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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial DysfunctionChandler syndrome, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Corneal Endothelial Cell Loss, Corneal Endothelial Dystrophy 1, Eye Diseases, Hereditary, Eye Manifestations, Fuchs' endothelial dystrophy, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Signs and Symptoms, congenital hereditary endothelial dystrophy of cornea, corneal disorder, corneal dystrophy, corneal edema, eye disorder, hereditary diseaseRecruitingPhase 22026-10-09NCT07729137
A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal EctasiaCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Dilatation, Pathologic, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, corneal disorder, corneal dystrophy, eye disorder, hereditary disease, keratoconusRecruitingNot stated2026-10-08NCT02118922
DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingPhase 22026-09-28NCT07024693
The Belgian Endothelial Surgical Transplant of the CorneaCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, bullous keratopathy, corneal disorder, corneal dystrophy, corneal edema, eye disorder, hereditary diseaseActive, not recruitingNot applicable2026-09-14NCT05436665
The Effect of Topical Rho-kinase Inhibitors on Corneas of Patients With Fuchs Endothelial Corneal DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, cataract, corneal disorder, corneal dystrophy, corneal edema, eye disorder, glaucoma, hereditary disease, lens disorder, ocular hypertensionEnrolling by invitationNot stated2026-09-09NCT06969586
Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingPhase 22026-09-02NCT04440280
Partial Range Of Field IOLs in DMEK-Enabled ProceduresCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, cataract, corneal disorder, corneal dystrophy, eye disorder, hereditary disease, lens disorderNot yet recruitingNot applicable2026-08-25NCT07441616
Descemet Endothelial Thickness Comparison Trial IICongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingPhase 32026-08-17NCT05275972
Postoperative CCT in FECD vs. Non-FECDCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, cataract, corneal disorder, corneal dystrophy, eye disorder, hereditary disease, lens disorderNot yet recruitingNot stated2026-08-10NCT07731945
Prognosis of Posterior Lamellar KeratoplastyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot stated2026-06-24NCT06859411
Effect of Descemet Membrane Polishing in Fuchs Endothelial Corneal DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot applicable2026-05-26NCT07539012
Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in FranceCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Corneal Dystrophy, Posterior Polymorphous, 1, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot stated2026-05-06NCT05742321
Plasma Rich in Growth Factors in Corneal Endothelial TransplantationCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, corneal edema, eye disorder, hereditary diseaseRecruitingNot applicable2026-04-09NCT06261346
Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 YearsCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseEnrolling by invitationNot applicable2026-02-27NCT07217249
Influence of Supine Positioning on the Outcomes After Descemet Membrane Endothelial Keratoplasty (DMEK)Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot applicable2026-01-28NCT07373821
PVEK Corneal Implant For Treatment of Corneal EdemaCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, corneal edema, eye disorder, hereditary diseaseRecruitingPhase 12026-01-12NCT07325097
Study to Assess Safety and Tolerability of Multiple Doses of EO2002Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Corneal Dystrophy, Posterior Polymorphous, 1, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, bullous keratopathy, corneal disorder, corneal dystrophy, corneal edema, corneal endothelial dystrophy, eye disorder, hereditary diseaseRecruitingPhase 12025-12-08NCT05636579
SUCCESS Score Validation in Fuchs DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot stated2025-12-04NCT07265388
The OPTIMISE StudyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingPhase 42025-10-06NCT05716945
Safety and Efficacy of Tissue Engineered Endothelial KeratoplastyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, bullous keratopathy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingPhase 12025-09-12NCT04319848
OCT in Fuchs' DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot stated2025-09-09NCT04258787
Comparison of Outcomes Between Femtosecond Laser-Assisted and Conventional Phacoemulsification in Fuchs Endothelial Corneal Dystrophy Patients With CataractsCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, cataract, corneal disorder, corneal dystrophy, eye disorder, hereditary disease, lens disorderRecruitingNot stated2025-06-17NCT06966167
Brillouin Microscopy Used to Evaluate Corneal Mechanical PropertiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, epithelial basement membrane dystrophy, eye disorder, hereditary diseaseNot yet recruitingNot applicable2025-04-06NCT06914817
FECD-TRACE: Fuchs' Endothelial Corneal Dystrophy TRAjectory and Correlation With Genotype in the United KingdomCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Corneal Dystrophy, Posterior Polymorphous, 1, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot stated2025-03-18NCT06881771
Trial Comparing Cataract Surgery With Triple-DMEK in Patients With Cataract and Fuchs Endothelial Corneal DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, cataract, corneal disorder, corneal dystrophy, eye disorder, hereditary disease, lens disorderRecruitingNot applicable2025-02-21NCT06425666