rheumatic heart disease
rheumatic heart disease
Explore linked clinical trials. Standard reference: MONDO:000695521 results · Page 1 of 1
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| ACT4RHD is an Open-label, Randomised, Adaptive Platform Trial to Evaluate Novel and Repurposed Clinical Interventions for Patients With Acute Rheumatic Fever and Carditis. ACT4RHD Seeks to Determine Whether These Interventions Reduce RHD Severity at 6 Months. | Bacterial Infections and Mycoses, Infections, Skin and Connective Tissue Diseases, arthritic joint disease, arthropathy, bacterial infectious disease, cardiovascular disorder, connective tissue disorder, gram-positive bacterial infections, heart disorder, musculoskeletal system disorder, rheumatic disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Not yet recruiting | Phase 3 | 2026-10-07 | NCT07830108 | |
| Treating Severe Mitral Valve Annular or Valvular Calcification Using Shockwave Balloon SMARTWAVE | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, heart valve disorder, mitral valve stenosis, rheumatic fever, rheumatic heart disease, streptococcal infection | Recruiting | Not applicable | 2026-09-16 | NCT06952374 | |
| Penicillin to Prevent Early Rheumatic Heart Disease in School-Aged Children | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Not yet recruiting | Phase 3 | 2026-09-03 | NCT07798232 | |
| Multi-country Evaluation of Early RHD in Children Across Africa for Vaccine Trial Readiness | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Not yet recruiting | Not stated | 2026-08-27 | NCT07790302 | |
| Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System | Bacterial Infections and Mycoses, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Hemic and Lymphatic Diseases, Infections, Male Urogenital Diseases, Nutritional and Metabolic Diseases, Urogenital Diseases, anemia, bacterial infectious disease, brain disorder, cancer, cardiovascular disorder, central nervous system disorder, congenital heart disease, diabetes mellitus, endocrine system disorder, epilepsy, familial hemolytic anemia, glucose metabolism disease, gram-positive bacterial infections, heart disorder, heart failure, hematologic disorder, hemolytic anemia, hereditary disease, hypertensive disorder, inherited hemoglobinopathy, kidney disorder, metabolic disease, neoplasm, nervous system disorder, rheumatic fever, rheumatic heart disease, sickle cell disease, streptococcal infection, urinary system disorder, vascular disorder | Recruiting | Not stated | 2026-08-07 | NCT07753681 | |
| Testing a Registry-Based Strategy (ACT+) to Reduce Loss to Follow-Up in Rheumatic Heart Disease Screening in Uganda | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Not yet recruiting | Not applicable | 2026-07-13 | NCT07606131 | |
| A Non-Inferiority Trial of Stopping Penicillin in Early Rheumatic Heart Disease: GOAL-Stop | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Recruiting | Phase 3 | 2026-06-22 | NCT07146048 | |
| GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD Trial | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Active, not recruiting | Phase 2 | 2026-06-22 | NCT05693545 | |
| Artificial Intelligence to Scale Early Rheumatic Heart Disease Detection | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Not yet recruiting | Not applicable | 2026-05-27 | NCT07599956 | |
| Accelerating Delivery of rheUmatic Heart Disease Preventive iNterventions in Northern Uganda | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Recruiting | Not applicable | 2026-05-15 | NCT05783375 | |
| School-based Program for the Prevention of Rheumatic Heart Disease in Endemic Regions | Bacterial Infections and Mycoses, Infections, Skin and Connective Tissue Diseases, arthritic joint disease, arthropathy, bacterial infectious disease, cardiovascular disorder, connective tissue disorder, gram-positive bacterial infections, heart disorder, heart valve disorder, musculoskeletal system disorder, rheumatic disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Recruiting | Not applicable | 2026-01-20 | NCT06720272 | |
| Echocardiographic Screening of Pregnant Women During Antenatal Care | Bacterial Infections and Mycoses, Female Urogenital Diseases and Pregnancy Complications, Infections, Urogenital Diseases, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, heart valve disorder, pregnancy disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Active, not recruiting | Not applicable | 2026-01-20 | NCT04936815 | |
| Vitamin K Antagonist in Rheumatic Heart Disease Patients With Mechanical Heart Valves: Our Current Status | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Not yet recruiting | Not stated | 2025-08-28 | NCT07146282 | |
| Clinical Trial Phase I/IIa to Evaluate the Safety and Immunogenicity of StreptInCor | Bacterial Infections and Mycoses, Infections, Skin and Connective Tissue Diseases, arthritic joint disease, arthropathy, bacterial infectious disease, cardiovascular disorder, connective tissue disorder, gram-positive bacterial infections, heart disorder, musculoskeletal system disorder, rheumatic disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Not yet recruiting | Phase 1 / Phase 2 | 2025-07-22 | NCT07078357 | |
| Korea VHD Echo Study: Surveillance of Aortic, Mitral & Tricuspid Patients - Insights From Real-world Practice | Bacterial Infections and Mycoses, Heart Valve Prolapse, Infections, Ventricular Outflow Obstruction, aortic disorder, aortic valve disorder, aortic valve insufficiency, aortic valve stenosis, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, heart valve disorder, mitral valve insufficiency, mitral valve prolapse, rheumatic fever, rheumatic heart disease, streptococcal infection, tricuspid valve insufficiency, vascular disorder | Not yet recruiting | Not stated | 2025-07-16 | NCT07068633 | |
| Effectiveness of Edutainment-Based Interventions in Increasing Knowledge of Rheumatic Fever and Rheumatic Heart Disease Among School-Going Children in Nepal: Study Protocol for Colors to Save Hearts Quasi-Experimental Pretest-Posttest Study | Bacterial Infections and Mycoses, Infections, Skin and Connective Tissue Diseases, arthritic joint disease, arthropathy, bacterial infectious disease, cardiovascular disorder, connective tissue disorder, gram-positive bacterial infections, heart disorder, musculoskeletal system disorder, rheumatic disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Not yet recruiting | Not applicable | 2025-07-15 | NCT07065474 | |
| The Clinical Influence of Developing a Sustainable Cardiac Surgery Service to Reduce the Burden of Rheumatic Heart Disease in Sub-Saharan Africa | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Recruiting | Not stated | 2025-06-12 | NCT04556188 | |
| Screening and Secondary Prevention Rheumatic Heart Disease Study | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Recruiting | Not stated | 2023-08-15 | NCT05991219 | |
| Rheumatic Heart Disease Research and Screening in Nepal: A Feasibility Study | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Active, not recruiting | Not stated | 2023-06-05 | NCT05250154 | |
| Role of Statins In Slowing Rheumatic Heart Disease (RHD) Progression | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Active, not recruiting | Not stated | 2023-06-05 | NCT04575857 | |
| Effectiveness of a School-centered Prevention Program on Prevalence of Latent Rheumatic Heart Disease | Bacterial Infections and Mycoses, Infections, bacterial infectious disease, cardiovascular disorder, gram-positive bacterial infections, heart disorder, rheumatic fever, rheumatic heart disease, streptococcal infection | Recruiting | Not applicable | 2022-08-17 | NCT05504928 |