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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
PRESTO: A Phase III Randomised Controlled Trial of Dose-escalated Proton Beam Therapy Versus Standard of Care Radiotherapy for Functioning Pituitary TumoursACTH-dependent Cushing syndrome, Bone Diseases, Endocrine, Growth Hormone-Secreting Pituitary Adenoma, Neoplasms by Histologic Type, Neoplasms by Site, Pituitary Neoplasms, acromegaly, adenoma, bone disorder, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, epithelial neoplasm, hyperpituitarism, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, musculoskeletal system disorder, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerNot yet recruitingPhase 32026-10-01NCT07813351
Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical ProceduresEar Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Otorhinolaryngologic Neoplasms, Pituitary Neoplasms, acoustic neuroma, astrocytoma (excluding glioblastoma), brain cancer, brain disorder, central nervous system cancer, central nervous system disorder, cranial nerve neoplasm, cranial nerve neuropathy, endocrine system disorder, epithelial neoplasm, glioblastoma, glioma, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, meningioma, neoplasm, nerve sheath neoplasm, nervous system disorder, neuroendocrine neoplasm, neuroepithelial neoplasm, neuroma, otorhinolaryngologic disease, peripheral nervous system neoplasm, pituitary gland adenoma, pituitary gland disorder, primitive neuroectodermal tumor, retrocochlear disease, schwannoma, supratentorial cancer, tumor of meninges, vascular cancer, vestibulocochlear nerve disorderRecruitingEarly phase 12026-06-30NCT07493447
Clinical Trial of an Anti-Fog Drainage Device for Endoscopic Endonasal Sellar Region Tumor SurgeryNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, craniopharyngioma, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, primitive neuroectodermal tumor, supratentorial cancerRecruitingNot applicable2026-06-30NCT07316101
FET PET/CT Imaging To Localize Pituitary Adenomas In Cushing DiseaseACTH-dependent Cushing syndrome, Neoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerRecruitingEarly phase 12026-06-22NCT07460232
Standardized Patient Education in Pituitary SurgeryNeoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerNot yet recruitingNot applicable2026-06-01NCT07618949
Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region.Head and Neck Neoplasms, Lewy body dementia, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Nutritional and Metabolic Diseases, Parathyroid Neoplasms, Parkinson disease, Pituitary Neoplasms, TDP-43 proteinopathy, amyotrophic lateral sclerosis, basal ganglia disorder, brain cancer, brain disorder, central nervous system cancer, central nervous system disorder, cognitive disorder, dementia, endocrine system disorder, epilepsy, epithelial neoplasm, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, metabolic disease, motor neuron disorder, movement disorder, neoplasm, nervous system disorder, neuroblastoma, neurodegenerative disease, neuroepithelial neoplasm, neuromuscular disease, parathyroid gland adenoma, parathyroid gland disorder, parkinsonian disorder, pituitary gland adenoma, pituitary gland disorder, primitive neuroectodermal tumor, proteostasis deficiencies, psychiatric disorder, spinal cord disorder, supratentorial cancer, synucleinopathyEnrolling by invitationNot applicable2026-05-19NCT07595666
DOTATOC PET/CT for Imaging NET PatientsAdenoma, Islet Cell, Carcinoma, Medullary, DNA Virus Infections, Digestive System Diseases, Digestive System Neoplasms, Infections, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Ductal, Lobular, and Medullary, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Pituitary Neoplasms, Thoracic Neoplasms, Tumor Virus Infections, VIPoma, adenocarcinoma, adenoma, brain disorder, bronchial neoplasm, bronchogenic carcinoma, carcinoid tumor, carcinoma, central nervous system cancer, central nervous system disorder, cutaneous neuroendocrine carcinoma, endocrine system disorder, epithelial neoplasm, glioma, glucagonoma, hypothalamic disorder, hypothalamic neoplasm, lung disorder, lung neoplasm, malignant endocrine neoplasm, medulloblastoma, meningioma, neoplasm, nervous system disorder, neuroblastoma, neuroendocrine carcinoma, neuroendocrine neoplasm, neuroepithelial neoplasm, pancreas disorder, pancreatic endocrine carcinoma, pancreatic insulinoma, pancreatic neoplasm, paraganglioma, pheochromocytoma, pituitary gland adenoma, pituitary gland disorder, polyomavirus infectious disease, primitive neuroectodermal tumor, respiratory system disorder, respiratory tract neoplasm, small cell lung carcinoma, supratentorial cancer, tumor of meninges, vascular cancer, viral infectious diseaseActive, not recruitingNot stated2026-05-12NCT03583528
AI in Endoscopic Transsphenoidal SurgeryNeoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerNot yet recruitingEarly phase 12026-05-05NCT07568366
A First in Human Study Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers for Malignant Brain TumorsNeoplasms by Site, Pituitary Neoplasms, brain cancer, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerActive, not recruitingPhase 12026-05-01NCT03465618
DDAVP for Pituitary AdenomaACTH-dependent Cushing syndrome, Neoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerRecruitingNot applicable2026-04-09NCT04569591
