systemic sclerosis
systemic sclerosis
Explore linked clinical trials. Standard reference: MONDO:0005100234 results · Page 1 of 10
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| A Phase 1/2 Study of PRO-203 in Healthy Volunteers and Participants With Systemic Sclerosis. | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, scleroderma, skin disorder, systemic sclerosis | Recruiting | Phase 1 / Phase 2 | 2026-10-09 | NCT07641634 | |
| The Effect of Progressive Muscle Relaxation Exercises on Fatigue, Dyspnea, and Respiratory Function in Patients With Systemic Sclerosis | Dyspnea, Fatigue, Pathological Conditions, Signs and Symptoms, Respiration Disorders, Signs and Symptoms, Signs and Symptoms, Respiratory, Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, respiratory system disorder, skin disorder, systemic sclerosis | Recruiting | Not applicable | 2026-10-08 | NCT07842133 | |
| Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders | Bronchiolitis Obliterans, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Skin and Connective Tissue Diseases, Urogenital Diseases, autoimmune disease, bronchial disorder, bronchiolitis, bronchiolitis obliterans syndrome, bronchitis, connective tissue disorder, cryptogenic organizing pneumonia, glomerulonephritis, graft versus host disease, immune system disorder, kidney disorder, lung disorder, lupus nephritis, nephritis, obstructive lung disease, respiratory system disorder, skin disorder, systemic lupus erythematosus, systemic sclerosis, urinary system disorder | Recruiting | Phase 1 / Phase 2 | 2026-10-06 | NCT06434363 | |
| Using AI-Assisted Cameras to Track Hand Exercises in Scleroderma Patients | Skin and Connective Tissue Diseases, connective tissue disorder, skin disorder, systemic sclerosis | Not yet recruiting | Not applicable | 2026-10-05 | NCT07858838 | |
| EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc) | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, skin disorder, systemic sclerosis | Recruiting | Phase 2 | 2026-10-05 | NCT07287670 | |
| Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO | CNS demyelinating autoimmune disease, Crohn disease, Digestive System Diseases, Hemic and Lymphatic Diseases, Neoplasms by Site, Sjogren syndrome, Skin Diseases, Papulosquamous, Skin and Connective Tissue Diseases, Spondylarthritis, Spondylarthropathies, Stomatognathic Diseases, Xerostomia, arthritic joint disease, arthropathy, autoimmune disease, autoimmune disorder of the nervous system, bone disorder, colitis, colonic disorder, connective tissue disorder, demyelinating disease, dermatomyositis, digestive system disorder, dry eye syndrome, eye disorder, gastroenteritis, hematologic disorder, hematopoietic and lymphoid cell neoplasm, hematopoietic and lymphoid system neoplasm, immune system disorder, inflammatory bowel disease, intestinal disorder, lacrimal apparatus disorder, mouth disorder, multiple sclerosis, muscle tissue disorder, musculoskeletal system disorder, myositis disease, neoplasm, nervous system disorder, neuromuscular disease, polymyositis, psoriasis, psoriatic arthritis, rheumatic disorder, rheumatoid arthritis, salivary gland disorder, skin disorder, spondylitis, systemic lupus erythematosus, systemic sclerosis, ulcerative colitis, vertebral column disorder | Recruiting | Phase 1 | 2026-10-05 | NCT03816345 | |
| A Phase 1b Study of C-CAR168 in Participants With Systemic Sclerosis (SSc) | Skin and Connective Tissue Diseases, autoimmune disease, connective tissue disorder, diffuse scleroderma, immune system disorder, skin disorder, systemic sclerosis | Not yet recruiting | Phase 1 | 2026-10-02 | NCT07854483 | |
| A Study to Learn About a Medicine Called PF-08154225 in Participants With Autoimmune Diseases | Skin and Connective Tissue Diseases, acquired idiopathic inflammatory myopathy, arthritic joint disease, arthropathy, autoimmune disease, connective tissue disorder, immune system disorder, muscle tissue disorder, musculoskeletal system disorder, myositis disease, nervous system disorder, neuromuscular disease, rheumatic disorder, rheumatoid arthritis, skin disorder, systemic lupus erythematosus, systemic sclerosis | Not yet recruiting | Phase 1 / Phase 2 | 2026-10-01 | NCT07782450 | |
| Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, digital ulcers, skin disorder, systemic sclerosis | Recruiting | Phase 2 | 2026-10-01 | NCT06954597 | |
| Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, skin disorder, systemic sclerosis | Recruiting | Phase 2 | 2026-10-01 | NCT04986605 | |
| Comparative Autoantibody and Immunologic Cell Marker Study | AIDS, Blood-Borne Infections, Chronic Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cytopenia, DNA Virus Infections, Digestive System Diseases, Disease Attributes, Epstein-Barr virus infection, Flaviviridae infectious disease, Genital Diseases, Guillain-Barre syndrome, HIV infectious disease, Hemic and Lymphatic Diseases, Hemorrhage, Herpesviridae infectious disease, Immunoglobulin G4-Related Disease, Infections, Inflammation, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Post-Infectious Disorders, Purpura, Thrombocytopenic, Idiopathic, RNA Virus Infections, Sepsis, Signs and Symptoms, Sjogren syndrome, Skin Manifestations, Skin and Connective Tissue Diseases, Slow Virus Diseases, Stomatognathic Diseases, Systemic Inflammatory Response Syndrome, Tumor Virus Infections, Undifferentiated Connective Tissue Diseases, Urogenital Diseases, Xerostomia, arthritic joint disease, arthropathy, autoimmune disease, autoimmune disorder of the nervous system, autoimmune lymphoproliferative syndrome, blood coagulation disease, blood platelet disease, connective tissue disorder, demyelinating disease, diffuse scleroderma, dry eye syndrome, eye disorder, graft versus host disease, hematologic disorder, hemorrhagic disease, hepatitis, hepatitis C virus infection, hereditary disease, immune system disorder, immunoproliferative disorder, inborn error of immunity, infectious disease, juvenile idiopathic arthritis, lacrimal apparatus disorder, lentivirus infection, liver disorder, lymphatic system disorder, lymphoproliferative syndrome, mouth disorder, muscle tissue disorder, musculoskeletal system disorder, myositis disease, nervous system disorder, neuromuscular disease, peripheral nervous system disorder, polyneuropathy, polyradiculoneuropathy, purpura, rheumatic disorder, rheumatoid arthritis, salivary gland disorder, sexually transmitted disease, skin disorder, systemic lupus erythematosus, systemic sclerosis, thrombocytopenia, thrombocytopenic purpura, thrombotic microangiopathy, uterine carcinosarcoma, viral hepatitis, viral infectious disease, viral sexually transmitted disease | Enrolling by invitation | Not stated | 2026-10-01 | NCT02422875 | |
| A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, skin disorder, systemic sclerosis | Recruiting | Phase 3 | 2026-09-30 | NCT07497087 | |
| Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY) | Skin and Connective Tissue Diseases, autoimmune disease, connective tissue disorder, diffuse scleroderma, immune system disorder, interstitial lung disease, lung disorder, respiratory system disorder, scleroderma, skin disorder, systemic sclerosis | Active, not recruiting | Phase 3 | 2026-09-30 | NCT05925803 | |
| Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung Disease | Skin and Connective Tissue Diseases, connective tissue disorder, interstitial lung disease, lung disorder, respiratory system disorder, skin disorder, systemic sclerosis | Recruiting | Phase 2 | 2026-09-29 | NCT05785065 | |
| A Study of KITE-363 in Participants With Refractory Autoimmune Diseases | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Skin and Connective Tissue Diseases, Urogenital Diseases, autoimmune disease, connective tissue disorder, glomerulonephritis, immune system disorder, kidney disorder, lupus nephritis, muscle tissue disorder, musculoskeletal system disorder, myositis disease, nephritis, nervous system disorder, neuromuscular disease, skin disorder, systemic lupus erythematosus, systemic sclerosis, urinary system disorder | Enrolling by invitation | Phase 1 | 2026-09-28 | NCT07038447 | |
