fibrolamellar hepatocellular carcinoma
fibrolamellar hepatocellular carcinoma
Explore linked clinical trials. Standard reference: MONDO:000621012 results · Page 1 of 1
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC) | Digestive System Diseases, Digestive System Neoplasms, Liver Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, carcinoma, epithelial neoplasm, fibrolamellar hepatocellular carcinoma, liver disorder, neoplasm | Recruiting | Phase 1 | 2026-10-05 | NCT07430202 | |
| Peptide Vaccine for Fibrolamellar Hepatocellular Carcinoma Patients and Other Tumor Entities Carrying the Driver Fusion DNAJB1-PRKACA | fibrolamellar hepatocellular carcinoma | Recruiting | Phase 1 | 2026-09-14 | NCT06789198 | |
| Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery | Neoplasms by Histologic Type, fibrolamellar hepatocellular carcinoma, hepatoblastoma, mixed neoplasm, neoplasm, pediatric hepatocellular carcinoma | Active, not recruiting | Phase 3 | 2026-09-14 | NCT03533582 | |
| Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients | Digestive System Diseases, Digestive System Neoplasms, Liver Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, adenocarcinoma, carcinoma, childhood malignant neoplasm, epithelial neoplasm, fibrolamellar hepatocellular carcinoma, hepatocellular carcinoma, liver disorder, neoplasm | Recruiting | Phase 1 / Phase 2 | 2026-05-19 | NCT05468359 | |
| Agnostic Therapy in Rare Solid Tumors | Adnexal Diseases, Biliary Tract Neoplasms, Carcinoma, Ovarian Epithelial, DNA Virus Infections, Digestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Head and Neck Neoplasms, Herpesviridae infectious disease, Infections, Kaposi's sarcoma, MIT family translocation renal cell carcinoma, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Bone Tissue, Neoplasms, Connective and Soft Tissue, Neoplasms, Fibrous Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Parathyroid Neoplasms, Pregnancy Complications, Neoplastic, Sertoli-Leydig cell tumor, Sex Cord-Gonadal Stromal Tumors, Urogenital Diseases, Urogenital Neoplasms, adenocarcinoma, adenoid cystic carcinoma, adenoma, adrenal gland cancer, adrenal gland disorder, angiosarcoma, anus disorder, anus neoplasm, apocrine adenocarcinoma, benign urinary system neoplasm, biliary tract disorder, bladder urachal adenocarcinoma, bladder urachal carcinoma, breast secretory carcinoma, capillary hemangioma, carcinoma, carcinosarcoma, cholangiocarcinoma, colorectal neoplasm, connective tissue neoplasm, digestive system disorder, digestive system neoplasm, endocrine system disorder, epithelial neoplasm, fallopian tube disorder, fallopian tube neoplasm, female reproductive system disorder, female reproductive system neoplasm, fibrolamellar hepatocellular carcinoma, fibrosarcoma, gallbladder disorder, gallbladder neoplasm, gonadal disorder, gonadal tissue neoplasm, granulosa cell tumor, hemangioblastoma, hemangioma, hepatoblastoma, intestinal disorder, leiomyosarcoma, male reproductive organ cancer, male reproductive system disorder, malignant endocrine neoplasm, mesonephric neoplasm, mesothelial neoplasm, mesothelioma, metaplastic breast carcinoma, mixed neoplasm, myomatous neoplasm, neoplasm, nerve sheath neoplasm, nervous system disorder, neuroblastoma, neuroendocrine neoplasm, neuroepithelial neoplasm, neurofibroma, neurofibrosarcoma, neuromuscular disease, osteosarcoma, ovarian cancer, ovarian disorder, parathyroid gland carcinoma, parathyroid gland disorder, penile disorder, penile neoplasm, peripheral nervous system disorder, peripheral nervous system neoplasm, pregnancy disorder, primitive neuroectodermal tumor, rectal disorder, rectal neoplasm, sarcoma, testicular cancer, testicular disorder, thyroid gland disorder, thyroid tumor, trophoblastic neoplasm, urethra neoplasm, urethral disorder, urinary system disorder, vaginal cancer, vaginal disorder, vascular cancer, viral infectious disease, vulva cancer, vulvar disease, yolk sac tumor | Recruiting | Phase 2 | 2026-04-15 | NCT06638931 | |
| Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer | Adnexal Diseases, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Thoracic Neoplasms, Urogenital Diseases, Urogenital Neoplasms, angiosarcoma, bronchial neoplasm, bronchogenic carcinoma, endocrine system disorder, endometrium neoplasm, female reproductive system disorder, female reproductive system neoplasm, fibrolamellar hepatocellular carcinoma, gonadal disorder, lung disorder, lung neoplasm, male reproductive organ cancer, male reproductive system disorder, malignant endocrine neoplasm, neoplasm, non-small cell lung carcinoma, ovarian cancer, ovarian disorder, prostate cancer, prostate disorder, respiratory system disorder, respiratory tract neoplasm, sarcoma, uterine disorder, vascular cancer | Active, not recruiting | Phase 1 | 2026-03-30 | NCT03860272 | |
| Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma | Digestive System Diseases, Digestive System Neoplasms, Liver Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, adenocarcinoma, carcinoma, epithelial neoplasm, fibrolamellar hepatocellular carcinoma, hepatocellular carcinoma, liver cancer, liver disorder, neoplasm | Recruiting | Phase 2 | 2026-02-24 | NCT04134559 | |
| DRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC) | Neoplasms by Histologic Type, carcinoma, epithelial neoplasm, fibrolamellar hepatocellular carcinoma, neoplasm | Recruiting | Phase 1 / Phase 2 | 2026-02-12 | NCT06027086 | |
| DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma | fibrolamellar hepatocellular carcinoma | Recruiting | Phase 1 | 2025-12-03 | NCT04248569 | |
| A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer | Digestive System Diseases, Digestive System Neoplasms, Hemic and Lymphatic Diseases, Hodgkins lymphoma, Liver Neoplasms, Myosarcoma, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Bone Tissue, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, adenocarcinoma, astrocytoma (excluding glioblastoma), brain disorder, brainstem cancer, carcinoma, central nervous system cancer, central nervous system disorder, connective tissue neoplasm, diffuse intrinsic pontine glioma, ependymoma, epithelial neoplasm, fibrolamellar hepatocellular carcinoma, glioblastoma, glioma, hepatoblastoma, hepatocellular carcinoma, immune system disorder, immunoproliferative disorder, liver disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, melanocytic neoplasm, melanoma, mixed neoplasm, myomatous neoplasm, neoplasm, nervous system disorder, neuroendocrine neoplasm, neuroepithelial neoplasm, osteosarcoma, primitive neuroectodermal tumor, rhabdomyosarcoma, sarcoma, skin disorder, skin neoplasm | Active, not recruiting | Phase 1 / Phase 2 | 2025-11-12 | NCT06521567 | |
| A French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers | Digestive System Diseases, Digestive System Neoplasms, Liver Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, adenocarcinoma, carcinoma, cholangiocarcinoma, combined hepatocellular carcinoma and cholangiocarcinoma, epithelial neoplasm, fibrolamellar hepatocellular carcinoma, hepatoblastoma, liver disorder, liver neuroendocrine carcinoma, mixed neoplasm, neoplasm | Recruiting | Not stated | 2025-08-05 | NCT06541652 | |
| FusionVAC22_01: Fusion Transcript-based Peptide Vaccine Combined with Immune Checkpoint Inhibition | fibrolamellar hepatocellular carcinoma | Recruiting | Phase 1 | 2024-12-09 | NCT05937295 |