Cushing syndrome
Cushing syndrome
Explore linked clinical trials. Standard reference: MONDO:001891241 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome | ACTH-dependent Cushing syndrome, Cushing syndrome, Neoplasms by Histologic Type, Neoplasms by Site, Nutritional and Metabolic Diseases, Paraneoplastic Endocrine Syndromes, adenocarcinoma, adrenal cortex disorder, adrenal cortex neoplasm, adrenal gland cancer, adrenal gland disorder, adrenal gland hyperfunction, brain disorder, carcinoma, cardiovascular disorder, central nervous system disorder, diabetes mellitus, ectopic ACTH secretion syndrome, endocrine system disorder, epithelial neoplasm, glucose metabolism disease, hyperpituitarism, hypertensive disorder, hypothalamic disorder, malignant endocrine neoplasm, metabolic disease, neoplasm, nervous system disorder, paraneoplastic syndrome, pituitary gland disorder, type 2 diabetes mellitus, vascular disorder | Active, not recruiting | Phase 2 | 2026-10-09 | NCT03604198 | |
| Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D) | Cushing syndrome, Nutritional and Metabolic Diseases, Paraneoplastic Endocrine Syndromes, adrenal gland disorder, adrenal gland hyperfunction, diabetes mellitus, ectopic ACTH secretion syndrome, endocrine system disorder, glucose metabolism disease, metabolic disease, neoplasm, paraneoplastic syndrome, type 2 diabetes mellitus | Recruiting | Phase 2 | 2026-10-06 | NCT07296484 | |
| Prospective Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Ectopic Cushing Syndrome | Cushing syndrome, adrenal gland disorder, adrenal gland hyperfunction, endocrine system disorder | Recruiting | Phase 2 | 2026-10-02 | NCT02019706 | |
| Evaluation of Adults With Endocrine and Metabolic-Related Conditions | Cushing syndrome, adrenal gland disorder, adrenal gland hyperfunction, endocrine system disorder | Recruiting | Not stated | 2026-09-28 | NCT02830308 | |
| Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACS | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cushing syndrome, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Nutritional and Metabolic Diseases, Paraneoplastic Endocrine Syndromes, Urogenital Abnormalities, Urogenital Diseases, adrenal gland disorder, adrenal gland hyperfunction, adrenogenital syndrome, congenital adrenal hyperplasia, disorder of sexual differentiation, ectopic ACTH secretion syndrome, endocrine system disorder, gonadal disorder, hereditary disease, inborn errors of metabolism, metabolic disease, neoplasm, paraneoplastic syndrome, steroid inherited metabolic disorder | Recruiting | Phase 2 | 2026-09-25 | NCT07138274 | |
| Metyrapone for Mild Autonomous Cortisol Secretion (MACS) | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cushing syndrome, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Nutritional and Metabolic Diseases, Paraneoplastic Endocrine Syndromes, Urogenital Abnormalities, Urogenital Diseases, adrenal gland disorder, adrenal gland hyperfunction, adrenogenital syndrome, congenital adrenal hyperplasia, disorder of sexual differentiation, ectopic ACTH secretion syndrome, endocrine system disorder, gonadal disorder, hereditary disease, inborn errors of metabolism, metabolic disease, neoplasm, paraneoplastic syndrome, steroid inherited metabolic disorder | Active, not recruiting | Phase 2 | 2026-09-25 | NCT06106295 | |
| Evaluating the Functional Status of the Adrenal Glands With [68Ga]Ga-PentixaFor in Hyperaldosteronism and Hypercortisolism | Cushing syndrome, Neoplasms by Histologic Type, adenoma, adrenal gland disorder, adrenal gland hyperfunction, endocrine system disorder, epithelial neoplasm, hyperaldosteronism, neoplasm | Recruiting | Phase 2 | 2026-09-23 | NCT06246357 | |
| Recovery From Cushing Syndrome and Mild Autonomous Cortisol Secretion (MACS) | ACTH-dependent Cushing syndrome, Cushing syndrome, adrenal gland disorder, adrenal gland hyperfunction, brain disorder, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, nervous system disorder, pituitary gland disorder | Recruiting | Not stated | 2026-09-18 | NCT04543253 | |
| A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement | Cushing syndrome, adrenal gland disorder, adrenal gland hyperfunction, adrenocortical insufficiency, endocrine system disorder, endogenous Cushing syndrome | Recruiting | Not stated | 2026-09-09 | NCT06430528 | |
| Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing Syndrome | Cushing syndrome, Pathologic Processes, Pathological Conditions, Signs and Symptoms, adrenal gland disorder, adrenal gland hyperfunction, disease, endocrine system disorder | Recruiting | Phase 2 | 2026-08-31 | NCT06635629 | |
| A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome | ACTH-dependent Cushing syndrome, Cushing syndrome, Paraneoplastic Endocrine Syndromes, adrenal gland disorder, adrenal gland hyperfunction, brain disorder, central nervous system disorder, ectopic ACTH secretion syndrome, endocrine system disorder, hyperpituitarism, hypothalamic disorder, neoplasm, nervous system disorder, paraneoplastic syndrome, pituitary gland disorder | Active, not recruiting | Phase 1 / Phase 2 | 2026-08-19 | NCT05804669 | |
