Gerstmann-Straussler-Scheinker syndrome

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Trial	Conditions	Status	Phase	Updated	More info	NCT ID
A Trial of ALN-6457 in Adult Participants With Symptomatic Prion Disease (PrD)	Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Creutzfeldt Jacob disease, Dyssomnias, Gerstmann-Straussler-Scheinker syndrome, Infections, Nutritional and Metabolic Diseases, Sleep Disorders, Intrinsic, brain disorder, central nervous system disorder, central nervous system infectious disorder, cognitive disorder, dementia, fatal familial insomnia, hereditary disease, inherited neurodegenerative disorder, insomnia, metabolic disease, nervous system disorder, neurodegenerative disease, prion disease, proteostasis deficiencies, psychiatric disorder, sleep-wake disorder	Not yet recruiting	Phase 1 / Phase 2	2026-09-22		NCT07832370
PrP-targeting siRNA Safety & Mechanism Study	Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Creutzfeldt Jacob disease, Dyssomnias, Gerstmann-Straussler-Scheinker syndrome, Infections, Sleep Disorders, Intrinsic, brain disorder, central nervous system disorder, central nervous system infectious disorder, cognitive disorder, dementia, fatal familial insomnia, hereditary disease, inherited neurodegenerative disorder, insomnia, nervous system disorder, neurodegenerative disease, prion disease, psychiatric disorder, sleep-wake disorder	Recruiting	Phase 1	2026-08-28		NCT07444580

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