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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Open-Label Access to ATH434 for Patients Who Completed Study ATH434-201 in Franceautonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathyEnrolling by invitationPhase 22026-10-09NCT07729852
An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophyautonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathyRecruitingPhase 22026-10-09NCT07197866
A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophyautonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathyActive, not recruitingPhase 22026-10-09NCT06568237
Tributyrin for Progressive Supranuclear Palsy (PSP): Virtual TrialNeurologic Manifestations, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cranial nerve neuropathy, eye disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, synucleinopathy, tauopathyRecruitingPhase 1 / Phase 22026-10-07NCT07863180
A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophyautonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathyActive, not recruitingPhase 22026-10-06NCT05923866
VisMemoPD Protocol: an Observational Pilot Study on Spatial and Topographical Memory in Patients With Parkinson's Disease and ParkinsonismCognition Disorders, Cognitive Dysfunction, Mild Cognitive Impairment, Neurologic Manifestations, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, cranial nerve neuropathy, eye disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, progressive supranuclear palsy, psychiatric disorder, synucleinopathy, tauopathyNot yet recruitingNot stated2026-09-18NCT07827963
Neurodegenerative Diseases RegistryNeurologic Manifestations, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cranial nerve neuropathy, eye disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, progressive supranuclear palsy, synucleinopathy, tauopathyRecruitingNot stated2026-09-18NCT04472130
A Trial of ONO-2808 in Participants With the Parkinsonian Subtype of Multiple System Atrophy (MSA-P)Parkinson disease, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, parkinsonian disorder, primary dysautonomia, synucleinopathyNot yet recruitingPhase 32026-09-17NCT07825402
The Study of Safety and Preliminary Efficacy of ALT001 in Patients With MultIple System Atrophy-Cerebellar Typeautonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathyRecruitingEarly phase 12026-09-09NCT07514923
Expansion Study of ALT001 in Patients With Multiple System Atrophyautonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathyRecruitingEarly phase 12026-09-09NCT07476352
Multi-Center Study of Natural History in Atypical Parkinsonian Syndromes (MAPS-NH)Lewy body dementia, Neurologic Manifestations, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, corticobasal degeneration disorder, cranial nerve neuropathy, dementia, eye disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, psychiatric disorder, synucleinopathy, tauopathyRecruitingNot stated2026-09-08NCT07805967
Neurodegenerative Diseases Progression Markers (MARKERS-NDD)Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Frontotemporal Lobar Degeneration, Lewy body dementia, Neurologic Manifestations, Nutritional and Metabolic Diseases, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, amyotrophic lateral sclerosis, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, corticobasal degeneration disorder, cranial nerve neuropathy, dementia, eye disorder, hereditary disease, inherited neurodegenerative disorder, iron metabolism disease, iron poisoning, metabolic disease, motor neuron disorder, movement disorder, multiple system atrophy, nervous system disorder, neuroaxonal dystrophy, neurodegeneration with brain iron accumulation, neurodegenerative disease, neuromuscular disease, ophthalmoplegia, palsy, pantothenate kinase-associated neurodegeneration, parkinsonian disorder, primary dysautonomia, proteostasis deficiencies, psychiatric disorder, spinal cord disorder, synucleinopathy, tauopathyRecruitingNot stated2026-09-02NCT06596746
A Study to Evaluate Satety, Tolerability, Biodistribution, Radiation Dosimetry, and Pharmacokinetics of SST001 in Healthy Volunteers, Patients With PD and Patients With MSAParkinson disease, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, parkinsonian disorder, primary dysautonomia, synucleinopathyRecruitingPhase 12026-09-01NCT07604116
Autologous suraL nervE Grafting to the Substantia nigrA in Patients With SynuclienopathiesNutritional and Metabolic Diseases, Parkinson disease, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, metabolic disease, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, parkinsonian disorder, primary dysautonomia, proteostasis deficiencies, synucleinopathyRecruitingPhase 12026-08-31NCT06683365
Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body DiseaseLewy body dementia, Parkinson disease, Pathologic Processes, Pathological Conditions, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, cardiovascular disorder, central nervous system disorder, cognitive disorder, dementia, disease, familial cylindromatosis, hypotensive disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, parkinsonian disorder, primary dysautonomia, psychiatric disorder, synucleinopathy, vascular disorderActive, not recruitingNot stated2026-08-28NCT06846658
