osteogenesis imperfecta
osteogenesis imperfecta
Explore linked clinical trials. Standard reference: MONDO:001901926 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Setrusumab vs Placebo for Osteogenesis Imperfecta | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Active, not recruiting | Phase 2 / Phase 3 | 2026-10-06 | NCT05125809 | |
| Setrusumab in Pediatric Japanese Subjects With Osteogenesis Imperfecta | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Active, not recruiting | Phase 3 | 2026-09-28 | NCT06636071 | |
| A Dose REgimen-Finding Study of AGA2115 in Chinese Patients With Osteogenesis ImpeRfecta (EIR) | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Recruiting | Phase 2 | 2026-09-22 | NCT07557446 | |
| BBD Longitudinal Study of Osteogenesis Imperfecta | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, brittle bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta, osteogenesis imperfecta type 5 | Recruiting | Not stated | 2026-09-01 | NCT02432625 | |
| Clear Aligners for the Treatment of Dental Malocclusion in OI | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Active, not recruiting | Not applicable | 2026-08-18 | NCT04815564 | |
| Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 GeNetic Variations (IDUN) | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Recruiting | Phase 2 | 2026-08-17 | NCT07062588 | |
| Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical Diagnosis | Bone Diseases, Developmental, Bone Diseases, Metabolic, Collagen Diseases, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Hypophosphatemia, Familial, Male Urogenital Diseases, Nutritional and Metabolic Diseases, Skin and Connective Tissue Diseases, Stomatognathic Diseases, Stomatognathic System Abnormalities, Tooth Abnormalities, Urogenital Diseases, X-linked hypophosphatemic rickets, bone disorder, calcium metabolic disease, connective tissue disorder, cutaneous mucinosis, hereditary disease, hypophosphatemia, hypophosphatemic rickets, inborn carbohydrate metabolic disorder, inborn errors of metabolism, inborn metal metabolism disorder, kidney disorder, lysosomal storage disease, metabolic disease, mucopolysaccharidosis, musculoskeletal system disorder, nutritional deficiency disease, nutritional disorder, osteochondrodysplasia, osteogenesis imperfecta, phosphorus metabolism disease, renal tubular transport disease, rickets, tooth disorder, urinary system disorder, vitamin D deficiency, vitamin deficiency disorder | Not yet recruiting | Not applicable | 2026-06-24 | NCT07666269 | |
| Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Recruiting | Phase 3 | 2026-06-22 | NCT07366086 | |
| Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Active, not recruiting | Phase 3 | 2026-05-27 | NCT05972551 | |
| GRACE II (General Retrospective Analysis of Commercial Experience With AGN1 LOEP) | Bone Diseases, Developmental, Bone Diseases, Metabolic, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Femoral Fractures, Hip Injuries, Leg Injuries, Nutritional and Metabolic Diseases, Skin and Connective Tissue Diseases, bone disorder, bone fracture, connective tissue disorder, hereditary disease, hip fracture, hypophosphatasia, inborn errors of metabolism, inborn metal metabolism disorder, injury, metabolic disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta, osteoporosis | Not yet recruiting | Not stated | 2026-05-19 | NCT07594639 | |
| Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Osteogenesis Imperfecta | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Recruiting | Not applicable | 2026-05-08 | NCT05927389 | |
| Mesenchymal Cell Therapy in Osteogenesis Imperfecta (OI) | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta, osteogenesis imperfecta type 3 | Not yet recruiting | Phase 1 / Phase 2 | 2026-05-08 | NCT05559801 | |
| Effects of Bisphosphonates on OI-Related Hearing Loss | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Ear Diseases, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, Skin and Connective Tissue Diseases, bone disorder, brittle bone disorder, connective tissue disorder, cutaneous mucinosis, hearing disorder, hearing loss disorder, hereditary disease, inborn carbohydrate metabolic disorder, inborn errors of metabolism, lysosomal storage disease, metabolic disease, mucopolysaccharidosis, mucopolysaccharidosis type 4, musculoskeletal system disorder, nervous system disorder, osteochondrodysplasia, osteogenesis imperfecta, otorhinolaryngologic disease | Recruiting | Phase 4 | 2026-04-28 | NCT04152551 | |
