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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
A Study of Zanzalintinib in Participants With Recurrent or Progressive MeningiomaNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, brain disorder, central nervous system cancer, central nervous system disorder, meningioma, neoplasm, nervous system disorder, tumor of meninges, vascular cancerRecruitingPhase 22026-10-06NCT07428616
Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal MetastasisNeoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, central nervous system cancer, neoplasm, nervous system disorder, skin disorder, tumor of meningesRecruitingPhase 22026-10-05NCT02422641
Comparing the Radiopharmaceutical Drug, [177Lu]Lu-DOTATATE, to Standard of Care Treatment for Patients With Meningioma That Has Come Back After Prior TreatmentNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, central nervous system cancer, intracranial meningioma, meningioma, neoplasm, nervous system disorder, tumor of meninges, vascular cancerRecruitingPhase 22026-10-02NCT06955169
Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by SurgeryNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, central nervous system cancer, grade II meningioma, intracranial meningioma, meningioma, neoplasm, nervous system disorder, tumor of meninges, vascular cancerActive, not recruitingPhase 32026-10-02NCT03180268
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive MeningiomasNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, central nervous system cancer, intracranial meningioma, meningioma, neoplasm, nervous system disorder, tumor of meninges, vascular cancerRecruitingPhase 22026-10-02NCT02523014
Natural History Study of Patients With Neurofibromatosis Type 2Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Ear Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Otorhinolaryngologic Neoplasms, acoustic neuroma, central nervous system cancer, central nervous system disorder, cranial nerve neoplasm, cranial nerve neuropathy, ependymoma, epithelial neoplasm, glioma, hereditary disease, hereditary neoplastic syndrome, inherited neurodegenerative disorder, meningioma, neoplasm, nerve sheath neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neuroendocrine neoplasm, neuroepithelial neoplasm, neurofibroma, neurofibromatosis, neuroma, otorhinolaryngologic disease, peripheral nervous system neoplasm, primitive neuroectodermal tumor, retrocochlear disease, schwannoma, spinal cord disorder, spinal cord neoplasm, tumor of meninges, vascular cancer, vestibulocochlear nerve disorderRecruitingNot stated2026-10-02NCT00598351
Regorafenib for Recurrent Meningioma (MIRAGE Trial)Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, central nervous system cancer, meningioma, neoplasm, nervous system disorder, tumor of meninges, vascular cancerRecruitingPhase 22026-09-30NCT06275919
Phase II Study of 177Lu-DOTATATE Radionuclide in Adults With Progressive or High-risk MeningiomaNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, central nervous system cancer, meningioma, neoplasm, nervous system disorder, tumor of meninges, vascular cancerActive, not recruitingPhase 22026-09-29NCT03971461
Liquid Biopsy Evaluation and Repository Development at Princess MargaretAdnexal Diseases, Colorectal Neoplasms, Hereditary Nonpolyposis, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cowden disease, DNA repair disease, Digestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Head and Neck Neoplasms, Hemic and Lymphatic Diseases, Lynch syndrome, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Multiple Primary, Neoplasms, Nerve Tissue, Nutritional and Metabolic Diseases, Skin and Connective Tissue Diseases, Thoracic Neoplasms, Urogenital Diseases, Urogenital Neoplasms, benign urinary system neoplasm, breast cancer, breast disorder, breast neoplasm, cancer, central nervous system cancer, colonic disorder, colonic neoplasm, colorectal neoplasm, digestive system disorder, digestive system neoplasm, endocrine system disorder, female reproductive system disorder, female reproductive system neoplasm, gonadal disorder, hamartoma, head and neck cancer, hematologic disorder, hereditary disease, hereditary neoplastic syndrome, immune system disorder, immunoproliferative disorder, intestinal disorder, kidney cancer, kidney disorder, leukemia, lung cancer, lung disorder, lung neoplasm, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, malignant colon neoplasm, malignant endocrine neoplasm, melanocytic neoplasm, melanoma, meningioma, metabolic disease, neoplasm, nervous system disorder, neuroendocrine neoplasm, ovarian cancer, ovarian disorder, plasma cell neoplasm, primitive neuroectodermal tumor, respiratory system disorder, respiratory tract neoplasm, skin disorder, skin neoplasm, tumor of meninges, urinary system disorder, uterine cancer, uterine disorder, vascular cancerRecruitingNot stated2026-09-25NCT03702309
Immune Checkpoint Inhibitor Combined With Pemetrexed Intrathecal Injection for Leptomeningeal Metastasis From Solid TumorsNeoplasms by Site, central nervous system cancer, neoplasm, neoplastic meningitis, nervous system disorder, tumor of meningesActive, not recruitingPhase 1 / Phase 22026-09-24NCT06462222
Combined Intrathecal and Systemic Therapy With Trastuzumab Rezetecan for Leptomeningeal MetastasesNeoplasms by Site, central nervous system cancer, neoplasm, neoplastic meningitis, nervous system disorder, tumor of meningesNot yet recruitingPhase 22026-09-22NCT07833657
Pharmacoscopy for Patients With Refractory Primary Brain TumorsNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, astrocytoma (excluding glioblastoma), central nervous system cancer, ependymoma, epithelial neoplasm, glioblastoma, glioma, medulloblastoma, meningioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumor, tumor of meninges, vascular cancerRecruitingPhase 22026-09-21NCT06804655
