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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial DysfunctionChandler syndrome, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Corneal Endothelial Cell Loss, Corneal Endothelial Dystrophy 1, Eye Diseases, Hereditary, Eye Manifestations, Fuchs' endothelial dystrophy, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Signs and Symptoms, congenital hereditary endothelial dystrophy of cornea, corneal disorder, corneal dystrophy, corneal edema, eye disorder, hereditary diseaseRecruitingPhase 22026-10-09NCT07729137
A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal EctasiaCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Dilatation, Pathologic, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, corneal disorder, corneal dystrophy, eye disorder, hereditary disease, keratoconusRecruitingNot stated2026-10-08NCT02118922
DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingPhase 22026-09-28NCT07024693
The Belgian Endothelial Surgical Transplant of the CorneaCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, bullous keratopathy, corneal disorder, corneal dystrophy, corneal edema, eye disorder, hereditary diseaseActive, not recruitingNot applicable2026-09-14NCT05436665
Safety and Efficacy Study of GEB-101 Injection in Subjects With TGFBI-related Corneal DystrophyAmyloid Neuropathies, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Nutritional and Metabolic Diseases, Thiel-Behnke corneal dystrophy, amyloidosis, corneal disorder, corneal dystrophy, eye disorder, familial amyloid neuropathy, hereditary amyloidosis, hereditary disease, inborn errors of metabolism, inherited neurodegenerative disorder, metabolic disease, nervous system disorder, neurodegenerative disease, neuromuscular disease, peripheral nervous system disorder, proteostasis deficienciesNot yet recruitingPhase 1 / Phase 22026-09-10NCT07750678
The Effect of Topical Rho-kinase Inhibitors on Corneas of Patients With Fuchs Endothelial Corneal DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, cataract, corneal disorder, corneal dystrophy, corneal edema, eye disorder, glaucoma, hereditary disease, lens disorder, ocular hypertensionEnrolling by invitationNot stated2026-09-09NCT06969586
Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingPhase 22026-09-02NCT04440280
Partial Range Of Field IOLs in DMEK-Enabled ProceduresCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, cataract, corneal disorder, corneal dystrophy, eye disorder, hereditary disease, lens disorderNot yet recruitingNot applicable2026-08-25NCT07441616
Descemet Endothelial Thickness Comparison Trial IICongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingPhase 32026-08-17NCT05275972
Postoperative CCT in FECD vs. Non-FECDCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, cataract, corneal disorder, corneal dystrophy, eye disorder, hereditary disease, lens disorderNot yet recruitingNot stated2026-08-10NCT07731945
Fresh Corneal Lenticule Implantation in Macular Corneal Distrophy With Relex Smile SurgeryCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, corneal disorder, corneal dystrophy, eye disorder, hereditary disease, macular corneal dystrophyEnrolling by invitationNot applicable2026-07-29NCT04642729
Prognosis of Posterior Lamellar KeratoplastyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot stated2026-06-24NCT06859411
National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic DiseasesCongenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Abnormalities, Eye Diseases, Hereditary, Nutritional and Metabolic Diseases, Skin and Connective Tissue Diseases, albinism, aniridia, blue cone monochromacy, corneal disorder, corneal dystrophy, eye disorder, hereditary disease, hereditary skin disorder, hypopigmentation of the skin, inborn disorder of amino acid metabolism, inborn errors of metabolism, iris disorder, macular degeneration, metabolic disease, retinal degeneration, retinal disorder, skin disorder, skin pigmentation disorder, uveal disorder, vitelliform macular dystrophy, vitiligoRecruitingNot stated2026-06-09NCT06491615
Effect of Descemet Membrane Polishing in Fuchs Endothelial Corneal DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot applicable2026-05-26NCT07539012
Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in FranceCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Corneal Dystrophy, Posterior Polymorphous, 1, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot stated2026-05-06NCT05742321
Plasma Rich in Growth Factors in Corneal Endothelial TransplantationCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, corneal edema, eye disorder, hereditary diseaseRecruitingNot applicable2026-04-09NCT06261346
Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 YearsCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseEnrolling by invitationNot applicable2026-02-27NCT07217249
Influence of Supine Positioning on the Outcomes After Descemet Membrane Endothelial Keratoplasty (DMEK)Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot applicable2026-01-28NCT07373821
PVEK Corneal Implant For Treatment of Corneal EdemaCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, corneal edema, eye disorder, hereditary diseaseRecruitingPhase 12026-01-12NCT07325097
Study to Assess Safety and Tolerability of Multiple Doses of EO2002Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Corneal Dystrophy, Posterior Polymorphous, 1, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, bullous keratopathy, corneal disorder, corneal dystrophy, corneal edema, corneal endothelial dystrophy, eye disorder, hereditary diseaseRecruitingPhase 12025-12-08NCT05636579
SUCCESS Score Validation in Fuchs DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot stated2025-12-04NCT07265388
High Resolution, High-speed Multimodal Ophthalmic ImagingCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Nutritional and Metabolic Diseases, age-related macular degeneration, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, corneal disorder, corneal dystrophy, diabetes mellitus, dry eye syndrome, endocrine system disorder, eye disorder, glaucoma, glucose metabolism disease, hereditary disease, hypertensive disorder, inherited retinal dystrophy, injury, keratoconus, lacrimal apparatus disorder, macular degeneration, macular retinal edema, metabolic disease, nervous system disorder, ocular hypertension, retinal degeneration, retinal detachment, retinal disorder, retinitis pigmentosa, stroke disorder, vascular disorderRecruitingNot applicable2025-11-18NCT04129021
The OPTIMISE StudyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingPhase 42025-10-06NCT05716945
Safety and Efficacy of Tissue Engineered Endothelial KeratoplastyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, bullous keratopathy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingPhase 12025-09-12NCT04319848
OCT in Fuchs' DystrophyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Fuchs' endothelial dystrophy, corneal disorder, corneal dystrophy, eye disorder, hereditary diseaseRecruitingNot stated2025-09-09NCT04258787