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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, paranasal sinus disorder, polyp, respiratory system disorderRecruitingPhase 32026-10-09NCT07782957
Metabolic and Immunologic Biomarkers in Chronic Rhinosinusitis With Nasal PolypsPathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderRecruitingNot stated2026-10-06NCT07860411
FESS With or Without Intranasal Desmopressin in Chronic Rhinosinusitis With Nasal PolypsPathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, chronic rhinosinusitis, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderNot yet recruitingNot applicable2026-10-06NCT07855315
Biologics in Chronic Rhinosinusitis With Nasal PolyposisInfections, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, chronic rhinosinusitis, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, paranasal sinus disorder, polyp, respiratory system disorder, respiratory tract infectious disorder, sinusitisRecruitingPhase 42026-09-28NCT06824649
Efficacy and Safety of Depemokimab Monotherapy Without Concomitant Use of Intranasal Corticosteroids (INCS) in Japanese Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderRecruitingPhase 42026-09-08NCT07701967
China CRSwNP Registry StudyPathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderNot yet recruitingNot stated2026-08-31NCT07795658
A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, paranasal sinus disorder, polyp, respiratory system disorderNot yet recruitingPhase 32026-08-24NCT07782970
Active vs. Passive VR During Office-based ENT ProceduresAirway Obstruction, Nasal Obstruction, Neurologic Manifestations, Pain, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Respiration Disorders, Signs and Symptoms, anxiety, anxiety disorder, laryngeal disorder, nasal cavity polyp, nasal disorder, nervous system disorder, otorhinolaryngologic disease, polyp, psychiatric disorder, respiratory failure, respiratory system disorder, spasmodic dystonia, voice disordersNot yet recruitingNot applicable2026-08-17NCT07599826
Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory DiseaseAsthma, Aspirin-Induced, Chemically-Induced Disorders, Drug-Related Side Effects and Adverse Reactions, Hypersensitivity, Immediate, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Respiratory Hypersensitivity, asthma, bronchial disorder, drug allergy, immune system disorder, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderActive, not recruitingPhase 22026-08-13NCT05575037
Triamcinolone Nanocapsules After Endoscopic Nasal SurgeryPathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderRecruitingPhase 22026-07-27NCT07714525
Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell TrainingNeurologic Manifestations, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, anosmia, nasal cavity polyp, nasal disorder, nervous system disorder, otorhinolaryngologic disease, polyp, respiratory system disorderRecruitingNot applicable2026-07-02NCT07681973
Preoperative Stapokibart for Endoscopic Sinus Surgery in Chronic Rhinosinusitis With Nasal PolypsPathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderNot yet recruitingNot applicable2026-06-01NCT07616609
BIOlogics in Severe Nasal POlyposis SurvEy.: a French RegistryPathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderRecruitingNot applicable2026-05-18NCT06501807
Polysomnographic Findings in Nasal PolyposisApnea, Dyssomnias, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Respiration Disorders, Sleep Disorders, Intrinsic, nasal cavity polyp, nasal disorder, nervous system disorder, obstructive sleep apnea syndrome, otorhinolaryngologic disease, polyp, respiratory system disorder, sleep apnea syndrome, sleep-wake disorderRecruitingNot applicable2026-05-06NCT03725956
Xylitol vs Saline Nasal Irrigations in CF-CRSCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Infant, Newborn, Diseases, Pathologic Processes, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, cystic fibrosis, disease, hereditary disease, lung disorder, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, pancreas disorder, polyp, respiratory system disorderEnrolling by invitationNot applicable2026-05-01NCT05531630
BIOlogics in Severe Nasal POlyposis SurvEyPathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderActive, not recruitingNot stated2026-04-29NCT05228041
Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic AsthmaEosinophilia, Hemic and Lymphatic Diseases, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, hematologic disorder, hypereosinophilic syndrome, leukocyte disorder, lung disorder, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, pulmonary eosinophilia, respiratory system disorderActive, not recruitingNot stated2026-04-17NCT06069310
Inflammatory Profiles, Histopathological Features, and Remodeling Factors in Chronic Rhinosinusitis With Nasal PolypsPathologic Processes, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, disease, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderNot yet recruitingNot applicable2026-04-14NCT07528820
Phenotyping of Type 2 Inflammation Profile by Rheology of Nasal Secretions and Tissue Quantification of Eosinophilic Polymorphonuclear Cells in the Middle TurbinatePathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderNot yet recruitingNot applicable2026-04-13NCT07524127
Follow-up of Spanish Prospective Asthma and Nasal Polyposis RegistryHypersensitivity, Immediate, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Respiratory Hypersensitivity, asthma, bronchial disorder, chronic asthma, immune system disorder, lung disorder, nasal cavity polyp, nasal disorder, obstructive lung disease, otorhinolaryngologic disease, polyp, respiratory system disorderRecruitingNot stated2026-03-30NCT06163807
In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal PolypsInfections, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, paranasal sinus disorder, polyp, respiratory system disorder, respiratory tract infectious disorder, sinusitisRecruitingNot applicable2025-12-30NCT02975310
Pilot Study of The EPIC TrialInfections, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, paranasal sinus disorder, polyp, respiratory system disorder, respiratory tract infectious disorder, sinusitisActive, not recruitingNot applicable2025-12-30NCT02533206
Complete Remission After Treatment With Biologics for Nasal PolypsPathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderRecruitingPhase 42025-12-05NCT07268313
A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal PolypsInfections, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, paranasal sinus disorder, polyp, respiratory system disorder, respiratory tract infectious disorder, sinusitisActive, not recruitingPhase 32025-12-03NCT06639295
Effect of Full-House ESS With Nasopharyngeal Lymphoid Tissue Ablation on Nasal PolypsPathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, nasal cavity polyp, nasal disorder, otorhinolaryngologic disease, polyp, respiratory system disorderRecruitingNot applicable2025-11-24NCT07245329