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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Ewing sarcoma, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, Male Urogenital Diseases, Myosarcoma, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Bone Tissue, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Skin and Connective Tissue Diseases, Urogenital Diseases, Urogenital Neoplasms, Wilms tumor, benign urinary system neoplasm, central nervous system cancer, connective tissue neoplasm, ependymoma, epithelial neoplasm, glioma, hepatoblastoma, hereditary disease, hereditary neoplastic syndrome, histiocytic sarcoma, histiocytosis, immune system disorder, immunoproliferative disorder, interstitial lung disease, juvenile xanthogranuloma, kidney cancer, kidney disorder, lung disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, malignant glioma, malignant histiocytosis, medulloblastoma, mixed neoplasm, myomatous neoplasm, neoplasm, nervous system disorder, neuroblastoma, neuroepithelial neoplasm, non-Langerhans cell histiocytosis, osteosarcoma, primitive neuroectodermal tumor, respiratory system disorder, rhabdoid tumor, rhabdomyosarcoma, sarcoma, skin disorder, urinary system disorderActive, not recruitingPhase 22026-07-24NCT03155620
Lenalidomide for Adult Histiocyte DisordersErdheim-Chester disease, Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, Neoplasms by Histologic Type, histiocytic sarcoma, histiocytosis, interstitial lung disease, lung disorder, lymphatic system disorder, malignant histiocytosis, neoplasm, non-Langerhans cell histiocytosis, respiratory system disorderActive, not recruitingPhase 22026-07-23NCT02523040
CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide GeneChronic Disease, Disease Attributes, Hemic and Lymphatic Diseases, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Lymphohistiocytosis, Hemophagocytic, Myeloproliferative Disorders, Neoplasms by Histologic Type, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, bone marrow disorder, hematologic disorder, histiocytic sarcoma, histiocytosis, immune system disorder, immunoproliferative disorder, leukemia, lymphatic system disorder, lymphoid leukemia, lymphoma, lymphoproliferative syndrome, malignant histiocytosis, myelodysplastic syndrome, myeloid leukemia, neoplasm, non-Hodgkin lymphoma, non-Langerhans cell histiocytosisActive, not recruitingPhase 12026-07-01NCT00710892
Histiocytic Disorder Follow-up StudyErdheim-Chester disease, Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, Histiocytosis, Malignant, Neoplasms by Histologic Type, Neoplasms, Second Primary, histiocytic sarcoma, histiocytosis, interstitial lung disease, lung disorder, lymphatic system disorder, malignant histiocytosis, neoplasm, non-Langerhans cell histiocytosis, respiratory system disorder, sinus histiocytosis with massive lymphadenopathy, xanthogranulomaRecruitingNot stated2026-06-12NCT05915208
Q702 for the Treatment of Patients With Hematologic MalignanciesB-cell chronic lymphocytic leukemia, B-cell neoplasm, Blood Protein Disorders, CD4+/CD56+ hematodermic neoplasm, Chronic Disease, Disease Attributes, Erdheim-Chester disease, Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, Leukemia, B-Cell, Lymphoma, B-Cell, Marginal Zone, Myeloproliferative Disorders, Neoplasms by Histologic Type, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, T-cell non-Hodgkin lymphoma, Waldenstrom macroglobulinemia, bone marrow disorder, cardiovascular disorder, chronic myelomonocytic leukemia, follicular lymphoma, hematologic disorder, hematopoietic and lymphoid system neoplasm, hemorrhagic disease, histiocytic sarcoma, histiocytosis, immune system disorder, immunoproliferative disorder, interdigitating dendritic cell sarcoma, interstitial lung disease, leukemia, lung disorder, lymphatic system disorder, lymphoid leukemia, lymphoma, lymphoproliferative syndrome, malignant histiocytosis, monoclonal gammopathy, myelodysplastic syndrome, myelodysplastic/myeloproliferative disease, myeloid leukemia, neoplasm, non-Langerhans cell histiocytosis, peripheral T-cell lymphoma, not otherwise specified, plasma cell neoplasm, primary central nervous system lymphoma, primary cutaneous T-cell non-Hodgkin lymphoma, primary myelofibrosis, respiratory system disorder, skin disorder, skin neoplasm, vascular disorder, vascular hemostatic diseaseRecruitingPhase 12025-10-10NCT06712810
Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic DisordersErdheim-Chester disease, Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, Neoplasms by Histologic Type, Skin and Connective Tissue Diseases, histiocytic sarcoma, histiocytosis, interstitial lung disease, juvenile xanthogranuloma, lung disorder, lymphatic system disorder, malignant histiocytosis, neoplasm, non-Langerhans cell histiocytosis, respiratory system disorder, sinus histiocytosis with massive lymphadenopathy, skin disorderRecruitingPhase 22025-09-18NCT04079179