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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Transcranial Direct Current Stimulation in the Treatment of Primary Progressive AphasiaFrontotemporal Lobar Degeneration, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, aphasia, brain disorder, central nervous system disorder, cognitive disorder, communication disorder, dementia, language disorder, logopenic progressive aphasia, metabolic disease, nervous system disorder, neurodegenerative disease, primary progressive aphasia, progressive non-fluent aphasia, proteostasis deficiencies, psychiatric disorder, speech disorderRecruitingPhase 22026-05-05NCT05386394
The Neurobiology of Two Distinct Types of Progressive Apraxia of SpeechAphasia, Broca, Frontotemporal Lobar Degeneration, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Psychomotor Disorders, Signs and Symptoms, TDP-43 proteinopathy, aphasia, apraxia, brain disorder, central nervous system disorder, cognitive disorder, communication disorder, dementia, language disorder, metabolic disease, nervous system disorder, neurodegenerative disease, primary progressive aphasia, progressive non-fluent aphasia, proteostasis deficiencies, psychiatric disorder, speech disorderRecruitingNot stated2026-05-01NCT03313011
Intervention for Communication Quality of Life in Primary Progressive AphasiaAphasia, Progressive, Aphasia, Semantic, Frontotemporal Lobar Degeneration, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, aphasia, brain disorder, central nervous system disorder, cognitive disorder, communication disorder, dementia, frontotemporal dementia, language disorder, logopenic progressive aphasia, metabolic disease, nervous system disorder, neurodegenerative disease, primary progressive aphasia, progressive non-fluent aphasia, proteostasis deficiencies, psychiatric disorder, semantic dementia, speech disorderRecruitingNot applicable2026-04-21NCT07219680
The Swedish BioFINDER 2 StudyAlzheimer disease, Cognition Disorders, Cognitive Dysfunction, Frontotemporal Lobar Degeneration, Lewy body dementia, Mild Cognitive Impairment, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Ocular Motility Disorders, Parkinson disease, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Pick disease, Signs and Symptoms, TDP-43 proteinopathy, amyotrophic lateral sclerosis, aphasia, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, communication disorder, corticobasal degeneration disorder, cranial nerve neuropathy, dementia, disease, eye disorder, frontotemporal dementia, language disorder, metabolic disease, motor neuron disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, neuromuscular disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, primary progressive aphasia, progressive non-fluent aphasia, progressive supranuclear palsy, progressive supranuclear palsy-parkinsonism syndrome, proteostasis deficiencies, psychiatric disorder, semantic dementia, speech disorder, spinal cord disorder, synucleinopathy, tauopathyRecruitingNot applicable2026-04-06NCT03174938
Language in Primary Progressive AphasiaFrontotemporal Lobar Degeneration, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, aphasia, brain disorder, central nervous system disorder, cognitive disorder, communication disorder, dementia, frontotemporal dementia, language disorder, metabolic disease, nervous system disorder, neurodegenerative disease, primary progressive aphasia, progressive non-fluent aphasia, proteostasis deficiencies, psychiatric disorder, speech disorderRecruitingNot stated2026-02-27NCT00537004
Treatment for Speech and Language in Primary Progressive AphasiaAphasia, Progressive, Frontotemporal Lobar Degeneration, Memory Disorder, Semantic, Memory Disorders, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, aphasia, brain disorder, central nervous system disorder, cognitive disorder, communication disorder, dementia, frontotemporal dementia, language disorder, logopenic progressive aphasia, metabolic disease, nervous system disorder, neurodegenerative disease, primary progressive aphasia, progressive non-fluent aphasia, proteostasis deficiencies, psychiatric disorder, semantic dementia, speech disorderActive, not recruitingNot applicable2025-11-13NCT04881617
Longitudinal Multi-Modality Imaging in Progressive Apraxia of SpeechAphasia, Broca, Frontotemporal Lobar Degeneration, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Psychomotor Disorders, Signs and Symptoms, TDP-43 proteinopathy, aphasia, apraxia, brain disorder, central nervous system disorder, cognitive disorder, communication disorder, dementia, language disorder, metabolic disease, nervous system disorder, neurodegenerative disease, primary progressive aphasia, progressive non-fluent aphasia, proteostasis deficiencies, psychiatric disorder, speech disorderRecruitingPhase 42025-11-12NCT01818661
Primary Progressive Aphasia Multicomponent Language Treatment StudyAphasia, Progressive, Frontotemporal Lobar Degeneration, Memory Disorder, Semantic, Memory Disorders, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, aphasia, brain disorder, central nervous system disorder, cognitive disorder, communication disorder, dementia, frontotemporal dementia, language disorder, logopenic progressive aphasia, metabolic disease, nervous system disorder, neurodegenerative disease, primary progressive aphasia, progressive non-fluent aphasia, proteostasis deficiencies, psychiatric disorder, semantic dementia, speech disorderEnrolling by invitationNot applicable2025-10-08NCT06649084
Diagnosing Frontotemporal Lobar DegenerationFrontotemporal Lobar Degeneration, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, aphasia, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, communication disorder, corticobasal degeneration disorder, cranial nerve neuropathy, dementia, eye disorder, frontotemporal dementia, frontotemporal dementia and/or amyotrophic lateral sclerosis 1, frontotemporal dementia with motor neuron disease, language disorder, metabolic disease, movement disorder, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, primary progressive aphasia, progressive non-fluent aphasia, progressive supranuclear palsy, proteostasis deficiencies, psychiatric disorder, semantic dementia, speech disorder, tauopathyRecruitingNot stated2025-03-30NCT02964637