Use of [18F] Fluoroethyl-L-tyrosine PET/MRI for Identifying Small Functional Pituitary AdenomasNeoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerRecruitingPhase 12026-03-09NCT07456878
Prediction Model for Postoperative Headache After Transsphenoidal Pituitary SurgeryHeadache, Neoplasms by Site, Neurologic Manifestations, Pain, Pathological Conditions, Signs and Symptoms, Pituitary Neoplasms, Signs and Symptoms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerActive, not recruitingNot stated2026-03-03NCT07446036
Hypofractionated Proton Therapy for Benign Intracranial Brain Tumors, the HiPPI StudyNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Intracranial, Neoplasms, Nerve Tissue, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, grade II meningioma, grade III meningioma, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, meningioma, neoplasm, nerve sheath neoplasm, nervous system disorder, neuroendocrine neoplasm, neuroma, neuromuscular disease, peripheral nervous system disorder, peripheral nervous system neoplasm, pituitary gland adenoma, pituitary gland disorder, primitive neuroectodermal tumor, schwannoma, supratentorial cancer, tumor of meninges, vascular cancerRecruitingNot applicable2026-02-17NCT04278118
Evaluation of Intraoperative Contrast Enhanced Ultrasound for the Identification of Pituitary Adenoma in Cushing's Disease Compared to Other Pituitary TumorsACTH-dependent Cushing syndrome, Neoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerRecruitingNot stated2026-01-13NCT07335315
Molecular Pituitary Imaging Using 18F-FET PETNeoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerRecruitingNot applicable2026-01-06NCT06584123
68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.Esthesioneuroblastoma, Olfactory, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Pituitary Neoplasms, brain disorder, capillary hemangioma, central nervous system cancer, central nervous system disorder, cranial nerve neuropathy, endocrine system disorder, epithelial neoplasm, glioma, hemangioblastoma, hemangioma, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, medulloblastoma, meningioma, neoplasm, nervous system disorder, neuroblastoma, neuroendocrine neoplasm, neuroepithelial neoplasm, olfactory nerve disorder, paraganglioma, pituitary gland adenoma, pituitary gland disorder, primitive neuroectodermal tumor, supratentorial cancer, tumor of meninges, vascular cancerRecruitingPhase 42025-11-21NCT04081701
Proton Versus Photon Radiotherapy in Adults With Primary Brain TumorsBrain Tumor, Primary, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, meningioma, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancer, tumor of meninges, vascular cancerRecruitingNot applicable2025-09-16NCT06831461
Cabergoline in the Management of Nonfunctioning Pituitary AdenomaNeoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerEnrolling by invitationPhase 42025-06-24NCT07034859
A Twenty-years' Experience in Pituitary Disease.Neoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerRecruitingNot stated2025-05-15NCT06973824
The Impact of Endoscopic Endonasal Skull Base Surgery on OlfactionNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, craniopharyngioma, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, meningioma, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, primitive neuroectodermal tumor, supratentorial cancer, tumor of meninges, vascular cancerRecruitingNot stated2025-04-23NCT06874426
Hydrocortisone in Hormone Replacement Therapy for Large Pituitary Neuroendocrine TumorsNeoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerRecruitingPhase 42025-01-14NCT06679816
Osilodrostat Therapy and 11C-methionine PET to Improve Corticotroph Adenoma DetectionACTH-dependent Cushing syndrome, ACTH-producing pituitary gland adenoma, Cushing disease due to pituitary adenoma, Cushing syndrome, Neoplasms by Histologic Type, Neoplasms by Site, Pituitary Neoplasms, adenoma, adrenal gland disorder, adrenal gland hyperfunction, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, epithelial neoplasm, hyperpituitarism, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerNot yet recruitingNot stated2024-12-03NCT06701838
SeOuL cOhort of Brain Tumor MONitoring Study (SOLOMON)Brain Tumor, Primary, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, meningioma, neoplasm, nerve sheath neoplasm, nervous system disorder, neuroendocrine neoplasm, neuroma, pituitary gland adenoma, pituitary gland disorder, primitive neuroectodermal tumor, schwannoma, supratentorial cancer, tumor of meninges, vascular cancerRecruitingNot stated2024-12-03NCT05254197
Pre-operative Surgical Difficulty Stratification Using Predicted Tumor Perfusion and ConsistencyNeoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerActive, not recruitingNot stated2024-10-29NCT06664190
Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical ModelsBody Weight, Bone Diseases, Endocrine, Cushing syndrome, Neoplasms by Site, Nutritional and Metabolic Diseases, Overweight, Pathological Conditions, Signs and Symptoms, Pituitary Neoplasms, Signs and Symptoms, acromegaly, adrenal gland disorder, adrenal gland hyperfunction, bone disorder, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypopituitarism, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, musculoskeletal system disorder, neoplasm, nervous system disorder, nutritional disorder, obesity disorder, overnutrition, pituitary gland adenoma, pituitary gland disorder, supratentorial cancerNot yet recruitingNot stated2024-06-11NCT06326853