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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including MesotheliomaAdnexal Diseases, Digestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, Urogenital Diseases, Urogenital Neoplasms, adenoma, colonic disorder, colonic neoplasm, colorectal neoplasm, digestive system disorder, digestive system neoplasm, endocrine system disorder, epithelial neoplasm, female reproductive system disorder, female reproductive system neoplasm, gastric neoplasm, gonadal disorder, intestinal disorder, lung disorder, lung neoplasm, lymphatic system disorder, malignant endocrine neoplasm, mesothelial neoplasm, mesothelioma, mixed neoplasm, neoplasm, ovarian cancer, ovarian disorder, pancreas disorder, pancreatic neoplasm, respiratory system disorder, respiratory tract neoplasm, stomach disorder, thymomaRecruitingPhase 12026-10-06NCT06885697
A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based ChemotherapyHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, autosomal dominant Parkinson disease 4, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaActive, not recruitingPhase 22026-10-02NCT03076554
Tissue Procurement and Natural History Study of Patients With Malignant MesotheliomaAdnexal Diseases, Biliary Tract Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, Urogenital Diseases, Urogenital Neoplasms, adenoma, biliary tract disorder, digestive system disorder, digestive system neoplasm, endocrine system disorder, epithelial neoplasm, female reproductive system disorder, female reproductive system neoplasm, gastric neoplasm, gonadal disorder, lung disorder, lung neoplasm, lymphatic system disorder, malignant endocrine neoplasm, mesothelial neoplasm, mesothelioma, mixed neoplasm, neoplasm, ovarian cancer, ovarian disorder, pancreas disorder, pancreatic neoplasm, respiratory system disorder, respiratory tract neoplasm, stomach disorder, thymomaRecruitingNot stated2026-10-02NCT01950572
Incidence and Predictors of Early Clinical Relapse Within Six Months After Thymectomy in Patients With Myasthenia GravisDisease Attributes, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Paraneoplastic Syndromes, Nervous System, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, Thoracic Neoplasms, Thymus Neoplasms, autoimmune disease, autoimmune disorder of the nervous system, immune system disorder, lymphatic system disorder, mixed neoplasm, myasthenia gravis, neoplasm, nervous system disorder, neurodegenerative disease, neuromuscular disease, neuromuscular junction disease, paraneoplastic syndrome, thymomaNot yet recruitingNot stated2026-10-01NCT07853378
An Investigational Scan (MRI) in Imaging Patients With Newly-Diagnosed or Recurrent ThymomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaActive, not recruitingNot applicable2026-09-18NCT03968315
HEARTS Trial for Thoracic CancersDigestive System Diseases, Digestive System Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, bronchial neoplasm, bronchogenic carcinoma, digestive system disorder, digestive system neoplasm, esophageal disorder, lung disorder, lung neoplasm, lymphatic system disorder, mixed neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasm, thymomaRecruitingPhase 22026-09-15NCT07132918
SP Thoracic IDE StudyHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Paraneoplastic Syndromes, Nervous System, Thoracic Neoplasms, Thymus Neoplasms, autoimmune disease, autoimmune disorder of the nervous system, immune system disorder, lymphatic system disorder, mixed neoplasm, myasthenia gravis, neoplasm, nervous system disorder, neurodegenerative disease, neuromuscular disease, neuromuscular junction disease, paraneoplastic syndrome, thymomaActive, not recruitingNot applicable2026-09-14NCT05150210
A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial TumorsHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaRecruitingPhase 22026-09-11NCT06248515
PT-112 in Subjects With Thymoma and Thymic CarcinomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, nervous system disorder, neuromuscular disease, peripheral nervous system disorder, thymic epithelial neoplasm, thymoma, thymus cancerRecruitingPhase 22026-08-28NCT05104736
Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic CarcinomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymic epithelial neoplasm, thymoma, thymus cancerActive, not recruitingPhase 22026-08-28NCT04417660
Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic CarcinomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaRecruitingPhase 22026-08-12NCT07324629
A Phase II, Investigator-Initiated Exploratory Study of Sacituzumab Tirumotecan for Previously Treated Unresectable Thymic CarcinomasHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaNot yet recruitingPhase 22026-08-06NCT07750353
Pembrolizumab and Sunitinib Malate in Treating Participants With Refractory Metastatic or Unresectable Thymic CancerHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaActive, not recruitingPhase 22026-08-06NCT03463460
Chemotherapy Plus Cetuximab Followed by Surgical Resection in Patients With Locally Advanced or Recurrent Thymoma or Thymic CarcinomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaActive, not recruitingPhase 22026-07-29NCT01025089
Hypofractionated Adjuvant Radiotherapy for Thymic Epithelial TumorsHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymic epithelial neoplasm, thymomaNot yet recruitingNot applicable2026-07-16NCT07693855
Pembrolizumab in Treating Participants With Unresectable Thymoma or Thymic CancerHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaRecruitingPhase 12026-07-16NCT03295227
IMMUNORARE5: A National Platform of 5 Academic Phase II Trials Coordinated by Lyon University Hospital to Assess the Safety and the Efficacy of the IMMUNOtherapy With Domvanalimab + Zimberelimab Combination in Patients With Advanced RARE CancersFemale Urogenital Diseases and Pregnancy Complications, Gestational Trophoblastic Disease, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Pregnancy Complications, Neoplastic, Thoracic Neoplasms, Thymus Neoplasms, Urogenital Diseases, adenocarcinoma, carcinoid tumor, carcinoma, digestive system neuroendocrine neoplasm, epithelial neoplasm, gestational trophoblastic neoplasm, lymphatic system disorder, mixed neoplasm, neoplasm, neuroendocrine neoplasm, peritoneal mesothelioma, pregnancy disorder, primitive neuroectodermal tumor, thymoma, thyroid gland undifferentiated (anaplastic) carcinoma, trophoblastic neoplasmActive, not recruitingPhase 22026-06-25NCT06790706
Target-Selected CAR-NK Cells (CD30, CD5, or Mesothelin) for Relapsed/Refractory B2 Thymoma or Thymic CarcinomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymic epithelial neoplasm, thymomaRecruitingPhase 1 / Phase 22026-05-20NCT07598955
Nivolumab in Patients With Type B3 Thymoma and Thymic Carcinoma (NIVOTHYM)Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymoma, thymoma type B3Active, not recruitingPhase 22026-05-15NCT03134118
Neoadjuvant Treatment For Locally Advanced Thymic CancerHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaRecruitingPhase 22026-05-08NCT06019468
Thymic Disease, Autoimmunity, and Neuromuscular Junction Integrity in Myasthenia GravisHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Paraneoplastic Syndromes, Nervous System, Thoracic Neoplasms, Thymus Neoplasms, autoimmune disease, autoimmune disorder of the nervous system, immune system disorder, lymphatic system disorder, mixed neoplasm, myasthenia gravis, neoplasm, nervous system disorder, neurodegenerative disease, neuromuscular disease, neuromuscular junction disease, paraneoplastic syndrome, thymomaNot yet recruitingNot stated2026-05-06NCT07571525
Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaRecruitingPhase 32026-04-27NCT06402708
Adjuvant Radiotherapy for Stage II/III Thymoma After Complete ResectionHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaRecruitingNot applicable2026-04-24NCT02633553
Neoadjuvant Adebrelimab Plus CRT for Locally Advanced Thymic CarcinomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaNot yet recruitingPhase 22026-03-18NCT07479628
6 vs 3 Cycles of Neoadjuvant Chemotherapy for Potentially Resectable Locally Advanced Thymic Epithelial TumorsHemic and Lymphatic Diseases, Mediastinal Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Diseases, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mediastinal cancer, mixed neoplasm, neoplasm, respiratory system disorder, thymic epithelial neoplasm, thymomaNot yet recruitingPhase 2 / Phase 32026-03-11NCT07463313