| A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, skin disorder, systemic sclerosis | Recruiting | Phase 2 | 2026-09-28 | NCT06470048 | |
| Sildenafil for Early Pulmonary Vascular Disease in Scleroderma | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, scleroderma, skin disorder, systemic sclerosis | Recruiting | Phase 2 | 2026-09-28 | NCT04797286 | |
| Obinutuzumab in Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, skin disorder, systemic sclerosis | Not yet recruiting | Phase 2 | 2026-09-25 | NCT07842523 | |
| Home-based Exercise for Improving Health-related Quality of Life in Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, diffuse scleroderma, skin disorder, systemic sclerosis | Not yet recruiting | Not applicable | 2026-09-25 | NCT07840430 | |
| Combined Growth Differentiation Factor-15 (GDF-15) and Lung Ultrasound for ILD Screening in Rheumatoid Arthritis and Systemic Sclerosis | Fibrosis, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, arthritic joint disease, arthropathy, autoimmune disease, connective tissue disorder, immune system disorder, interstitial lung disease, lung disorder, musculoskeletal system disorder, pulmonary fibrosis, respiratory system disorder, rheumatic disorder, rheumatoid arthritis, skin disorder, systemic sclerosis | Not yet recruiting | Not stated | 2026-09-25 | NCT07839221 | |
| Investigation of Type I Interferon Excess in Patients With Systemic Autoimmune Diseases and Genetic Type I Interferonopathies | Skin and Connective Tissue Diseases, connective tissue disorder, muscle tissue disorder, musculoskeletal system disorder, myositis disease, nervous system disorder, neuromuscular disease, skin disorder, systemic sclerosis | Not yet recruiting | Not applicable | 2026-09-24 | NCT07837986 | |
| A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, skin disorder, systemic sclerosis | Recruiting | Phase 2 | 2026-09-24 | NCT06655155 | |
| Clinical Cohort Study of Systemic Sclerosis | Skin and Connective Tissue Diseases, connective tissue disorder, skin disorder, systemic sclerosis | Recruiting | Not stated | 2026-09-23 | NCT07836361 | |
| Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseases | Sjogren syndrome, Skin and Connective Tissue Diseases, Stomatognathic Diseases, Xerostomia, anti-neutrophil cytoplasmic antibody-associated vasculitis, antiphospholipid syndrome, arthritic joint disease, arthropathy, autoimmune disease, cardiovascular disorder, connective tissue disorder, dry eye syndrome, eye disorder, immune system disorder, lacrimal apparatus disorder, mouth disorder, musculoskeletal system disorder, necrotizing vasculitis, rheumatic disorder, rheumatoid arthritis, salivary gland disorder, skin disorder, skin vascular disease, systemic lupus erythematosus, systemic sclerosis, vascular disorder, vasculitis | Recruiting | Early phase 1 | 2026-09-23 | NCT07301164 | |
| Safety and Efficacy of Universal CAR-T Cells (UWD-CD19) Combined With Immunosuppressants in the Treatment of Refractory Autoimmune Diseases | Sjogren syndrome, Skin and Connective Tissue Diseases, Stomatognathic Diseases, Xerostomia, anti-neutrophil cytoplasmic antibody-associated vasculitis, arthritic joint disease, arthropathy, autoimmune disease, cardiovascular disorder, connective tissue disorder, dry eye syndrome, eye disorder, immune system disorder, lacrimal apparatus disorder, mouth disorder, muscle tissue disorder, musculoskeletal system disorder, myositis disease, necrotizing vasculitis, nervous system disorder, neuromuscular disease, rheumatic disorder, rheumatoid arthritis, salivary gland disorder, skin disorder, skin vascular disease, systemic sclerosis, vascular disorder, vasculitis | Not yet recruiting | Phase 1 / Phase 2 | 2026-09-23 | NCT06821659 |