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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
MHB018A Treatment in Patients With Active Thyroid Eye DiseaseCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Graves Ophthalmopathy, Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hereditary disease, hyperthyroidism, immune system disorder, thyroid gland disorderActive, not recruitingPhase 32026-10-09NCT06989918
Transconjunctival Versus Transcutaneous Betamethasone for Upper Eyelid Retraction in TEDCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Graves Ophthalmopathy, Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hereditary disease, hyperthyroidism, immune system disorder, thyroid gland disorderNot yet recruitingNot applicable2026-10-08NCT07866261
A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years OldGraves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingPhase 22026-10-07NCT07722546
Thyroid-Stimulating Hormone Receptor (TSHR) Blockade With REGN24493 in Adult Participants With Graves' Disease (GD)Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorderNot yet recruitingPhase 12026-10-06NCT07861152
Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' DiseaseGraves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingPhase 32026-10-06NCT07661056
AI-Based Wearable Monitoring (Glandy HYPER) for Antithyroid Drug Dose Adjustment in Graves' DiseaseGraves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorder, thyrotoxicosisNot yet recruitingNot applicable2026-10-05NCT07857421
Evaluation of YB-101 for Safety, Tolerability, Pharmacokinetics, and Efficacy in Graves' DiseaseGraves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingPhase 22026-10-05NCT07682896
Prospective Evaluation of OptiThyDoseBone Diseases, Developmental, Bone Diseases, Endocrine, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dwarfism, Graves disease, autoimmune disease, bone disorder, congenital hypothyroidism, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hereditary disease, hyperthyroidism, hypothyroidism, immune system disorder, musculoskeletal system disorder, thyroid gland disorderRecruitingNot applicable2026-10-02NCT06864351
A Study to Investigate the Efficacy and Safety of Rilzabrutinib in Adult Participants With Graves' DiseaseGraves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingPhase 22026-10-01NCT06984627
NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' DiseaseGraves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingPhase 12026-09-30NCT07305818
A Long-Term Extension Study of IMVT-1402 in Adult Participants With Graves' Disease (GD)Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorderEnrolling by invitationPhase 22026-09-29NCT07286006
A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease.Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingPhase 32026-09-24NCT07596849
A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' DiseaseGraves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingPhase 32026-09-24NCT07570316
MHB018A Treatment in Patients With Chronic Thyroid Eye DiseaseCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Graves Ophthalmopathy, Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hereditary disease, hyperthyroidism, immune system disorder, thyroid gland disorderActive, not recruitingPhase 32026-09-24NCT07257185
Comparative Evaluation of 68Ga-FAPI and 68Ga-DOTATATE PET/CT and PET/MRI in Thyroid Eye DiseaseCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Graves Ophthalmopathy, Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hereditary disease, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingNot stated2026-09-23NCT07835607
Thyroid Disorders in Pediatric Autoimmune HepatitisDigestive System Diseases, Graves disease, Hashimoto thyroiditis, Hepatitis, Chronic, autoimmune disease, autoimmune hepatitis, autoimmune thyroid disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hepatitis, hyperthyroidism, immune system disorder, liver disorder, thyroid gland disorder, thyroiditisNot yet recruitingNot stated2026-09-22NCT07827235
An Open-Label Trial of Veligrotug in Participants With Thyroid Eye Disease Who Previously Responded to TeprotumumabCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Graves Ophthalmopathy, Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hereditary disease, hyperthyroidism, immune system disorder, thyroid gland disorderNot yet recruitingPhase 42026-09-21NCT07832136
Early Risk Stratification of Thyroid Eye Disease in Newly Diagnosed Graves' DiseaseCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Graves Ophthalmopathy, Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hereditary disease, hyperthyroidism, immune system disorder, thyroid gland disorderNot yet recruitingNot stated2026-09-10NCT07812194
Validating Immunological Markers Associated With Mental Fatigue in Graves' DiseaseFatigue, Graves disease, Mental Fatigue, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingNot stated2026-09-10NCT06081439
A Study to Assess the Efficacy and Safety of ZL-1109 in Chinese Participants With Active Thyroid Eye DiseaseCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Graves Ophthalmopathy, Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hereditary disease, hyperthyroidism, immune system disorder, thyroid gland disorderActive, not recruitingPhase 32026-09-09NCT07211776
A Trial Investigating Lu AG22515 in Adult Participants With Moderate-to-Severe Thyroid Eye DiseaseCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Graves Ophthalmopathy, Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hereditary disease, hyperthyroidism, immune system disorder, thyroid gland disorderActive, not recruitingPhase 12026-09-09NCT06557850
A Clinical Study of Cizutamig in Thyroid Eye DiseaseCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Graves Ophthalmopathy, Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hereditary disease, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingPhase 12026-09-01NCT07597200
A Study of VV-14305 for the Treatment of Thyroid Eye DiseaseCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Graves Ophthalmopathy, Graves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hereditary disease, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingPhase 1 / Phase 22026-08-27NCT07404111
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' DiseaseGraves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingPhase 22026-08-25NCT07018323
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' DiseaseGraves disease, autoimmune disease, disease of orbital part of eye adnexa, endocrine system disorder, exophthalmos, eye disorder, goiter, hyperthyroidism, immune system disorder, thyroid gland disorderRecruitingPhase 22026-08-25NCT06727604