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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Study to Assess the Safety and Immunogenicity of TPOXX® When Administered Orally for 28 Days With JYNNEOSDNA Virus Infections, Infections, milker's nodule, smallpox, viral infectious diseaseActive, not recruitingPhase 22026-09-14NCT04957485
Evaluation of Effectiveness and Safety of LC16m8 Mpox Vaccine in the Democratic Republic of Congo (DRC)DNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseRecruitingNot stated2026-08-31NCT07093489
New York City Observational Study of Mpox ImmunityDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseEnrolling by invitationNot stated2026-08-27NCT05654883
Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)Adnexal Diseases, DNA Virus Infections, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Infections, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, endocrine system disorder, fallopian tube cancer, fallopian tube disorder, fallopian tube neoplasm, female reproductive system disorder, female reproductive system neoplasm, gonadal disorder, malignant endocrine neoplasm, milker's nodule, neoplasm, ovarian cancer, ovarian disorder, primary peritoneal carcinoma, vaccinia, viral infectious diseaseRecruitingPhase 32026-08-26NCT05281471
Smart Analysis and Decision-Making for Emerging Infectious DiseasesAlphavirus infectious disease, COVID-19, Communicable Diseases, Emerging, Coronaviridae Infections, DNA Virus Infections, Disease Attributes, Flaviviridae infectious disease, Flavivirus Infections, Infections, Mosquito-Borne Diseases, Nidovirales infectious disease, Orthocoronavirinae infectious disease, Pathologic Processes, Pathological Conditions, Signs and Symptoms, RNA Virus Infections, Togaviridae infectious disease, arbovirus infection, avian influenza, bird disease, chikungunya, dengue disease, infectious disease, influenza, lung disorder, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, pneumonia, respiratory system disorder, respiratory tract infectious disorder, rodent disease, vector-borne disease, viral hemorrhagic fever, viral infectious disease, viral pneumoniaEnrolling by invitationNot applicable2026-08-19NCT07678619
Smallpox Vaccine for Mpox Post-Exposure Prophylaxis: A Cluster RCTDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseActive, not recruitingPhase 42026-08-12NCT05745987
A Randomized Clinical Trial Investigating the Safety, Reactogenicity, and Immunogenicity After Immunization With an mRNA-based Mpox Vaccine Candidate in AfricaDNA Virus Infections, Infections, Orthopoxvirus Infection, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, smallpox, viral infectious diseaseRecruitingPhase 22026-08-11NCT07379580
IDOV-Immune for Advanced Solid TumorsAdnexal Diseases, Cancer of the Uterine Cervix, DNA Virus Infections, Digestive System Diseases, Digestive System Neoplasms, Esophageal Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Head and Neck Neoplasms, Infections, Liver Neoplasms, Male Urogenital Diseases, Neoplasm Metastasis, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, Thoracic Neoplasms, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, adenocarcinoma, adrenal gland cancer, adrenal gland disorder, benign urinary system neoplasm, breast cancer, breast disorder, breast neoplasm, carcinoma, cervix disorder, colonic disorder, colorectal cancer, colorectal neoplasm, digestive system disorder, digestive system neoplasm, endocrine system disorder, epithelial neoplasm, esophageal cancer, esophageal disorder, female reproductive system disorder, female reproductive system neoplasm, gastric cancer, gastric neoplasm, gonadal disorder, hepatocellular carcinoma, intestinal disorder, kidney cancer, kidney disorder, liver disorder, lung cancer, lung disorder, lung neoplasm, male reproductive organ cancer, male reproductive system disorder, malignant endocrine neoplasm, malignant pancreatic neoplasm, melanocytic neoplasm, melanoma, milker's nodule, neoplasm, neuroendocrine neoplasm, ovarian cancer, ovarian disorder, pancreas disorder, pancreatic neoplasm, primitive neuroectodermal tumor, prostate cancer, prostate disorder, rectal disorder, renal cell carcinoma, respiratory system disorder, respiratory tract neoplasm, sarcoma, skin disorder, skin neoplasm, stomach disorder, urinary bladder cancer, urinary bladder disorder, urinary bladder neoplasm, urinary system disorder, uterine disorder, vaccinia, viral infectious diseaseRecruitingPhase 12026-08-05NCT06910657