| EndoSense: Continuous Real-Time Monitoring of Health Markers in Endocrine and Metabolic Disorders | Body Weight, Cushing syndrome, Nutritional and Metabolic Diseases, Overweight, Paraneoplastic Endocrine Syndromes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, adrenal gland disorder, adrenal gland hyperfunction, cardiovascular disorder, ectopic ACTH secretion syndrome, endocrine system disorder, hyperaldosteronism, hypertensive disorder, neoplasm, nutritional disorder, obesity disorder, overnutrition, paraneoplastic syndrome, primary aldosteronism, vascular disorder | Active, not recruiting | Not applicable | 2026-07-27 | NCT07727356 | |
| Salivary Cortisol and Hypercortisolism in Type 2 Diabetes | Cushing syndrome, Nutritional and Metabolic Diseases, adrenal gland disorder, adrenal gland hyperfunction, diabetes mellitus, endocrine system disorder, glucose metabolism disease, metabolic disease, type 2 diabetes mellitus | Recruiting | Not stated | 2026-07-27 | NCT07156370 | |
| Myokines as Potential Biomarkers and Drivers of Sarcopenia in Metabolic and Endocrine Diseases | Atrophy, Body Weight, Cushing syndrome, Neurologic Manifestations, Neuromuscular Manifestations, Nutritional and Metabolic Diseases, Overweight, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Sarcopenia, Signs and Symptoms, adrenal gland disorder, adrenal gland hyperfunction, diabetes mellitus, endocrine system disorder, glucose metabolism disease, metabolic disease, muscular atrophy, nervous system disorder, nutritional disorder, obesity disorder, overnutrition | Recruiting | Not stated | 2026-07-14 | NCT07703683 | |
| NAC- NAFLD And Cushing | Cushing syndrome, Digestive System Diseases, adrenal gland disorder, adrenal gland hyperfunction, endocrine system disorder, fatty liver disease, liver disorder, metabolic dysfunction-associated steatotic liver disease | Recruiting | Not applicable | 2026-07-10 | NCT05881005 | |
| Genomic and Metabolomic Markers Reflecting the Complications of Hypercortisolism (CUSHINGOMICS) | Cushing syndrome, adrenal gland disorder, adrenal gland hyperfunction, adrenocortical insufficiency, endocrine system disorder | Active, not recruiting | Not applicable | 2026-05-20 | NCT04840693 | |
| Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism | Cushing syndrome, Neoplasms by Site, adrenal cortex adenoma, adrenal cortex disorder, adrenal cortex neoplasm, adrenal gland cancer, adrenal gland disorder, adrenal gland hyperfunction, endocrine system disorder, hyperaldosteronism, malignant endocrine neoplasm, neoplasm, primary aldosteronism | Recruiting | Not applicable | 2026-05-08 | NCT05368090 | |
| Adrenal Tumors - Pathogenesis and Therapy | Cushing syndrome, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, adenocarcinoma, adrenal cortex disorder, adrenal cortex neoplasm, adrenal gland cancer, adrenal gland disorder, adrenal gland hyperfunction, carcinoma, endocrine system disorder, epithelial neoplasm, hyperaldosteronism, malignant endocrine neoplasm, neoplasm, neuroendocrine neoplasm, paraganglioma, pheochromocytoma, primary aldosteronism, primitive neuroectodermal tumor | Recruiting | Not stated | 2026-05-07 | NCT00669266 | |
| Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma | Cushing syndrome, Neoplasms by Histologic Type, Neoplasms by Site, adenocarcinoma, adrenal cortex disorder, adrenal cortex neoplasm, adrenal gland cancer, adrenal gland disorder, adrenal gland hyperfunction, carcinoma, endocrine system disorder, epithelial neoplasm, malignant endocrine neoplasm, neoplasm | Active, not recruiting | Not stated | 2026-05-07 | NCT00457587 | |
| IMPACT-MACS: Adrenalectomy vs Semaglutide for Metabolic Outcomes in Mild Autonomous Cortisol Secretion | Adrenal incidentaloma, Body Weight, Body Weight Changes, Cushing syndrome, Insulin Resistance, Nutritional and Metabolic Diseases, Paraneoplastic Endocrine Syndromes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Weight Loss, adrenal gland disorder, adrenal gland hyperfunction, ectopic ACTH secretion syndrome, endocrine system disorder, glucose metabolism disease, hyperinsulinism, metabolic disease, neoplasm, paraneoplastic syndrome | Recruiting | Not applicable | 2026-03-27 | NCT07361874 | |
| Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Syndrome | Cushing syndrome, adrenal gland disorder, adrenal gland hyperfunction, brain disorder, central nervous system disorder, endocrine system disorder, hypothalamic disorder, nervous system disorder, pituitary gland disorder | Recruiting | Phase 2 | 2026-03-27 | NCT03708900 | |
| REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD) | Body Weight, Bone Diseases, Developmental, Bone Diseases, Endocrine, Bone Diseases, Metabolic, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cushing syndrome, Dwarfism, Nutritional and Metabolic Diseases, Osteopenia, Overweight, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Skin and Connective Tissue Diseases, adrenal gland disorder, adrenal gland hyperfunction, bone disorder, brain disorder, central nervous system disorder, connective tissue disorder, endocrine system disorder, hereditary disease, hypopituitarism, hypothalamic disorder, metabolic disease, musculoskeletal system disorder, neoplasm, nervous system disorder, nutritional deficiency disease, nutritional disorder, obesity disorder, osteochondrodysplasia, osteogenesis imperfecta, osteoporosis, overnutrition, pituitary dwarfism, pituitary gland disorder | Recruiting | Not applicable | 2026-02-17 | NCT07412782 | |
| Impact of 1 mg Osilodrostat Therapy on Mild Autonomous Cortisol Secretion (MACS) | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cushing syndrome, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Nutritional and Metabolic Diseases, Paraneoplastic Endocrine Syndromes, Urogenital Abnormalities, Urogenital Diseases, adrenal gland disorder, adrenal gland hyperfunction, adrenogenital syndrome, congenital adrenal hyperplasia, disorder of sexual differentiation, ectopic ACTH secretion syndrome, endocrine system disorder, gonadal disorder, hereditary disease, inborn errors of metabolism, metabolic disease, neoplasm, paraneoplastic syndrome, steroid inherited metabolic disorder | Recruiting | Phase 2 | 2026-02-11 | NCT07104812 | |
| Institutional Registry of Rare Diseases | Abnormalities, Multiple, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, Cardiovascular Abnormalities, Ciliopathies, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cushing syndrome, Digestive System Abnormalities, Digestive System Diseases, Disease Attributes, Eosinophilia, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Gaucher disease, Hemic and Lymphatic Diseases, Hereditary Complement Deficiency Diseases, Hirschsprung disease, Hypersensitivity, Delayed, Hypersensitivity, Immediate, Immunoglobulin G4-Related Disease, Imprinting Disorders, Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Lysosomal Storage Diseases, Nervous System, Male Urogenital Diseases, Mast Cell Activation Disorders, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Multiple Primary, Neoplasms, Nerve Tissue, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Overweight, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Prader-Willi syndrome, Primary Immunodeficiency Diseases, Rare Diseases, Skin Abnormalities, Skin and Connective Tissue Diseases, Urogenital Abnormalities, Urogenital Diseases, Wilson disease, adrenal gland disorder, adrenal gland hyperfunction, adrenogenital syndrome, amyloidosis, angioedema, angiomatosis, aortic valve disorder, aortic valve stenosis, autoimmune disease, basal ganglia disorder, brain disorder, cardiomyopathy, cardiovascular disorder, central nervous system disorder, chromosomal disorder, colonic disorder, congenital adrenal hyperplasia, connective tissue neoplasm, demyelinating disease, digestive system disorder, disorder of sexual differentiation, ectodermal dysplasia syndrome, endocrine system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, gonadal disorder, heart disorder, heart valve disorder, hematologic disorder, hemorrhagic disease, hereditary angioedema, hereditary disease, hereditary hemorrhagic telangiectasia, hereditary neoplastic syndrome, hereditary skin disorder, hypertensive disorder, hypertrophic cardiomyopathy, immune system disorder, inborn error of immunity, inborn errors of metabolism, inborn metal metabolism disorder, inflammatory bowel disease, inherited neurodegenerative disorder, intellectual disability, intestinal disorder, leukocyte disorder, liver disorder, lung disorder, lymphatic system disorder, lymphoproliferative syndrome, lysosomal lipid storage disorder, lysosomal storage disease, malignant endocrine neoplasm, mastocytosis, megacolon, metabolic disease, movement disorder, multiple endocrine neoplasia, neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neuroendocrine neoplasm, nutritional disorder, obesity disorder, overnutrition, paraganglioma, pheochromocytoma, primitive neuroectodermal tumor, proteostasis deficiencies, pulmonary hypertension, respiratory system disorder, sarcoidosis, skin disorder, skin vascular disease, sphingolipidosis, steroid inherited metabolic disorder, subvalvular aortic stenosis, telangiectasis, urticaria, vascular disorder, vascular hemostatic disease, vascular malformation, von Hippel-Lindau disease | Recruiting | Not stated | 2026-01-14 | NCT06573723 | |
| Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome | Cushing syndrome, Paraneoplastic Endocrine Syndromes, adrenal gland disorder, adrenal gland hyperfunction, cardiovascular disorder, ectopic ACTH secretion syndrome, endocrine system disorder, hypertensive disorder, neoplasm, paraneoplastic syndrome, vascular disorder | Not yet recruiting | Phase 4 | 2025-12-10 | NCT07247162 |