Pick disease
Pick disease
Explore linked clinical trials. Standard reference: MONDO:000824331 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of NIO752 in Primary Tauopathies | Frontotemporal Lobar Degeneration, Neurologic Manifestations, Nutritional and Metabolic Diseases, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Pick disease, Signs and Symptoms, TDP-43 proteinopathy, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, corticobasal degeneration disorder, cranial nerve neuropathy, dementia, eye disorder, frontotemporal dementia, metabolic disease, movement disorder, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, progressive supranuclear palsy, proteostasis deficiencies, psychiatric disorder, tauopathy | Not yet recruiting | Phase 2 | 2026-10-09 | NCT07868328 | |
| Restoring Cervical Lymphatic Drainage in Alzheimer's Disease | Alzheimer disease, Frontotemporal Lobar Degeneration, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Pick disease, Plaque, Amyloid, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Not applicable | 2026-10-02 | NCT07854327 | |
| Alzheimer's Disease Neuroimaging Initiative 4 | Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Frontotemporal Lobar Degeneration, Mild Cognitive Impairment, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Pick disease, Plaque, Amyloid, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Enrolling by invitation | Not stated | 2026-09-29 | NCT05617014 | |
| A Dual Orexin Receptor Antagonist to Reduce Biomarkers of Neurodegeneration in Adults With Insomnia. | Dyssomnias, Frontotemporal Lobar Degeneration, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Pick disease, Plaque, Amyloid, Sleep Disorders, Intrinsic, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, insomnia, nervous system disorder, psychiatric disorder, sleep-wake disorder | Recruiting | Phase 2 | 2026-09-18 | NCT06823752 | |
| Alzheimer's Tau Platform: Regimen A - AADvac1 | Alzheimer disease, Frontotemporal Lobar Degeneration, Pick disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Enrolling by invitation | Phase 2 | 2026-09-08 | NCT07167966 | |
| Tau PET/CT in Various Tau-Related Disease Patients | Frontotemporal Lobar Degeneration, Nerve Degeneration, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Pick disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Not stated | 2026-09-08 | NCT06690983 | |
| A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease | Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Frontotemporal Lobar Degeneration, Pick disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Phase 1 | 2026-08-24 | NCT06297590 | |
| Semantic Rehabilitation for Patients With Primary Progressive Semantic Aphasia | Frontotemporal Lobar Degeneration, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Pick disease, Signs and Symptoms, aphasia, brain disorder, central nervous system disorder, cognitive disorder, communication disorder, dementia, frontotemporal dementia, language disorder, nervous system disorder, neurodevelopmental disorder, nominal aphasia, primary progressive aphasia, psychiatric disorder, speech disorder | Recruiting | Not applicable | 2026-08-11 | NCT04957537 | |
| A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy | Frontotemporal Lobar Degeneration, Neurologic Manifestations, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Pick disease, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, cranial nerve neuropathy, dementia, eye disorder, frontotemporal dementia, movement disorder, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, psychiatric disorder, tauopathy | Recruiting | Phase 3 | 2026-07-29 | NCT07498426 | |
| Longitudinal Early-onset Alzheimer's Disease Study Protocol | Alzheimer Disease, Early Onset, Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Frontotemporal Lobar Degeneration, Mild Cognitive Impairment, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Pick disease, Plaque, Amyloid, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Active, not recruiting | Not stated | 2026-07-29 | NCT03507257 | |
| Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study) | Alzheimer disease, Frontotemporal Lobar Degeneration, Pick disease, brain disorder, cardiovascular disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, hypertensive disorder, nervous system disorder, neurodegenerative disease, psychiatric disorder, subjective cognitive decline, tauopathy, vascular disorder | Active, not recruiting | Phase 2 | 2026-07-21 | NCT05331144 | |
| Learning Amyloid and Tau Results | Alzheimer disease, Frontotemporal Lobar Degeneration, Pick disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Enrolling by invitation | Not stated | 2026-06-24 | NCT07222930 | |
| Study of Tau Imaging With the Use of [18F]MK-6240 Tracer | Alzheimer disease, Frontotemporal Lobar Degeneration, Pick disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Enrolling by invitation | Not stated | 2026-06-08 | NCT04104659 | |
| A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes | Frontotemporal Lobar Degeneration, Nutritional and Metabolic Diseases, Pick disease, TDP-43 proteinopathy, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, frontotemporal dementia with motor neuron disease, metabolic disease, nervous system disorder, neurodegenerative disease, proteostasis deficiencies, psychiatric disorder | Active, not recruiting | Phase 1 / Phase 2 | 2026-05-15 | NCT04747431 | |
| Links Between Self-awareness and Sociocognitive Processes in Neurodegenerative Diseases | Alzheimer disease, Frontotemporal Lobar Degeneration, Pick disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Not stated | 2026-04-15 | NCT07531732 | |