Characterization of Vaccine-induced Responses Against Monkeypox (MoVIHvax) An Observational Prospective Cohort StudyDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseRecruitingNot stated2026-07-07NCT05562323
Validation of SDS-EDTA-Treated Chromatography Paper Strips for Mpox Sampling and Transport in DRCDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseRecruitingNot stated2026-06-11NCT07634081
Mpox Biology, Outcome, Transmission and Epidemiology - Tracking the Immune Response After mpoX vaCcination (MBOTE-TRAXX): Clinical Study to Monitor the Immunological Response Following Mpox Vaccination in the City of Kinshasa, Democratic Republic of the CongoDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseActive, not recruitingPhase 42026-06-11NCT07499739
Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL CancerDNA Virus Infections, Infections, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, carcinoma, epithelial neoplasm, lung disorder, lung neoplasm, milker's nodule, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasm, vaccinia, viral infectious diseaseRecruitingPhase 22026-06-04NCT06463665
Assessment of the Efficacy and Safety of Tecovirimat in Patients With Monkeypox Virus DiseaseDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseActive, not recruitingPhase 32026-05-26NCT05597735
An Immunogenicity and Safety Trial of MVA-BN in Adults Living With HIV for the Prevention of Mpox Infection, in Kinshasa, DRCDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseActive, not recruitingPhase 22026-05-19NCT06839989
Assessment of Immune Memory - Humoral and Cellular - in mPOX-infected Patients : an Ancillary Study of the ANRS0258s MOSAIC CohortDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseNot yet recruitingNot applicable2026-05-18NCT07592429
VA-005 Clinical Outcomes of VIGIV Treatment of Smallpox Vaccination Complications or Vaccinia InfectionDNA Virus Infections, Infections, milker's nodule, smallpox, viral infectious diseaseEnrolling by invitationNot stated2026-05-12NCT01374984
Phase 3 Infant Safety & Immunogenicity Trial of MVA-BN® in DRCDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, smallpox, viral infectious diseaseActive, not recruitingPhase 32026-04-29NCT06844487
Understanding MPXV Viral Clearance, Transmission Dynamics, and Mpox Vaccine Effectiveness in West Africa : GuineaDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseNot yet recruitingNot stated2026-04-16NCT07534267
Comparability Trial of the MVA-BN Vaccine Manufactured in Different Production CellsDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseActive, not recruitingPhase 22026-04-08NCT07199569
Prospective Study for the FOLLOW-UP of Human Monkeypox Cases and Smallpox Vaccinees at RiskDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseRecruitingNot stated2026-03-19NCT05879965
Recombinant Human IL-21-expressing Oncolytic Vaccinia Virus Injection (hV01) in Advanced Pancreatic CancerDNA Virus Infections, Digestive System Diseases, Digestive System Neoplasms, Infections, Neoplasms by Site, endocrine system disorder, malignant endocrine neoplasm, milker's nodule, neoplasm, pancreas disorder, pancreatic neoplasm, vaccinia, viral infectious diseaseRecruitingPhase 22026-02-27NCT07006077
Phase 3 Maternal Safety & Immunogenicity Trial of MVA-BN® in DRCDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, smallpox, viral infectious diseaseActive, not recruitingPhase 32026-01-30NCT06844500
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BSY001 After Single/Multiple Doses.DNA Virus Infections, Infections, cowpox, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, smallpox, viral infectious diseaseRecruitingPhase 12026-01-29NCT07377175
Prospective Follow-up After MVA-BN Booster VaccinationDNA Virus Infections, Infections, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, rodent disease, viral infectious diseaseNot yet recruitingNot stated2026-01-20NCT07342829
Neutralizing Power of Serum Antibodies - 2COVID-19, Coronaviridae Infections, DNA Virus Infections, Infections, Nidovirales infectious disease, Orthocoronavirinae infectious disease, RNA Virus Infections, lung disorder, milker's nodule, monkeypox, non-human animal disease, non-human primate disease, pneumonia, respiratory system disorder, respiratory tract infectious disorder, rodent disease, viral infectious disease, viral pneumoniaRecruitingNot applicable2025-12-19NCT07085611