patent foramen ovale
patent foramen ovale
Explore linked clinical trials. Standard reference: MONDO:002043949 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Migraine Headaches Elimination With Patent Foramen Ovale-Directed Therapy | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, congenital heart disease, headache disorder, heart disorder, heart septal defect, hypnic headache, migraine disorder, nervous system disorder, patent foramen ovale | Recruiting | Phase 3 | 2026-10-08 | NCT07629635 | |
| Comparing Two PFO Closure Devices in Adults With Previous Stroke or TIA | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, brain disorder, brain ischemia, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, ischemic stroke, nervous system disorder, patent foramen ovale, stroke disorder, transient ischemic attack, vascular disorder | Recruiting | Not applicable | 2026-10-05 | NCT07380490 | |
| WSO BEAT STROKE Initiative | Arrhythmias, Cardiac, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Pathologic Processes, Pathological Conditions, Signs and Symptoms, atrial fibrillation, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Not yet recruiting | Not applicable | 2026-09-18 | NCT06606054 | |
| International Multicenter Patent foRamen OVale & strokE (IMPROVE) Registry | Arrhythmias, Cardiac, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Pathologic Processes, Pathological Conditions, Signs and Symptoms, atrial fibrillation, atrial flutter, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Active, not recruiting | Not stated | 2026-09-18 | NCT04738071 | |
| Dapagliflozin and Right Heart Recovery After ASD Device Closure | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, cardiovascular disorder, congenital heart disease, heart disorder, heart septal defect, patent foramen ovale | Not yet recruiting | Not applicable | 2026-09-17 | NCT07823972 | |
| Assessment of Flecainide to Lower the Patent Foramen Ovale Closure Risk of Atrial Arrhythmia or Tachycardia | Arrhythmias, Cardiac, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cryptogenic Ischemic Stroke, Pathologic Processes, Pathological Conditions, Signs and Symptoms, atrial fibrillation, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, ischemic stroke, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Active, not recruiting | Phase 3 | 2026-09-09 | NCT05213104 | |
| Abbott Structural Heart Device Registry | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, cardiovascular disorder, congenital heart disease, heart disorder, heart septal defect, heart valve disorder, patent foramen ovale | Recruiting | Not stated | 2026-09-01 | NCT06590467 | |
| Hummingbird ICE Study | Arrhythmias, Cardiac, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Pathologic Processes, Pathological Conditions, Signs and Symptoms, atrial fibrillation, atrial septal defect, cardiovascular disorder, congenital heart disease, heart disorder, heart septal defect, heart valve disorder, patent foramen ovale, tricuspid valve disorder | Not yet recruiting | Not stated | 2026-08-19 | NCT07552272 | |
| The Cardiovascular Effects of Patent Foramen Ovale in Hypoxia | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hypoxia, Pathological Conditions, Signs and Symptoms, Respiration Disorders, Signs and Symptoms, Signs and Symptoms, Respiratory, altitude sickness, atrial septal defect, cardiovascular disorder, congenital heart disease, heart disorder, heart septal defect, high altitude pulmonary edema, patent foramen ovale, respiratory system disorder | Not yet recruiting | Not stated | 2026-08-03 | NCT07742540 | |
| GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Recruiting | Not applicable | 2026-07-30 | NCT03821129 | |
| Safety and Efficacy of the Patent Foramen Ovale Suture System for the Closure of Patent Foramen Ovale | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, cardiovascular disorder, congenital heart disease, heart disorder, heart septal defect, patent foramen ovale | Not yet recruiting | Not applicable | 2026-07-27 | NCT07726927 | |
| Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cryptogenic Ischemic Stroke, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, ischemic stroke, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Recruiting | Not applicable | 2026-07-27 | NCT07172464 | |
| Long-term Outcomes After Percutaneous Patent Foramen Ovale Closure (Severance PFO Registry) | Arrhythmias, Cardiac, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cryptogenic Ischemic Stroke, Pathologic Processes, Pathological Conditions, Signs and Symptoms, atrial fibrillation, atrial septal defect, brain disorder, brain ischemia, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, ischemic stroke, nervous system disorder, patent foramen ovale, stroke disorder, transient ischemic attack, vascular disorder | Recruiting | Not stated | 2026-07-23 | NCT07724171 | |
| Evaluating Percutaneous Repair Of The Atrial Septum With A Novel PFO Occluder: The PROTEA-PFO OUS Study | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cryptogenic Ischemic Stroke, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, ischemic stroke, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Recruiting | Not applicable | 2026-07-13 | NCT07698951 | |
| CeraFlex PFO Closure System PMCF Study | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, cardiovascular disorder, congenital heart disease, heart disorder, heart septal defect, patent foramen ovale | Recruiting | Not stated | 2026-06-10 | NCT06120270 | |
| Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Active, not recruiting | Not applicable | 2026-05-22 | NCT05069558 | |
| Standardized Goal-Directed vs. Self-Directed Valsalva Maneuver for the Assessment of Patent Foramen Ovale | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Recruiting | Not applicable | 2026-04-30 | NCT06670781 | |
| Pulmonary Embolism and Right-to-Left Shunts | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Embolism, Embolism and Thrombosis, Pulmonary Arteriovenous Fistulas, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, lung disorder, nervous system disorder, patent foramen ovale, pulmonary embolism, respiratory system disorder, stroke disorder, vascular disorder | Recruiting | Not stated | 2026-04-09 | NCT07519876 | |
| Medical Treatment With or Without Transcatheter Patent Foramen Ovale Closure | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cryptogenic Ischemic Stroke, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, ischemic stroke, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Recruiting | Not applicable | 2026-03-27 | NCT05907694 | |
| PFO Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Aged 60 to 80 Years | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cryptogenic Ischemic Stroke, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, ischemic stroke, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Recruiting | Phase 3 | 2026-03-24 | NCT05387954 | |
| Discontinuation of Antithrombotic Treatment Following Patent Foramen Ovale Closure in Young Patients With Cryptogenic Stroke | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemorrhage, Pathologic Processes, Pathological Conditions, Signs and Symptoms, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, ischemic stroke, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Recruiting | Not applicable | 2026-03-24 | NCT04475510 | |
| SENIOR: Stroke Prevention in the Elderly by Patent Foramen Ovale closuRe vs Anticoagulation | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, ischemic stroke, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Recruiting | Not stated | 2026-03-23 | NCT07479147 | |
| NobleStitch EL STITCH Trial is a PFO Comparative Trial | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, ischemic stroke, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Recruiting | Not applicable | 2026-03-23 | NCT04339699 | |
| AMPLATZER PFO Occluder Post Approval Study | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Active, not recruiting | Not applicable | 2026-03-11 | NCT03309332 | |
| Non-Invasive Detection of Right-to-Left Cardiac Shunts | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, ischemic stroke, nervous system disorder, patent foramen ovale, stroke disorder, vascular disorder | Recruiting | Not stated | 2026-02-19 | NCT07420400 |