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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated CancersAnal Cancer, Digestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Head and Neck Neoplasms, Male Urogenital Diseases, Neoplasms by Site, Otorhinolaryngologic Neoplasms, Pharyngeal Diseases, Stomatognathic Diseases, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, anus disorder, anus neoplasm, cervix disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, female reproductive system disorder, female reproductive system neoplasm, human papillomavirus-related penile squamous cell carcinoma, human papillomavirus-related squamous cell carcinoma, intestinal disorder, male reproductive organ cancer, male reproductive system disorder, neoplasm, otorhinolaryngologic disease, penile cancer, penile disorder, penile neoplasm, rectal disorder, rectal neoplasm, uterine disorder, vaginal cancer, vaginal disorder, vulva cancer, vulvar diseaseRecruitingPhase 1 / Phase 22026-10-06NCT05639972
A Study Comparing Personalized Radiation Therapy With Standard Radiation Therapy in People With HPV-Positive Throat Cancerhuman papillomavirus-related squamous cell carcinomaRecruitingPhase 32026-09-24NCT06563479
CASCADE 2002: PROTECT Study, "PRObiotics to TrEat Anal preCancer TrialHigh-Grade Squamous Intraepithelial Lesions, Morphological and Microscopic Findings, Pathological Conditions, Signs and Symptoms, Squamous Intraepithelial Lesions, human papillomavirus-related squamous cell carcinomaRecruitingPhase 22026-09-15NCT06949800
Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT StudyHead and Neck Neoplasms, Neoplasms by Site, Otorhinolaryngologic Neoplasms, Pharyngeal Diseases, Stomatognathic Diseases, human papillomavirus-related squamous cell carcinoma, neoplasm, otorhinolaryngologic diseaseRecruitingPhase 22026-08-05NCT04900623
E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated CancersAnal Cancer, Digestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Head and Neck Neoplasms, Male Urogenital Diseases, Neoplasm Metastasis, Neoplasms by Site, Neoplastic Processes, Otorhinolaryngologic Neoplasms, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Pharyngeal Diseases, Stomatognathic Diseases, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, anus disorder, anus neoplasm, cervix disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, female reproductive system disorder, female reproductive system neoplasm, human papillomavirus-related penile squamous cell carcinoma, human papillomavirus-related squamous cell carcinoma, intestinal disorder, male reproductive organ cancer, male reproductive system disorder, metastatic malignant neoplasm, neoplasm, otorhinolaryngologic disease, penile cancer, penile disorder, penile neoplasm, rectal disorder, rectal neoplasm, uterine disorder, vaginal cancer, vaginal disorder, vulva cancer, vulvar diseaseRecruitingPhase 22026-06-12NCT05686226
Trial of Cemiplimab, or Cemip-Chemo Followed by Biomarker-guided Treatment for Pts w/HPV H&N Cahuman papillomavirus-related squamous cell carcinomaRecruitingPhase 22026-03-03NCT04988074
A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid TumorsAdnexal Diseases, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Head and Neck Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, cervix disorder, endocrine system disorder, female reproductive system disorder, female reproductive system neoplasm, gonadal disorder, head and neck cancer, human papillomavirus-related penile squamous cell carcinoma, human papillomavirus-related squamous cell carcinoma, malignant endocrine neoplasm, melanocytic neoplasm, melanoma, neoplasm, neuroendocrine neoplasm, ovarian cancer, ovarian disorder, primitive neuroectodermal tumor, skin disorder, skin neoplasm, uterine disorderActive, not recruitingPhase 12025-11-17NCT05973487
Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive CarcinomaDigestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Head and Neck Neoplasms, Male Urogenital Diseases, Neoplasms by Site, Otorhinolaryngologic Neoplasms, Pharyngeal Diseases, Stomatognathic Diseases, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, anus disorder, anus neoplasm, cervix disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, female reproductive system disorder, female reproductive system neoplasm, human papillomavirus-related penile squamous cell carcinoma, human papillomavirus-related squamous cell carcinoma, intestinal disorder, male reproductive organ cancer, male reproductive system disorder, neoplasm, otorhinolaryngologic disease, penile disorder, penile neoplasm, rectal disorder, rectal neoplasm, uterine disorder, vaginal cancer, vaginal disorder, vulva cancer, vulvar diseaseNot yet recruitingPhase 1 / Phase 22024-07-17NCT06505551
Autologous T Cells Targeting HPV16 HPV18 & Survivin in Patients With R/R HPV-related Oropharyngeal CancersDisease Attributes, Head and Neck Neoplasms, Neoplasm Metastasis, Neoplasms by Histologic Type, Neoplasms by Site, Neoplastic Processes, Otorhinolaryngologic Neoplasms, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Pharyngeal Diseases, Recurrence, Stomatognathic Diseases, carcinoma, epithelial neoplasm, head and neck cancer, head and neck squamous cell carcinoma, human papillomavirus-related squamous cell carcinoma, neoplasm, oropharynx squamous cell carcinoma, otorhinolaryngologic disease, squamous cell carcinomaNot yet recruitingPhase 12024-01-16NCT05582590