A Prospective Exploratory Study of the Safety and Preliminary Efficacy of the α-Syn H21 Monoclonal Antibody in Patients With Multiple System Atrophyautonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathyNot yet recruitingPhase 12026-08-19NCT07774585
A Phase 2 Study of YA-101 in Patients With Multiple System Atrophyautonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathyActive, not recruitingPhase 22026-08-19NCT06848231
Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register StudyAlzheimer disease, Arterial Occlusive Diseases, Cognition Disorders, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyskinesias, Frontotemporal Lobar Degeneration, Huntington disease, Leukoencephalopathies, Lewy body dementia, Neurologic Manifestations, Nutritional and Metabolic Diseases, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, amyotrophic lateral sclerosis, arteriosclerosis disorder, autonomic nervous system disorder, basal ganglia disorder, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, choreatic disease, cognitive disorder, corticobasal degeneration disorder, cranial nerve neuropathy, dementia, eye disorder, frontotemporal dementia, hereditary disease, inherited neurodegenerative disorder, intracranial arterial disease, intracranial arteriosclerosis, metabolic disease, motor neuron disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, neuromuscular disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, progressive supranuclear palsy, proteostasis deficiencies, psychiatric disorder, spinal cord disorder, synucleinopathy, tauopathy, vascular dementia, vascular disorderActive, not recruitingNot stated2026-08-10NCT06209515
Test-retest Trial With [11C]MODAG-005 in PD or MSA and AMHC - Pilot PhaseNerve Degeneration, Parkinson disease, Pathologic Processes, Pathological Conditions, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, cardiovascular disorder, central nervous system disorder, hypotensive disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, parkinsonian disorder, primary dysautonomia, synucleinopathy, vascular disorderRecruitingEarly phase 12026-07-31NCT07640542
Automated Imaging Differentiation of ParkinsonismNeurologic Manifestations, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cranial nerve neuropathy, eye disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, progressive supranuclear palsy, synucleinopathy, tauopathyActive, not recruitingNot stated2026-07-31NCT05913687
Remote Monitoring in Progressive Supranuclear Palsy (PSP)Neurologic Manifestations, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, cardiovascular disorder, central nervous system disorder, cranial nerve neuropathy, eye disorder, hypotensive disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, progressive supranuclear palsy, synucleinopathy, tauopathy, vascular disorderNot yet recruitingNot stated2026-07-29NCT04753320
A Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA)autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathyActive, not recruitingPhase 32026-07-14NCT06706622
Gait Analysis in Neurological DiseaseAtypical Parkinson Disease, Cognition Disorders, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyskinesias, Gait Disorders, Neurologic, Gait, Frontal, Huntington disease, Neurologic Manifestations, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Spinocerebellar Ataxias, Spinocerebellar Degenerations, atactic disorder, non-human animal, autonomic nervous system disorder, autosomal dominant Parkinson disease 1, basal ganglia disorder, brain disorder, central nervous system disorder, cerebellar ataxia, cerebellar disorder, choreatic disease, cognitive disorder, corticobasal degeneration disorder, cranial nerve neuropathy, dementia, eye disorder, hereditary disease, inherited neurodegenerative disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, progressive supranuclear palsy, psychiatric disorder, spinal cord disorder, synucleinopathy, tauopathyActive, not recruitingNot stated2026-07-08NCT02994719
Epidural Electrical Stimulation to Support Hemodynamic Management in Individuals With Parkinson's DiseaseHypotension, Orthostatic, Multiple system atrophy (MSA) with orthostatic hypotension, Parkinson disease, autonomic nervous system disorder, basal ganglia disorder, brain disorder, cardiovascular disorder, central nervous system disorder, hypotensive disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, orthostatic intolerance, parkinsonian disorder, primary dysautonomia, pure autonomic failure, synucleinopathy, vascular disorderRecruitingNot applicable2026-07-07NCT06920134
Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension SymptomsHypotension, Orthostatic, autonomic nervous system disorder, basal ganglia disorder, brain disorder, cardiovascular disorder, central nervous system disorder, hypotensive disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, orthostatic intolerance, parkinsonian disorder, primary dysautonomia, pure autonomic failure, synucleinopathy, vascular disorderRecruitingNot applicable2026-07-02NCT04782830