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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Mirdametinib in Histiocytic DisordersHemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, Skin and Connective Tissue Diseases, histiocytosis, interstitial lung disease, juvenile xanthogranuloma, lung disorder, lymphatic system disorder, non-Langerhans cell histiocytosis, respiratory system disorder, sinus histiocytosis with massive lymphadenopathy, skin disorderRecruitingPhase 22026-09-21NCT06153173
Histiocytic Disorder Follow-up StudyErdheim-Chester disease, Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, Histiocytosis, Malignant, Neoplasms by Histologic Type, Neoplasms, Second Primary, histiocytic sarcoma, histiocytosis, interstitial lung disease, lung disorder, lymphatic system disorder, malignant histiocytosis, neoplasm, non-Langerhans cell histiocytosis, respiratory system disorder, sinus histiocytosis with massive lymphadenopathy, xanthogranulomaRecruitingNot stated2026-06-12NCT05915208
In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PETBlood Protein Disorders, Erdheim-Chester disease, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, cardiovascular disorder, hematologic disorder, hemorrhagic disease, histiocytosis, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, monoclonal gammopathy, neoplasm, non-Hodgkin lymphoma, non-Langerhans cell histiocytosis, plasma cell neoplasm, sinus histiocytosis with massive lymphadenopathy, vascular disorder, vascular hemostatic diseaseRecruitingEarly phase 12026-02-05NCT05093335
Registry for Patients With Erdheim-Chester Disease and Other HistiocytosesErdheim-Chester disease, Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, histiocytosis, interstitial lung disease, lung disorder, lymphatic system disorder, non-Langerhans cell histiocytosis, respiratory system disorder, sinus histiocytosis with massive lymphadenopathyRecruitingNot stated2026-01-08NCT03329274
Efficacy and Safety of the RD Regimen(Lenalidomide, Dexamethasone) for Rosai-Dorfman DiseaseHemic and Lymphatic Diseases, histiocytosis, lymphatic system disorder, non-Langerhans cell histiocytosis, sinus histiocytosis with massive lymphadenopathyRecruitingPhase 22025-09-22NCT07187167
Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic DisordersErdheim-Chester disease, Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, Neoplasms by Histologic Type, Skin and Connective Tissue Diseases, histiocytic sarcoma, histiocytosis, interstitial lung disease, juvenile xanthogranuloma, lung disorder, lymphatic system disorder, malignant histiocytosis, neoplasm, non-Langerhans cell histiocytosis, respiratory system disorder, sinus histiocytosis with massive lymphadenopathy, skin disorderRecruitingPhase 22025-09-18NCT04079179
International Rare Histiocytic Disorders Registry (IRHDR)Collagen Diseases, Erdheim-Chester disease, Granuloma, Hemic and Lymphatic Diseases, Lipid Metabolism Disorders, Necrobiotic Disorders, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, connective tissue disorder, histiocytosis, lymphatic system disorder, lymphoproliferative syndrome, metabolic disease, necrobiotic xanthogranuloma, non-Langerhans cell histiocytosis, sinus histiocytosis with massive lymphadenopathy, skin disorder, xanthomatosisRecruitingNot stated2025-06-24NCT02285582