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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Clinical Genetics Branch Eligibility Screening SurveyAbnormalities, Multiple, Bone Marrow Failure Disorders, Congenital Abnormalities, Congenital Bone Marrow Failure Syndromes, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Costello syndrome, Craniofacial Abnormalities, DNA repair disease, Fanconi anemia, Hemic and Lymphatic Diseases, Infant, Newborn, Diseases, Legius syndrome, Li-Fraumeni syndrome, Musculoskeletal Abnormalities, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Nutritional and Metabolic Diseases, Skin and Connective Tissue Diseases, Thoracic Neoplasms, anemia, aplastic anemia, bone marrow disorder, cardiofaciocutaneous syndrome, chordoma, hematologic disorder, hereditary disease, hereditary neoplastic syndrome, inherited aplastic anemia, lung neoplasm, melanocytic neoplasm, melanoma, metabolic disease, mixed neoplasm, musculoskeletal system disorder, neoplasm, neuroendocrine neoplasm, primitive neuroectodermal tumor, pulmonary blastoma, respiratory tract neoplasm, skin disorder, skin neoplasm, susceptibility to familial cutaneous melanomaNot yet recruitingNot stated2026-10-09NCT07005297
Children and Adults With ChordomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, chordoma, neoplasmRecruitingNot stated2026-10-02NCT03910465
China Treatment Trial for Tumor in Sellar Region With Unruptured Intracranial AneurysmCongenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Rathke Cleft Cysts, brain disorder, central nervous system cancer, central nervous system cyst, central nervous system disorder, central nervous system malformation, chordoma, craniopharyngioma, germinoma, hypothalamic disorder, hypothalamic neoplasm, meningioma, neoplasm, nervous system disorder, optic pathway glioma, primitive neuroectodermal tumor, supratentorial cancer, tumor of meninges, vascular cancerNot yet recruitingNot stated2026-09-09NCT07809178
Cetuximab for the Treatment of Advanced Unresectable or Metastatic ChordomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, chordoma, neoplasmActive, not recruitingPhase 22026-09-04NCT05041127
Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient TumorsNeoplasms by Histologic Type, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, atypical teratoid rhabdoid tumor, chordoma, kidney medullary carcinoma, mixed neoplasm, neoplasm, poorly differentiated chordoma, rhabdoid tumor, sarcomaActive, not recruitingPhase 1 / Phase 22026-07-14NCT05286801
Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative CancersNeoplasms by Histologic Type, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, atypical teratoid rhabdoid tumor, chordoma, mixed neoplasm, neoplasm, rhabdoid tumor, rhabdoid tumor of the kidney, sarcomaActive, not recruitingPhase 22026-07-01NCT04416568
Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid TumorsCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Ewing sarcoma, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Myosarcoma, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Bone Tissue, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Peripheral Nerve Sheath Tumors, Urogenital Diseases, Urogenital Neoplasms, Wilms tumor, alveolar soft part sarcoma, benign urinary system neoplasm, chordoma, clear cell sarcoma, connective tissue neoplasm, desmoplastic small round cell tumor, epithelial neoplasm, hereditary disease, hereditary neoplastic syndrome, kidney cancer, kidney disorder, mixed neoplasm, myoepithelial tumor, myomatous neoplasm, neoplasm, nerve sheath neoplasm, nervous system disorder, neuroblastoma, neuroepithelial neoplasm, neuromuscular disease, osteosarcoma, peripheral nervous system disorder, peripheral nervous system neoplasm, primitive neuroectodermal tumor, rhabdoid tumor, rhabdomyosarcoma, sarcoma, synovial sarcoma, urinary system disorderRecruitingPhase 1 / Phase 22026-06-30NCT06625190
Nivolumab and Ipilimumab in Treating Patients With Rare TumorsAdnexal Diseases, Bartholin gland transitional cell carcinoma, Biliary Tract Neoplasms, Carcinoma, Endometrioid, Cystadenocarcinoma, Serous, Digestive System Diseases, Digestive System Neoplasms, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Gestational Trophoblastic Disease, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Neoplasms, Ductal, Lobular, and Medullary, Neoplasms, Fibrous Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Nose Neoplasms, Otorhinolaryngologic Neoplasms, Parathyroid Neoplasms, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Pharyngeal Diseases, Pregnancy Complications, Neoplastic, Rare Diseases, Stomatognathic Diseases, Thoracic Neoplasms, Urogenital Diseases, Urogenital Neoplasms, acinar cell carcinoma, adenocarcinoma, adenoid cystic carcinoma, adrenal cortex disorder, adrenal cortex neoplasm, adrenal gland cancer, adrenal gland disorder, adrenal gland pheochromocytoma, angiosarcoma, apocrine sweat gland neoplasm, basal cell carcinoma, basal cell neoplasm, bile duct disorder, bile duct neoplasm, biliary tract disorder, bladder adenocarcinoma, carcinoma, carcinosarcoma, cervical adenocarcinoma, cholangiocarcinoma, chordoma, colorectal squamous cell carcinoma, connective tissue neoplasm, cystadenocarcinoma, cystic, mucinous, and serous neoplasm, desmoid tumor, digestive system disorder, digestive system neoplasm, endocrine system disorder, endometrial transitional cell carcinoma, endometrium neoplasm, epithelial neoplasm, extrahepatic bile duct carcinoma, extramammary Paget disease, fallopian tube adenocarcinoma, fallopian tube transitional cell carcinoma, female reproductive system disorder, female reproductive system neoplasm, fibroma, fibromyxoid tumor, fibrosarcoma, gallbladder carcinoma, gallbladder disorder, gallbladder neoplasm, gastric squamous cell carcinoma, gastrointestinal stromal