Preoperative Embolization for Highly Vascular Brain TumorsBrain Metastases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, brain disorder, capillary hemangioma, central nervous system cancer, central nervous system disorder, hemangioblastoma, hemangioma, meningioma, neoplasm, nervous system disorder, tumor of meninges, vascular cancerNot yet recruitingNot applicable2026-09-17NCT07823985
A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)Neoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, central nervous system cancer, neoplasm, nervous system disorder, skin disorder, triple-negative breast carcinoma, tumor of meningesActive, not recruitingPhase 12026-09-15NCT05809752
Clinico-biological Database in Patients Treated With Metabolic Radiotherapy in the Nuclear Medicine DepartmentGenital Diseases, Head and Neck Neoplasms, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Urogenital Diseases, Urogenital Neoplasms, central nervous system cancer, endocrine system disorder, male reproductive organ cancer, male reproductive system disorder, malignant endocrine neoplasm, meningioma, neoplasm, nervous system disorder, neuroendocrine neoplasm, primitive neuroectodermal tumor, prostate cancer, prostate disorder, thyroid gland disorder, thyroid tumor, tumor of meninges, vascular cancerRecruitingNot applicable2026-09-15NCT04104529
Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-OncologyLeptomeningeal Neoplasms, Neoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorder, tumor of meningesRecruitingNot stated2026-09-14NCT04988009
A Study of SX-682 in Combination With Proton Craniospinal Irradiation (pCSI) in People With Leptomeningeal DiseaseNeoplasms by Site, central nervous system cancer, neoplasm, nervous system disorder, tumor of meningesRecruitingPhase 12026-09-11NCT07814352
China Treatment Trial for Tumor in Sellar Region With Unruptured Intracranial AneurysmCongenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Rathke Cleft Cysts, brain disorder, central nervous system cancer, central nervous system cyst, central nervous system disorder, central nervous system malformation, chordoma, craniopharyngioma, germinoma, hypothalamic disorder, hypothalamic neoplasm, meningioma, neoplasm, nervous system disorder, optic pathway glioma, primitive neuroectodermal tumor, supratentorial cancer, tumor of meninges, vascular cancerNot yet recruitingNot stated2026-09-09NCT07809178
Multiple Dose Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal MetastasesNeoplasm Metastasis, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, central nervous system cancer, neoplasm, neoplastic meningitis, nervous system disorder, tumor of meningesRecruitingPhase 1 / Phase 22026-09-09NCT07098806
UCSD Image-Guided Cognitive-Sparing Radiosurgery for Intracranial LesionsArteriovenous Malformations, Cerebral, Cardiovascular Abnormalities, Central Nervous System Vascular Malformations, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, arteriovenous hemangioma/malformation, arteriovenous malformations of the brain, brain disorder, cancer, cardiovascular disorder, central nervous system cancer, central nervous system disorder, central nervous system malformation, cerebrovascular disorder, intracranial arterial disease, meningioma, neoplasm, nervous system disorder, tumor of meninges, vascular cancer, vascular disorder, vascular malformationRecruitingPhase 22026-09-08NCT04343157
Wearable-Triggered Digital Safety Net for Real-Time Monitoring & Intervention in Leptomeningeal MetastasisNeoplasms by Site, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, central nervous system cancer, neoplasm, neoplastic meningitis, nervous system disorder, tumor of meningesNot yet recruitingNot applicable2026-09-03NCT07704034
B7-H3.CD28Z.CART in CNS NeoplasmsBrain Tumor, Recurrent, Medulloblastoma, Adult, Medulloblastoma, Childhood, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, atypical teratoid rhabdoid tumor, brain disorder, central nervous system cancer, central nervous system disorder, embryonal tumor with multilayered rosettes, ependymoma, epithelial neoplasm, glioma, medulloblastoma, mixed neoplasm, neoplasm, nervous system disorder, neuroepithelial neoplasm, pineal body neoplasm, pineoblastoma, primitive neuroectodermal tumor, rhabdoid tumor, tumor of meningesRecruitingPhase 12026-09-03NCT07390539
Intrathecal Dual Checkpoint Inhibitor (PD-1 and CTLA-4) in Combination With Pemetrexed for Leptomeningeal MetastasisNeoplasms by Site, central nervous system cancer, neoplasm, neoplastic meningitis, nervous system disorder, tumor of meningesActive, not recruitingPhase 1 / Phase 22026-09-02NCT06809530
Intrathecal Combination of Programmed Death-1 (PD-1)/Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Bispecific Antibody and Pemetrexed for Leptomeningeal MetastasisNeoplasms by Site, central nervous system cancer, neoplasm, neoplastic meningitis, nervous system disorder, tumor of meningesActive, not recruitingPhase 1 / Phase 22026-09-02NCT06762080
Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Ear Diseases, NF2-related schwannomatosis, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Otorhinolaryngologic Neoplasms, acoustic neuroma, central nervous system cancer, cranial nerve neoplasm, cranial nerve neuropathy, ependymoma, epithelial neoplasm, glioma, hereditary disease, hereditary neoplastic syndrome, inherited neurodegenerative disorder, meningioma, neoplasm, nerve sheath neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neuroendocrine neoplasm, neuroepithelial neoplasm, neurofibroma, neurofibromatosis, neuroma, otorhinolaryngologic disease, peripheral nervous system neoplasm, primitive neuroectodermal tumor, retrocochlear disease, schwannoma, tumor of meninges, vascular cancer, vestibulocochlear nerve disorderRecruitingPhase 22026-09-02NCT04374305