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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancerrenal pelvis/ureter urothelial carcinomaRecruitingPhase 2 / Phase 32026-10-08NCT04628767
uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With JelmytoDisease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, Urogenital Diseases, Urogenital Neoplasms, benign urinary system neoplasm, carcinoma, epithelial neoplasm, neoplasm, renal pelvis urothelial carcinoma, renal pelvis/ureter urothelial carcinoma, transitional cell carcinoma, urinary system disorder, urothelial carcinomaRecruitingNot stated2026-09-29NCT05874921
Disitamab Vedotin Plus Radiotherapy for Adjuvant Treatment of HER2-Expressing Cisplatin-Ineligible Upper Tract Urothelial Carcinomarenal pelvis/ureter urothelial carcinomaRecruitingPhase 32026-09-28NCT07498907
Photodynamic Diagnosis of Upper Tract Urothelial Carcinoma Using Fluorescence Endoscopy and Oral 5-ALAFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, benign urinary system neoplasm, kidney cancer, kidney disorder, neoplasm, renal pelvis/ureter urothelial carcinoma, urinary system disorderRecruitingPhase 22026-09-18NCT06948552
Screening for Urological Malignancies Using a Urine Exfoliated Cell Fluorescence Assay in a Hematuria Populationrenal pelvis/ureter urothelial carcinomaRecruitingNot stated2026-09-10NCT07813260
A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving TrialFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, benign urinary system neoplasm, carcinoma, epithelial neoplasm, neoplasm, renal pelvis/ureter urothelial carcinoma, transitional cell carcinoma, urinary bladder cancer, urinary bladder disorder, urinary bladder neoplasm, urinary system disorder, urothelial carcinomaRecruitingNot applicable2026-09-10NCT06040762
Circulating Tumor DNA (ctDNA) in High Grade Upper Tract Urothelial Cancer (UTUC)renal pelvis/ureter urothelial carcinomaNot yet recruitingNot stated2026-09-01NCT07793240
Validation of a Circulating Tumor DNA Blood Test in Muscle-Invasive Bladder and Upper Tract Urothelial CancerNeoplasm, Residual, Neoplasms by Histologic Type, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, carcinoma, epithelial neoplasm, neoplasm, renal pelvis/ureter urothelial carcinoma, transitional cell carcinomaRecruitingNot stated2026-08-10NCT07756437
OptiCross HD IVUS for Assessing Invasion Depth in Upper Tract Urothelial Carcinomarenal pelvis/ureter urothelial carcinomaNot yet recruitingNot applicable2026-08-07NCT07751796
Neoadjuvant Gemcitabine Plus Trastuzumab Rezetecan in HER2-positive UTUCrenal pelvis/ureter urothelial carcinomaRecruitingPhase 22026-08-03NCT07741448
Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinomarenal pelvis/ureter urothelial carcinomaRecruitingPhase 2 / Phase 32026-08-03NCT06124976
ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Studyrenal pelvis/ureter urothelial carcinomaActive, not recruitingPhase 32026-07-30NCT04620239
Neoadjuvant Disitamab Vedotin, Toripalimab, and Radiotherapy for High-risk UTUC ( LUXUS07.1 )renal pelvis/ureter urothelial carcinomaNot yet recruitingPhase 22026-07-22NCT07720921
Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancerrenal pelvis/ureter urothelial carcinomaRecruitingPhase 22026-07-16NCT05775471
Office-Based Ureteroscopy Utilizing a Single Use Digital, Flexible Ureteroscope for Upper Tract Urothelial Carcinomarenal pelvis/ureter urothelial carcinomaRecruitingNot applicable2026-07-10NCT07630155
Non-invasive Urinary Genomics-Based Risk Assessment for Early Urothelial Carcinoma DiagnosisFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, Urogenital Neoplasms, benign urinary system neoplasm, carcinoma, disease, epithelial neoplasm, neoplasm, renal pelvis/ureter urothelial carcinoma, transitional cell carcinoma, urinary bladder disorder, urinary bladder neoplasm, urinary system disorderRecruitingNot stated2026-07-02NCT07614594
Radical Nephroureterectomy With vs Without Template Lymph Node Dissection in High-Risk Upper Tract Urothelial Carcinoma (T-LND UTUC)renal pelvis/ureter urothelial carcinomaRecruitingNot applicable2026-06-25NCT07321210
Biomarker-Enriched Kidney-Preserving Strategy With Disitamab Vedotin Plus Tislelizumab in HER2-Positive High-Risk Upper Tract Urothelial Carcinomarenal pelvis/ureter urothelial carcinomaNot yet recruitingPhase 22026-05-13NCT07584733
Flexible Ureterorenoscopy for Surveillance of Upper Tract Urothelial Carcinomarenal pelvis/ureter urothelial carcinomaNot yet recruitingNot applicable2026-05-05NCT07557563
Multimodal Kidney-Sparing Strategy for High-Risk Upper Tract Urothelial Carcinomarenal pelvis/ureter urothelial carcinomaNot yet recruitingNot stated2026-04-24NCT07504939
Dual-Target Nectin-4/HER2 CAR-NK Cells in Advanced Urothelial CarcinomaFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, benign urinary system neoplasm, carcinoma, epithelial neoplasm, neoplasm, renal pelvis/ureter urothelial carcinoma, transitional cell carcinoma, urinary bladder cancer, urinary bladder disorder, urinary bladder neoplasm, urinary system disorder, urothelial carcinomaRecruitingPhase 12026-03-25NCT07492628
NECTAR Study: Neoadjuvant Toripalimab + 9MW2821 for Local UTUCDisease Attributes, Disease Progression, Pathologic Complete Response, Pathologic Processes, Pathological Conditions, Signs and Symptoms, renal pelvis/ureter urothelial carcinomaNot yet recruitingPhase 22026-02-17NCT07412171
Bladder EpiCheck European Haematuria StudyFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Hematuria, Hemorrhage, Male Urogenital Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urination Disorders, Urogenital Diseases, bladder transitional cell carcinoma, renal pelvis/ureter urothelial carcinoma, urinary system disorderRecruitingNot stated2026-01-22NCT06818136
Cisplatin-Based Chemotherapy Followed by Maintenance Avelumab in UTUCrenal pelvis/ureter urothelial carcinomaRecruitingPhase 22025-11-06NCT07225374
Ambulatory Flexible URS for UTUC Surveillancerenal pelvis/ureter urothelial carcinomaRecruitingPhase 12025-09-15NCT06848868