ACTH-dependent Cushing syndrome
ACTH-dependent Cushing syndrome
Explore linked clinical trials. Standard reference: MONDO:002052820 results · Page 1 of 1
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome | ACTH-dependent Cushing syndrome, Cushing syndrome, Neoplasms by Histologic Type, Neoplasms by Site, Nutritional and Metabolic Diseases, Paraneoplastic Endocrine Syndromes, adenocarcinoma, adrenal cortex disorder, adrenal cortex neoplasm, adrenal gland cancer, adrenal gland disorder, adrenal gland hyperfunction, brain disorder, carcinoma, cardiovascular disorder, central nervous system disorder, diabetes mellitus, ectopic ACTH secretion syndrome, endocrine system disorder, epithelial neoplasm, glucose metabolism disease, hyperpituitarism, hypertensive disorder, hypothalamic disorder, malignant endocrine neoplasm, metabolic disease, neoplasm, nervous system disorder, paraneoplastic syndrome, pituitary gland disorder, type 2 diabetes mellitus, vascular disorder | Active, not recruiting | Phase 2 | 2026-10-09 | NCT03604198 | |
| PRESTO: A Phase III Randomised Controlled Trial of Dose-escalated Proton Beam Therapy Versus Standard of Care Radiotherapy for Functioning Pituitary Tumours | ACTH-dependent Cushing syndrome, Bone Diseases, Endocrine, Growth Hormone-Secreting Pituitary Adenoma, Neoplasms by Histologic Type, Neoplasms by Site, Pituitary Neoplasms, acromegaly, adenoma, bone disorder, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, epithelial neoplasm, hyperpituitarism, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, musculoskeletal system disorder, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancer | Not yet recruiting | Phase 3 | 2026-10-01 | NCT07813351 | |
| An Investigation of Pituitary Tumors and Related Hypothalmic Disorders | ACTH-dependent Cushing syndrome, Bone Diseases, Developmental, Bone Diseases, Endocrine, Carcinogenesis, Combined Pituitary Hormone Deficiency, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Neoplasms by Histologic Type, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Pituitary Neoplasms, acromegaly, adenoma, bone disorder, brain disorder, central nervous system disorder, endocrine system disorder, epithelial neoplasm, hyperpituitarism, hypothalamic disorder, malignant endocrine neoplasm, musculoskeletal system disorder, neoplasm, nervous system disorder, pituitary gigantism, pituitary gland disorder, prolactin-producing pituitary gland adenoma | Recruiting | Not stated | 2026-09-22 | NCT00001595 | |
| Recovery From Cushing Syndrome and Mild Autonomous Cortisol Secretion (MACS) | ACTH-dependent Cushing syndrome, Cushing syndrome, adrenal gland disorder, adrenal gland hyperfunction, brain disorder, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, nervous system disorder, pituitary gland disorder | Recruiting | Not stated | 2026-09-18 | NCT04543253 | |
| Long-Term Follow-Up of Survivors of Pediatric Cushing Disease | ACTH-dependent Cushing syndrome, Insulin Resistance, Nutritional and Metabolic Diseases, brain disorder, central nervous system disorder, endocrine system disorder, glucose metabolism disease, hyperinsulinism, hyperpituitarism, hypothalamic disorder, metabolic disease, nervous system disorder, pituitary gland disorder | Recruiting | Not stated | 2026-09-16 | NCT03831958 | |
| A Trial of Lu AG13909 in Adult Participants With Cushing's Disease | ACTH-dependent Cushing syndrome, brain disorder, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, nervous system disorder, pituitary gland disorder | Recruiting | Phase 2 | 2026-08-21 | NCT06471829 | |
| A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome | ACTH-dependent Cushing syndrome, Cushing syndrome, Paraneoplastic Endocrine Syndromes, adrenal gland disorder, adrenal gland hyperfunction, brain disorder, central nervous system disorder, ectopic ACTH secretion syndrome, endocrine system disorder, hyperpituitarism, hypothalamic disorder, neoplasm, nervous system disorder, paraneoplastic syndrome, pituitary gland disorder | Active, not recruiting | Phase 1 / Phase 2 | 2026-08-19 | NCT05804669 | |
| Fimepinostat, Combination HDAC and Pi3-kinase Inhibitor Tumor-Directed Therapy for Cushing Disease | ACTH-dependent Cushing syndrome, brain disorder, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, nervous system disorder, pituitary gland disorder | Recruiting | Phase 2 | 2026-07-17 | NCT05971758 | |
| Use of [18F]FET PET-MRI to Improve Detection of Pituitary Adenomas in Cushing's Disease | ACTH-dependent Cushing syndrome, brain disorder, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, nervous system disorder, pituitary gland disorder | Enrolling by invitation | Not applicable | 2026-07-06 | NCT07108244 | |