| The Swedish BioFINDER 2 Study | Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Frontotemporal Lobar Degeneration, Lewy body dementia, Mild Cognitive Impairment, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Ocular Motility Disorders, Parkinson disease, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Pick disease, Signs and Symptoms, TDP-43 proteinopathy, amyotrophic lateral sclerosis, aphasia, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, communication disorder, corticobasal degeneration disorder, cranial nerve neuropathy, dementia, disease, eye disorder, frontotemporal dementia, language disorder, metabolic disease, motor neuron disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, neuromuscular disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, primary progressive aphasia, progressive non-fluent aphasia, progressive supranuclear palsy, progressive supranuclear palsy-parkinsonism syndrome, proteostasis deficiencies, psychiatric disorder, semantic dementia, speech disorder, spinal cord disorder, synucleinopathy, tauopathy | Recruiting | Not applicable | 2026-04-06 | NCT03174938 | |
| Biology-Driven Cognitive Profiling in Huntington's Disease | Cognition Disorders, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyskinesias, Frontotemporal Lobar Degeneration, Huntington disease, Pick disease, basal ganglia disorder, brain disorder, central nervous system disorder, choreatic disease, cognitive disorder, dementia, frontotemporal dementia, hereditary disease, inherited neurodegenerative disorder, movement disorder, nervous system disorder, neurodegenerative disease, psychiatric disorder | Active, not recruiting | Not stated | 2026-03-31 | NCT07503743 | |
| Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia | Frontotemporal Lobar Degeneration, Nutritional and Metabolic Diseases, Pick disease, TDP-43 proteinopathy, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, metabolic disease, nervous system disorder, neurodegenerative disease, proteostasis deficiencies, psychiatric disorder | Recruiting | Phase 2 | 2026-03-09 | NCT06604520 | |
| Tau PET in Imaging and Cognition: Healthy Adults From 55-90 | Cognition Disorders, Cognitive Dysfunction, Frontotemporal Lobar Degeneration, Mild Cognitive Impairment, Pick disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, psychiatric disorder | Recruiting | Not stated | 2026-02-11 | NCT03372317 | |
| Incremental Diagnostic Value of Tau-PET With [18F]RO948 vs Amyloid-PET in Patients With Cognitive Impairment | Alzheimer disease, Frontotemporal Lobar Degeneration, Pick disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Not applicable | 2025-12-23 | NCT06618872 | |
| Daridorexant for Alzheimer Disease Prevention | Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Frontotemporal Lobar Degeneration, Pick disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy | Recruiting | Phase 2 | 2025-12-19 | NCT07213349 | |
| Understanding Mechanisms of Synaptic Degeneration Underlying Clinical Symptoms in Patients With MDs and NDs. | Alzheimer disease, Bipolar and Related Disorders, Frontotemporal Lobar Degeneration, Pick disease, Schizophrenia Spectrum and Other Psychotic Disorders, bipolar disorder, brain disorder, central nervous system disorder, cognitive disorder, dementia, depressive disorder, frontotemporal dementia, major depressive disorder, mood disorder, nervous system disorder, neurodegenerative disease, psychiatric disorder, schizophrenia, tauopathy | Enrolling by invitation | Not stated | 2025-12-11 | NCT07234851 | |
| Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders | Aphasia, Semantic, Frontotemporal Lobar Degeneration, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Parkinson disease, Pathological Conditions, Signs and Symptoms, Pick disease, Psychomotor Disorders, Signs and Symptoms, TDP-43 proteinopathy, aphasia, apraxia, autonomic nervous system disorder, basal ganglia disorder, behavioral variant of frontotemporal dementia, brain disorder, cardiovascular disorder, central nervous system disorder, cognitive disorder, communication disorder, dementia, frontotemporal dementia, hypotensive disorder, language disorder, logopenic progressive aphasia, metabolic disease, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, parkinsonian disorder, posterior cortical atrophy, primary dysautonomia, primary progressive aphasia, proteostasis deficiencies, psychiatric disorder, semantic dementia, speech disorder, supranuclear palsy, progressive, 1, synucleinopathy, vascular disorder | Enrolling by invitation | Not stated | 2025-11-21 | NCT04680130 | |
| Investigator Initiated Study for the Safety and Efficacy in Frontotemporal Dementia | Frontotemporal Lobar Degeneration, Nutritional and Metabolic Diseases, Pick disease, TDP-43 proteinopathy, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, metabolic disease, nervous system disorder, neurodegenerative disease, proteostasis deficiencies, psychiatric disorder | Not yet recruiting | Phase 2 | 2025-09-04 | NCT07154485 | |
| Tau PET Imaging in the Northern Manhattan Study of Metabolism and Mind. | Frontotemporal Lobar Degeneration, Nutritional and Metabolic Diseases, Pick disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, diabetes mellitus, endocrine system disorder, frontotemporal dementia, glucose intolerance, glucose metabolism disease, hyperglycemia, metabolic disease, nervous system disorder, psychiatric disorder, type 2 diabetes mellitus | Enrolling by invitation | Phase 2 | 2025-05-06 | NCT03389100 |