flaviviridae infectious disease, Genital Diseases, Guillain-Barre syndrome, HIV infectious disease, Hemic and Lymphatic Diseases, Hemorrhage, Herpesviridae infectious disease, Immunoglobulin G4-Related Disease, Infections, Inflammation, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Post-Infectious Disorders, Purpura, Thrombocytopenic, Idiopathic, RNA Virus Infections, Sepsis, Signs and Symptoms, Sjogren syndrome, Skin Manifestations, Skin and Connective Tissue Diseases, Slow Virus Diseases, Stomatognathic Diseases, Systemic Inflammatory Response Syndrome, Tumor Virus Infections, Undifferentiated Connective Tissue Diseases, Urogenital Diseases, Xerostomia, arthritic joint disease, arthropathy, autoimmune disease, autoimmune disorder of the nervous system, autoimmune lymphoproliferative syndrome, blood coagulation disease, blood platelet disease, connective tissue disorder, demyelinating disease, diffuse scleroderma, dry eye syndrome, eye disorder, graft versus host disease, hematologic disorder, hemorrhagic disease, hepatitis, hepatitis C virus infection, hereditary disease, immune system disorder, immunoproliferative disorder, inborn error of immunity, infectious disease, juvenile idiopathic arthritis, lacrimal apparatus disorder, lentivirus infection, liver disorder, lymphatic system disorder, lymphoproliferative syndrome, mouth disorder, muscle tissue disorder, musculoskeletal system disorder, myositis disease, nervous system disorder, neuromuscular disease, peripheral nervous system disorder, polyneuropathy, polyradiculoneuropathy, purpura, rheumatic disorder, rheumatoid arthritis, salivary gland disorder, sexually transmitted disease, skin disorder, systemic lupus erythematosus, systemic sclerosis, thrombocytopenia, thrombocytopenic purpura, thrombotic microangiopathy, uterine carcinosarcoma, viral hepatitis, viral infectious disease, viral sexually transmitted disease | Enrolling by invitation | Not stated | 2026-10-01 | NCT02422875 | |
| Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY) | Skin and Connective Tissue Diseases, autoimmune disease, connective tissue disorder, diffuse scleroderma, immune system disorder, interstitial lung disease, lung disorder, respiratory system disorder, scleroderma, skin disorder, systemic sclerosis | Active, not recruiting | Phase 3 | 2026-09-30 | NCT05925803 | |
| A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, skin disorder, systemic sclerosis | Recruiting | Phase 2 | 2026-09-28 | NCT06470048 | |
| Sildenafil for Early Pulmonary Vascular Disease in Scleroderma | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, scleroderma, skin disorder, systemic sclerosis | Recruiting | Phase 2 | 2026-09-28 | NCT04797286 | |
| Home-based Exercise for Improving Health-related Quality of Life in Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, skin disorder, systemic sclerosis | Not yet recruiting | Not applicable | 2026-09-25 | NCT07840430 | |
| Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Systemic Sclerosis Associated With Interstitial Lung Disease (SSc-ILD) (MK-7240-007) | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, interstitial lung disease, lung disorder, respiratory system disorder, skin disorder, systemic sclerosis | Active, not recruiting | Phase 2 | 2026-09-22 | NCT05270668 | |
| CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101 | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Skin and Connective Tissue Diseases, Urogenital Diseases, acquired idiopathic inflammatory myopathy, anti-neutrophil cytoplasmic antibody-associated vasculitis, autoimmune disease, cardiovascular disorder, connective tissue disorder, diffuse scleroderma, glomerulonephritis, immune system disorder, kidney disorder, lupus nephritis, muscle tissue disorder, musculoskeletal system disorder, myositis disease, necrotizing vasculitis, nephritis, nervous system disorder, neuromuscular disease, skin disorder, skin vascular disease, systemic lupus erythematosus, systemic sclerosis, urinary system disorder, vascular disorder, vasculitis | Active, not recruiting | Phase 1 | 2026-09-21 | NCT06152172 | |
| Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis | Pathologic Processes, Pathological Conditions, Signs and Symptoms, Sclerosis, Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, digital ulcers, skin disorder, systemic sclerosis | Recruiting | Not applicable | 2026-09-11 | NCT06256575 | |
| A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Skin and Connective Tissue Diseases, Urogenital Diseases, autoimmune disease, connective tissue disorder, dermatomyositis, diffuse scleroderma, glomerulonephritis, immune system disorder, kidney disorder, lupus nephritis, muscle tissue disorder, musculoskeletal system disorder, myositis disease, nephritis, nervous system disorder, neuromuscular disease, polymyositis, skin disorder, systemic lupus erythematosus, systemic sclerosis, urinary system disorder | Recruiting | Phase 1 | 2026-09-10 | NCT07085104 | |
| A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE) | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, interstitial lung disease, lung disorder, respiratory system disorder, skin disorder, systemic sclerosis | Recruiting | Phase 3 | 2026-09-09 | NCT06716606 | |
| A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, interstitial lung disease, lung disorder, respiratory system disorder, skin disorder, systemic sclerosis | Recruiting | Phase 2 / Phase 3 | 2026-09-08 | NCT05878717 | |
| Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, skin disorder, systemic sclerosis | Active, not recruiting | Phase 2 | 2026-09-02 | NCT06655896 | |
| Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension | Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, autoimmune disease, connective tissue disorder, diffuse scleroderma, immune system disorder, limited cutaneous systemic sclerosis, skin disorder, systemic sclerosis | Active, not recruiting | Phase 2 | 2026-09-02 | NCT02682511 | |
| A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Skin and Connective Tissue Diseases, Urogenital Diseases, acquired idiopathic inflammatory myopathy, autoimmune disease, connective tissue disorder, diffuse scleroderma, glomerulonephritis, immune system disorder, kidney disorder, lupus nephritis, muscle tissue disorder, musculoskeletal system disorder, myositis disease, nephritis, nervous system disorder, neuromuscular disease, skin disorder, systemic lupus erythematosus, systemic sclerosis, urinary system disorder | Recruiting | Phase 1 | 2026-08-28 | NCT06925542 | |
| Controlling Hyperactive Immunity With Long-lived Lymphocytes | Skin and Connective Tissue Diseases, arthritic joint disease, arthropathy, autoimmune disease, connective tissue disorder, diffuse scleroderma, immune system disorder, musculoskeletal system disorder, rheumatic disorder, rheumatoid arthritis, skin disorder, systemic sclerosis | Recruiting | Phase 1 / Phase 2 | 2026-08-21 | NCT07473154 | |
| Periodontal Microbiota in Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, skin disorder, systemic sclerosis | Recruiting | Not applicable | 2026-08-19 | NCT06182293 | |
| Platform Clinical Study for Conquering Scleroderma | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, interstitial lung disease, lung disorder, respiratory system disorder, scleroderma, skin disorder, systemic sclerosis | Recruiting | Phase 2 | 2026-08-18 | NCT06195072 | |
| RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis | Skin and Connective Tissue Diseases, autoimmune disease, connective tissue disorder, diffuse scleroderma, immune system disorder, interstitial lung disease, lung disorder, respiratory system disorder, scleroderma, skin disorder, systemic sclerosis | Recruiting | Phase 2 / Phase 3 | 2026-08-17 | NCT06328777 | |
| DERMATOMICS: Identifying Regulators of Skin Homeostasis | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, skin disorder, systemic sclerosis | Recruiting | Not stated | 2026-08-14 | NCT06894654 | |
| Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis | Skin and Connective Tissue Diseases, cardiovascular disorder, connective tissue disorder, diffuse scleroderma, hypertensive disorder, interstitial lung disease, lung disorder, pulmonary hypertension, respiratory system disorder, skin disorder, systemic sclerosis, vascular disorder | Recruiting | Phase 2 | 2026-08-14 | NCT03630211 |