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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade GliomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), diffuse astrocytoma, epithelial neoplasm, ganglioglioma, glioma, neoplasm, neuroepithelial neoplasm, optic pathway glioma, pilocytic astrocytoma, pilomyxoid astrocytoma, primitive neuroectodermal tumorActive, not recruitingNot applicable2026-09-15NCT04065776
Pediatric Long-Term Follow-up and Rollover StudyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Oligodendroglioma, Childhood, anaplastic astrocytoma, anaplastic ganglioglioma, anaplastic oligodendroglioma, anaplastic pleomorphic xanthoastrocytoma, angiocentric glioma, astrocytoma (excluding glioblastoma), brain disorder, central nervous system cancer, central nervous system disorder, central neurocytoma, cerebellar liponeurocytoma, chordoid glioma of the third ventricle, diffuse astrocytoma, epithelial neoplasm, extraventricular neurocytoma, gangliocytoma, ganglioglioma, glioblastoma, glioma, hereditary disease, hereditary neoplastic syndrome, histiocytosis, inherited neurodegenerative disorder, interstitial lung disease, lung disorder, lymphatic system disorder, neoplasm, nerve sheath neoplasm, nervous system disorder, neuroblastoma, neurocutaneous syndrome, neurodegenerative disease, neuroepithelial neoplasm, neurofibroma, neurofibromatosis, neurofibromatosis type 1, neuromuscular disease, oligodendroglioma, papillary glioneuronal tumor, peripheral nervous system disorder, peripheral nervous system neoplasm, pilocytic astrocytoma, plexiform neurofibroma, primitive neuroectodermal tumor, respiratory system disorder, rosette-forming glioneuronal tumor of fourth ventriculeActive, not recruitingPhase 42026-08-27NCT03975829
Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III GliomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, anaplastic astrocytoma, anaplastic oligoastrocytoma, anaplastic oligodendroglioma, astrocytoma (excluding glioblastoma), diffuse astrocytoma, epithelial neoplasm, glioma, neoplasm, neuroepithelial neoplasm, oligoastrocytoma, oligodendroglioma, primitive neuroectodermal tumorActive, not recruitingPhase 22026-07-28NCT03180502
Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade GliomasHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, anaplastic oligodendroglioma, astrocytoma (excluding glioblastoma), astrocytoma, IDH-mutant, grade 3, astrocytoma, IDH-mutant, grade 4, diffuse astrocytoma, epithelial neoplasm, follicular lymphoma, glioblastoma, glioma, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, malignant glioma, neoplasm, neuroepithelial neoplasm, oligodendroglioma, primitive neuroectodermal tumorRecruitingPhase 1 / Phase 22026-06-24NCT07468136
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsChoroid Plexus Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Teratoid Rhabdoid Tumor, Typical Teratoid Rhabdoid Tumor, anaplastic astrocytoma, anaplastic ependymoma, anaplastic meningioma, anaplastic oligodendroglioma, anaplastic pleomorphic xanthoastrocytoma, astrocytoma (excluding glioblastoma), brain disorder, central nervous system cancer, central nervous system disorder, cerebral ventricle cancer, diffuse astrocytoma, diffuse midline glioma, H3 K27M-mutant, ependymoma, epithelial neoplasm, glioblastoma, glioma, gliomatosis cerebri, gliosarcoma, medulloblastoma, meningioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, oligodendroglioma, pilocytic astrocytoma, pineal body neoplasm, primitive neuroectodermal tumor, tumor of meninges, vascular cancerRecruitingPhase 12025-12-18NCT04541082