| An Interventional Study to Evaluate the Impact of Blood Flow Restriction Training on Muscle, Bone, and Quality of Life in Adults With Osteogenesis Imperfecta Type I | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Lobstein's Disease, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Recruiting | Not applicable | 2026-03-17 | NCT07478224 | |
| Cardiopulmonary Outcomes in Osteogenesis Imperfecta: BBD7708 | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Active, not recruiting | Not stated | 2026-03-02 | NCT05317637 | |
| Setrusumab vs Bisphosphonates in Pediatric Subjects With Osteogenesis Imperfecta | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Active, not recruiting | Phase 3 | 2026-02-25 | NCT05768854 | |
| REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD) | Body Weight, Bone Diseases, Developmental, Bone Diseases, Endocrine, Bone Diseases, Metabolic, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cushing syndrome, Dwarfism, Nutritional and Metabolic Diseases, Osteopenia, Overweight, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Skin and Connective Tissue Diseases, adrenal gland disorder, adrenal gland hyperfunction, bone disorder, brain disorder, central nervous system disorder, connective tissue disorder, endocrine system disorder, hereditary disease, hypopituitarism, hypothalamic disorder, metabolic disease, musculoskeletal system disorder, neoplasm, nervous system disorder, nutritional deficiency disease, nutritional disorder, obesity disorder, osteochondrodysplasia, osteogenesis imperfecta, osteoporosis, overnutrition, pituitary dwarfism, pituitary gland disorder | Recruiting | Not applicable | 2026-02-17 | NCT07412782 | |
| Dental Malocclusion and Craniofacial Development in OI | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Active, not recruiting | Not stated | 2026-01-27 | NCT02934451 | |
| Prospective Observational Cohort Study of Cardiac Structure and Function in Children and Adults With Osteogenesis Imperfecta | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Recruiting | Not stated | 2025-12-17 | NCT07287241 | |
| Urinary Biomarkers of OI Pathobiology | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Active, not recruiting | Not stated | 2025-12-01 | NCT02531087 | |
| Registry of Osteogenesis Imperfecta | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Recruiting | Not stated | 2025-11-20 | NCT04115774 | |
| Pediatric Arthropathy Beyond Inflammation: Clinical Spectrum and Diagnostic Approach at Assiut University Children Hospital | Bone Diseases, Developmental, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Farber lipogranulomatosis, Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Lysosomal Storage Diseases, Nervous System, Nutritional and Metabolic Diseases, Osteolysis, Essential, Osteolysis, Idiopathic Multicentric, Skin and Connective Tissue Diseases, bone disorder, bone resorption disease, brain disorder, central nervous system disorder, connective tissue disorder, cutaneous mucinosis, hereditary disease, hereditary skin disorder, hyaline fibromatosis syndrome, inborn carbohydrate metabolic disorder, inborn errors of metabolism, infantile systemic hyalinosis, lysosomal lipid storage disorder, lysosomal storage disease, lytic metastatic bone lesion, metabolic disease, mucopolysaccharidosis, musculoskeletal system disorder, nervous system disorder, osteochondrodysplasia, osteogenesis imperfecta, progressive pseudorheumatoid arthropathy of childhood, skin disorder, sphingolipidosis | Not yet recruiting | Not stated | 2025-09-15 | NCT07173010 | |
| Audio-vestibular Evaluation of Children and Young Adults With Osteogenesis Imperfecta | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Recruiting | Not stated | 2025-09-12 | NCT05419960 | |
| Boost Brittle Bones Before Birth | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Active, not recruiting | Phase 1 / Phase 2 | 2025-09-12 | NCT03706482 | |
| Social Cognition in Dystrophinopathies and Neurodevelopmental Disorders | Bone Diseases, Developmental, CGF1, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Duchenne muscular dystrophy, Muscular Disorders, Atrophic, Skin and Connective Tissue Diseases, X-linked disease, bone disorder, connective tissue disorder, hereditary disease, muscle tissue disorder, muscular dystrophy, musculoskeletal system disorder, nervous system disorder, neuromuscular disease, osteochondrodysplasia, osteogenesis imperfecta | Not yet recruiting | Not stated | 2025-03-13 | NCT06874166 |