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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation DisordersCongenital, Hereditary, and Neonatal Diseases and Abnormalities, DNA repair disease, Infant, Newborn, Diseases, Nutritional and Metabolic Diseases, Primary Immunodeficiency Diseases, common variable immunodeficiency, hereditary disease, immune system disorder, inborn error of immunity, metabolic disease, severe combined immunodeficiencyEnrolling by invitationNot stated2026-10-08NCT00895271
Study of IgPro20 to Prevent Infection in People With Multiple Myeloma and HypogammaglobulinemiaBlood Protein Disorders, Hemic and Lymphatic Diseases, Hypogammaglobulinemia, Hypogammaglobulinemia, Acquired, Neoplasms by Histologic Type, agammaglobulinemia, cardiovascular disorder, common variable immunodeficiency, hematologic disorder, hemorrhagic disease, immune system disorder, immunoproliferative disorder, inborn error of immunity, lymphatic system disorder, lymphoproliferative syndrome, monoclonal gammopathy, neoplasm, plasma cell neoplasm, vascular disorder, vascular hemostatic diseaseRecruitingPhase 22026-10-05NCT06976476
Natural History of BronchiectasisAbnormalities, Multiple, Ciliopathies, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Infant, Newborn, Diseases, autoimmune disease, bronchial disorder, bronchiectasis, common variable immunodeficiency, cystic fibrosis, hereditary disease, immune system disorder, inborn error of immunity, lung disorder, otorhinolaryngologic disease, pancreas disorder, primary ciliary dyskinesia, respiratory system disorderRecruitingNot stated2026-10-02NCT00943514
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of ImmunityHemic and Lymphatic Diseases, Infections, Opportunistic Infections, T cell immunodeficiency primary, autoimmune disease, common variable immunodeficiency, immune system disorder, immunoproliferative disorder, inborn error of immunity, lymphatic system disorder, lymphoproliferative syndromeRecruitingPhase 22026-09-28NCT04339777
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesHemic and Lymphatic Diseases, Infections, Opportunistic Infections, T cell immunodeficiency primary, autoimmune disease, common variable immunodeficiency, immune system disorder, immunoproliferative disorder, inborn error of immunity, lymphatic system disorder, lymphoproliferative syndromeRecruitingPhase 22026-09-28NCT02579967
Immunoglobulin for Hypogammaglobulinemia Due to Chimeric Antigen Receptor T Cell TherapyHypogammaglobulinemia, Acquired, common variable immunodeficiency, immune system disorder, inborn error of immunityRecruitingNot stated2026-09-24NCT06989541
Peripheral Helper T-cells in Common Variable ImmunoDeficiencycommon variable immunodeficiency, immune system disorder, inborn error of immunityRecruitingNot applicable2026-08-05NCT07255157
Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Diseasecommon variable immunodeficiency, immune system disorder, inborn error of immunity, interstitial lung disease, lung disorder, respiratory system disorderRecruitingPhase 22026-07-22NCT04925375
Senolytics Treatment of Interstitial Lung Disease in Common Variable Immunodeficiencycommon variable immunodeficiency, immune system disorder, inborn error of immunityActive, not recruitingPhase 22026-06-30NCT05593588
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune DeficienciesBare Lymphocyte Syndrome, Blood Protein Disorders, Chediak-Higashi syndrome, Chronic Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cytopenia, DNA repair disease, Disease Attributes, Eye Diseases, Hereditary, Griscelli syndrome, Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, Infant, Newborn, Diseases, Lymphohistiocytosis, Hemophagocytic, Nutritional and Metabolic Diseases, Omenn syndrome, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Primary Immunodeficiency Diseases, Wiskott-Aldrich syndrome, X-Linked Lymphoproliferative Disorder, X-linked disease, albinism, blood coagulation disease, chronic granulomatous disease, common variable immunodeficiency, dysgammaglobulinemia, eye disorder, hematologic disorder, hemorrhagic disease, hereditary disease, histiocytosis, hyper-IgM syndrome, immune system disorder, immunoproliferative disorder, inborn error of immunity, inherited blood coagulation disorder, interstitial lung disease, leukocyte disorder, leukopenia, lung disorder, lymphatic system disorder, lymphopenia, lymphoproliferative syndrome, metabolic disease, non-Langerhans cell histiocytosis, phagocyte bactericidal dysfunction, respiratory system disorder, reticular dysgenesis, severe combined immunodeficiencyActive, not recruitingNot applicable2026-06-17NCT01652092
IVIG Boya: Safety, Efficacy, and PharmacokineticsBruton-type agammaglobulinemia, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Primary Immunodeficiency Diseases, common variable immunodeficiency, hereditary disease, immune system disorder, inborn error of immunityNot yet recruitingPhase 32026-06-03NCT06150833
Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)22q11.2 deletion syndrome, Abnormalities, Multiple, Blood Protein Disorders, Cardiovascular Abnormalities, Chronic Disease, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, DNA repair disease, DiGeorge syndrome, Digestive System Diseases, Disease Attributes, Hemic and Lymphatic Diseases, Infant, Newborn, Diseases, Lymphatic Abnormalities, Musculoskeletal Abnormalities, Nutritional and Metabolic Diseases, Omenn syndrome, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Primary Immunodeficiency Diseases, X-linked disease, cardiovascular disorder, chromosomal disorder, chronic granulomatous disease, common variable immunodeficiency, congenital heart disease, digestive system disorder, dysgammaglobulinemia, endocrine system disorder, heart disorder, hematologic disorder, hereditary disease, hyper-IgM syndrome, hypoparathyroidism, immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome, immune system disorder, inborn error of immunity, intestinal disorder, leukocyte disorder, lymphatic system disorder, metabolic disease, musculoskeletal system disorder, parathyroid gland disorder, phagocyte bactericidal dysfunction, severe combined immunodeficiencyRecruitingPhase 22026-05-15NCT07284641
Usage of Spirometry in Managing IgG Therapy in CVID With Airway Diseasecommon variable immunodeficiency, immune system disorder, inborn error of immunityRecruitingPhase 42026-05-04NCT05193552
Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationHemic and Lymphatic Diseases, Infections, Opportunistic Infections, T cell immunodeficiency primary, autoimmune disease, common variable immunodeficiency, immune system disorder, immunoproliferative disorder, inborn error of immunity, lymphatic system disorder, lymphoproliferative syndromeActive, not recruitingPhase 22026-03-17NCT03663933
Immune Disorder HSCT Protocol22q11.2 deletion syndrome, Abnormalities, Multiple, Blood Protein Disorders, Bruton-type agammaglobulinemia, Cardiovascular Abnormalities, Chediak-Higashi syndrome, Chronic Disease, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Cytopenia, DNA repair disease, DiGeorge syndrome, Disease Attributes, Eye Diseases, Hereditary, Hemic and Lymphatic Diseases, Infant, Newborn, Diseases, Lymphatic Abnormalities, Lymphohistiocytosis, Hemophagocytic, Musculoskeletal Abnormalities, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Primary Immunodeficiency Diseases, Wiskott-Aldrich syndrome, X-linked disease, albinism, autoimmune disease, autoimmune lymphoproliferative syndrome, blood coagulation disease, cardiovascular disorder, chromosomal disorder, chronic granulomatous disease, common variable immunodeficiency, congenital heart disease, dysgammaglobulinemia, endocrine system disorder, eye disorder, heart disorder, hematologic disorder, hemorrhagic disease, hereditary disease, histiocytosis, hyper-IgM syndrome, hypoparathyroidism, immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome, immune system disorder, immunoproliferative disorder, inborn error of immunity, inherited blood coagulation disorder, leukocyte disorder, leukopenia, lymphatic system disorder, lymphopenia, lymphoproliferative syndrome, metabolic disease, musculoskeletal system disorder, non-Langerhans cell histiocytosis, parathyroid gland disorder, phagocyte bactericidal dysfunction, severe combined immunodeficiencyActive, not recruitingPhase 22026-02-19NCT01821781
Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency DiseasesChronic Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cytopenia, DNA repair disease, Disease Attributes, Hemic and Lymphatic Diseases, Infant, Newborn, Diseases, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Primary Immunodeficiency Diseases, Wiskott-Aldrich syndrome, X-linked disease, blood coagulation disease, chronic granulomatous disease, common variable immunodeficiency, hematologic disorder, hemorrhagic disease, hereditary disease, hyper-IgE recurrent infection syndrome 1, autosomal dominant, immune system disorder, inborn error of immunity, inherited blood coagulation disorder, leukocyte disorder, leukopenia, lymphopenia, metabolic disease, phagocyte bactericidal dysfunction, severe chronic neutropenia, severe combined immunodeficiencyEnrolling by invitationPhase 1 / Phase 22025-12-15NCT01852370
COVID-19 Vaccine Responses in PIDD SubjectsBruton-type agammaglobulinemia, COVID-19, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Coronaviridae Infections, Infections, Nidovirales infectious disease, Orthocoronavirinae infectious disease, Primary Antibody Deficiencies, Primary Immunodeficiency Diseases, RNA Virus Infections, common variable immunodeficiency, hereditary disease, immune system disorder, inborn error of immunity, lung disorder, pneumonia, respiratory system disorder, respiratory tract infectious disorder, viral infectious disease, viral pneumoniaActive, not recruitingNot stated2025-06-03NCT05321407