| FET PET/CT Imaging To Localize Pituitary Adenomas In Cushing Disease | ACTH-dependent Cushing syndrome, Neoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancer | Recruiting | Early phase 1 | 2026-06-22 | NCT07460232 | |
| Combination Osilodrostat and Cabergoline in Cushing's Disease | 46,XX disorder of sex development, ACTH-dependent Cushing syndrome, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Hyperandrogenism, Male Urogenital Diseases, Nutritional and Metabolic Diseases, Urogenital Abnormalities, Urogenital Diseases, Water-Electrolyte Imbalance, adrenal gland disorder, adrenocortical insufficiency, adrenogenital syndrome, brain disorder, cardiovascular disorder, central nervous system disorder, disorder of sexual differentiation, endocrine system disorder, gonadal disorder, hyperpituitarism, hypertensive disorder, hypothalamic disorder, metabolic disease, nervous system disorder, pituitary gland disorder, potassium deficiency disease, vascular disorder | Enrolling by invitation | Phase 4 | 2026-05-22 | NCT07603466 | |
| DDAVP for Pituitary Adenoma | ACTH-dependent Cushing syndrome, Neoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancer | Recruiting | Not applicable | 2026-04-09 | NCT04569591 | |
| Evaluation of Positron Emission Tomography (PET) With [18F]FET for the Detection of ACTH-Secreting Corticotroph Pituitary Neuroendocrine Tumors. | ACTH-dependent Cushing syndrome, ACTH-producing pituitary gland neoplasm, Cushing disease due to pituitary adenoma, Neoplasms by Histologic Type, Neoplasms by Site, Pituitary Neoplasms, adenoma, brain disorder, central nervous system disorder, endocrine system disorder, epithelial neoplasm, hyperpituitarism, hypothalamic disorder, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland disorder | Recruiting | Not stated | 2026-03-11 | NCT07463625 | |
| Evaluation of Intraoperative Contrast Enhanced Ultrasound for the Identification of Pituitary Adenoma in Cushing's Disease Compared to Other Pituitary Tumors | ACTH-dependent Cushing syndrome, Neoplasms by Site, Pituitary Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancer | Recruiting | Not stated | 2026-01-13 | NCT07335315 | |
| Discriminant Capacity and Thresholds of Salivary Cortisol in Chemiluminescence in the Diagnosis of Hypercorticisms | ACTH-dependent Cushing syndrome, brain disorder, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, nervous system disorder, pituitary gland disorder | Active, not recruiting | Not stated | 2025-11-17 | NCT03974789 | |
| Collecting Information About Treatment Results for Patients With Cushing's Syndrome | ACTH-dependent Cushing syndrome, Cushing syndrome, adrenal gland disorder, adrenal gland hyperfunction, brain disorder, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, nervous system disorder, pituitary gland disorder | Recruiting | Not stated | 2025-10-23 | NCT03364803 | |
| Multicenter Study of Seliciclib (R-roscovitine) for Cushing Disease | ACTH-dependent Cushing syndrome, brain disorder, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, nervous system disorder, pituitary gland disorder | Recruiting | Phase 2 | 2025-09-11 | NCT03774446 | |
| Postoperative Thrombosis Prevention in Patients With CD | ACTH-dependent Cushing syndrome, Embolism, Embolism and Thrombosis, brain disorder, cardiovascular disorder, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, lung disorder, nervous system disorder, pituitary gland disorder, pulmonary embolism, respiratory system disorder, vascular disorder | Active, not recruiting | Not applicable | 2025-07-02 | NCT04486859 | |
| Modified Desmopressin (mDesmo) Using Cold-Kit for PET/CT | ACTH-dependent Cushing syndrome, Cushing syndrome, adrenal gland disorder, adrenal gland hyperfunction, brain disorder, central nervous system disorder, endocrine system disorder, hyperpituitarism, hypothalamic disorder, nervous system disorder, pituitary gland disorder | Recruiting | Not stated | 2025-05-20 | NCT06962202 | |
| Osilodrostat Therapy and 11C-methionine PET to Improve Corticotroph Adenoma Detection | ACTH-dependent Cushing syndrome, ACTH-producing pituitary gland adenoma, Cushing disease due to pituitary adenoma, Cushing syndrome, Neoplasms by Histologic Type, Neoplasms by Site, Pituitary Neoplasms, adenoma, adrenal gland disorder, adrenal gland hyperfunction, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, epithelial neoplasm, hyperpituitarism, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, neoplasm, nervous system disorder, pituitary gland adenoma, pituitary gland disorder, supratentorial cancer | Not yet recruiting | Not stated | 2024-12-03 | NCT06701838 |