tumor, germinoma, gestational trophoblastic neoplasm, gonadal disorder, intrahepatic cholangiocarcinoma, lung adenocarcinoma, lung giant cell carcinoma, lung neoplasm, lung neuroendocrine neoplasm, lung sarcomatoid carcinoma, major salivary gland carcinoma, malignant endocrine neoplasm, minimally invasive lung adenocarcinoma, mixed neoplasm, mouth disorder, mucinous adenocarcinoma, mucinous adenocarcinoma of the appendix, mucinous cystadenocarcinoma, nasal cavity adenocarcinoma, nasal cavity carcinoma, nasal disorder, nasopharyngeal carcinoma, nasopharyngeal disorder, nasopharyngeal neoplasm, neoplasm, neoplasm with perivascular epithelioid cell differentiation, nerve sheath neoplasm, nervous system disorder, neuroendocrine carcinoma, neuroendocrine neoplasm, neurofibroma, neurofibrosarcoma, neuromuscular disease, oral cavity carcinoma, otorhinolaryngologic disease, ovarian adenocarcinoma, ovarian cancer, ovarian disorder, ovarian germ cell tumor, ovarian mucinous adenocarcinoma, ovarian squamous cell carcinoma, ovarian transitional cell carcinoma, pancreas disorder, pancreatic acinar cell carcinoma, pancreatic endocrine carcinoma, pancreatic neoplasm, paraganglioma, paranasal sinus carcinoma, paranasal sinus disorder, paranasal sinus neoplasm, parathyroid gland carcinoma, parathyroid gland disorder, peripheral nervous system disorder, peripheral nervous system neoplasm, pheochromocytoma, placental choriocarcinoma, pregnancy disorder, primitive neuroectodermal tumor, pseudomyxoma peritonei, respiratory system disorder, respiratory tract neoplasm, sarcoma, scrotum squamous cell carcinoma, seminal vesicle adenocarcinoma, seminoma, small intestine adenocarcinoma, somatostatinoma, spindle cell neoplasm, squamous cell carcinoma of penis, squamous cell carcinoma of the small intestine, testicular non-seminomatous germ cell tumor, thyroid gland carcinoma, thyroid gland disorder, thyroid tumor, trachea carcinoma, transitional cell carcinoma, trophoblastic neoplasm, undifferentiated carcinoma of esophagus, undifferentiated carcinoma of nasopharynx, undifferentiated carcinoma of stomach, ureter adenocarcinoma, ureter squamous cell carcinoma, urethra adenocarcinoma, urethra squamous cell carcinoma, vaginal adenocarcinoma, vascular cancer, vulva cancer, vulvar carcinoma, vulvar diseaseActive, not recruitingPhase 22026-06-17NCT02834013
Proton Beam Therapy for Chordoma PatientsNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, chordoma, neoplasmActive, not recruitingPhase 22026-06-12NCT00496119
Long-Term Longitudinal QoL in Patients Undergoing EEACongenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Esthesioneuroblastoma, Olfactory, Hernia, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Pituitary Neoplasms, Rathke Cleft Cysts, brain disorder, central nervous system cancer, central nervous system cyst, central nervous system disorder, central nervous system malformation, cephalocele, chondrosarcoma, chordoma, connective tissue neoplasm, cranial nerve neuropathy, craniopharyngioma, endocrine system disorder, epithelial neoplasm, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, meningioma, neoplasm, nervous system disorder, neuroblastoma, neuroepithelial neoplasm, olfactory nerve disorder, pituitary gland disorder, primitive neuroectodermal tumor, sarcoma, supratentorial cancer, tumor of meninges, vascular cancerActive, not recruitingNot stated2026-05-20NCT04087902
A Study of ERAS-601 in People With ChordomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, chordoma, neoplasmActive, not recruitingPhase 1 / Phase 22026-04-28NCT06957327
A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic ChordomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, chordoma, neoplasmActive, not recruitingPhase 22026-04-13NCT06787664
Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def TumorsNeoplasms by Histologic Type, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, atypical teratoid rhabdoid tumor, chordoma, mixed neoplasm, neoplasm, rhabdoid tumor, rhabdoid tumor of the kidney, sarcomaActive, not recruitingPhase 1 / Phase 22026-04-13NCT05407441
Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the BoneEwing sarcoma of bone, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, bone disorder, bone sarcoma, chondrosarcoma, chordoma, connective tissue neoplasm, musculoskeletal system disorder, neoplasm, sarcomaRecruitingNot stated2026-03-13NCT05033288
Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull BaseNeoplasms by Histologic Type, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, chondrosarcoma, chordoma, connective tissue neoplasm, neoplasm, sarcomaRecruitingNot applicable2026-01-23NCT05861245
Nivolumab With or Without Stereotactic Radiosurgery in Treating Patients With Recurrent, Advanced, or Metastatic ChordomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, chordoma, neoplasmActive, not recruitingPhase 12026-01-06NCT02989636
Sacral Chordoma: Surgery Versus Definitive Radiation Therapy in Primary Localized DiseaseNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, chordoma, neoplasmRecruitingNot applicable2026-01-02NCT02986516
Pembrolizumab and Pemetrexed for Progressive ChordomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, chordoma, neoplasmRecruitingPhase 22025-01-27NCT06794645
Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton TherapyEwing sarcoma, Neoplasms by Histologic Type, Neoplasms, Bone Tissue, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, chondrosarcoma, chordoma, connective tissue neoplasm, neoplasm, osteosarcoma, sarcomaRecruitingNot applicable2024-09-25NCT06029218
Image Assisted Optimization of Proton Radiation Therapy in Chordomas and ChondrosarcomasNeoplasms by Histologic Type, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, chondrosarcoma, chordoma, connective tissue neoplasm, neoplasm, sarcomaRecruitingNot stated2023-11-18NCT04832620